Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Diego Vieyra"'
Autor:
Suzette Girgis, Shun Xin Wang Lin, Kodandaram Pillarisetti, Raluca Verona, Diego Vieyra, Tineke Casneuf, Damien Fink, Xin Miao, Yang Chen, Tara Stephenson, Arnob Banerjee, Brandi W. Hilder, Jeffery Russell, Jeffrey Infante, Yusri Elsayed, Jennifer Smit, Jenna D. Goldberg
Publikováno v:
Blood Advances. 7:644-648
B-cell maturation antigen (BCMA) is selectively expressed as a surface protein on plasma cells and is a validated target for multiple myeloma (MM). A soluble form of BCMA (sBCMA) is elevated in the sera of patients with MM. The bispecific antibodies
Autor:
Yaël C. Cohen, Philippe Moreau, Jaszianne Tolbert, Xiang Qin, Xuewen Ma, Diego Vieyra, Angelique Langlois, Christelle Courtoux, William Terry, Lixia Pei, Christoph Heuck, Peter Voorhees
Publikováno v:
Blood. 140:4418-4419
Autor:
Xin Miao, Jenna D. Goldberg, Jennifer Smit, Jeffery S. Russell, Raluca Verona, Tara Stephenson, Suzette Girgis, Tineke Casneuf, Kodandaram Pillarisetti, Arnob Banerjee, Brandi Hilder, Yang Chen, Damien Fink, Diego Vieyra, Shun Xin Wang Lin
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 21:S39-S40
Background B-cell maturation antigen (BCMA, CD269), a single transmembrane protein, can be shed as a soluble 6 kilodalton protein fragment (sBCMA) upon cleavage at the transmembrane domain by γ-secretase. Given its selective expression in the B-cell
Autor:
Raluca Verona, Tuna Mutis, Diego Vieyra, Tineke Casneuf, Carolien Duetz, Monique C. Minnema, Christie P. M. Verkleij, Saskia K. Klein, Niels W.C.J. van de Donk, Paola M. Homan-Weert, Kristine A. Frerichs, Greet Vanhoof, Pieter Sonneveld, Mark-David Levin, Medya M. Shikhagaie, Tina Smets, Yann Abraham, Diana Cortes-Selva, Gerard M. J. Bos, Annemiek Broyl, Marie José Kersten, Sonja Zweegman, Maria Krevvata, Laure van Steenbergen
Publikováno v:
Blood. 138:728-728
Introduction: Daratumumab (DARA)-based regimens are effective and well tolerated in both newly diagnosed and relapsed/refractory multiple myeloma (RRMM) patients. However, the prognosis for patients who have become refractory to proteasome inhibitors
Autor:
Jennifer Smit, Jenna D. Goldberg, Diego Vieyra, Suzette Girgis, Tineke Casneuf, Brandi Hilder, Yang Chen, Kodandaram Pillarisetti, Jeffery S. Russell, Raluca Verona, Arnob Banerjee, Xin Miao, Tara Stephenson, Shun Xin Wang Lin, Damien Fink
Publikováno v:
Journal of Clinical Oncology. 39:8047-8047
8047 Background: B-cell maturation antigen (BCMA, CD269) is a single transmembrane protein that is selectively expressed in the B-cell lineage and is a validated target for multiple myeloma. BCMA exists as both surface protein and as a free soluble f
Autor:
François-Michel Boisvert, Karl Riabowol, Diego Vieyra, David P. Bazett-Jones, Dallan Young, Paul Bonnefin, Michelle S. Scott
Publikováno v:
Journal of Cell Science. 114:3455-3462
Previous studies have shown that UV-induced binding of p21(WAF1) to PCNA through the PCNA-interacting protein (PIP) domain in p21(WAF1) promotes a switch from DNA replication to DNA repair by altering the PCNA protein complex. Here we show that the p
Autor:
François-Michel Boisvert, Michelle S. Scott, Randal N. Johnston, Diego Vieyra, David P. Bazett-Jones, Karl Riabowol
Publikováno v:
Nucleic Acids Research. 29:2052-2058
The ING1 candidate tumor suppressor is downregulated in a variety of primary tumors and established cancer cell lines. Blocking its expression experimentally promotes unregulated growth in vitro and in vivo, using cell and animal models. Alternative
Publikováno v:
Hybridoma. 19:161-165
Nine monoclonal antibodies (MAbs) against human and rodent ING1 protein have been generated using an IL6-secreting mouse myeloma line. These antibodies are all effective in recognizing ING1 protein in ELISAs, Western blot assays, and by indirect immu
Autor:
Diego, Vieyra, Donna L, Senger, Tatsuya, Toyama, Huong, Muzik, Penny M A, Brasher, Randal N, Johnston, Karl, Riabowol, Peter A, Forsyth, Tatsuya, Toyam
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 9(16 Pt 1)
Clinical and experimental evidence suggest that the p33ING1b candidate tumor suppressor functionally cooperates with p53 in controlling biochemical and biological functions. Because p53 is frequently mutated in brain tumors and the ING1 locus maps to
Autor:
Hiromi, Kataoka, Paul, Bonnefin, Diego, Vieyra, Xiaolan, Feng, Yasuo, Hara, Yutaka, Miura, Takashi, Joh, Hidekazu, Nakabayashi, Homayoun, Vaziri, Curtis C, Harris, Karl, Riabowol
Publikováno v:
Cancer research. 63(18)
The ING family of proteins is involved in the regulation of diverse processes ranging from cell cycle and cellular senescence to apoptosis. These effects are most likely through activation of acetylation-dependent pathways that ultimately alter gene