Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Diego Scheggia"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Social decision-making requires the ability to balance both the interests of the self and the interests of others to survive in social environments. Empathy is essential to the regulation of this type of interaction, and it often sustains relevant pr
Externí odkaz:
https://doaj.org/article/b983f51024dc44279fa7728e37911086
Autor:
Elena Ferrari, Diego Scheggia, Elisa Zianni, Maria Italia, Marta Brumana, Luca Palazzolo, Chiara Parravicini, Andrea Pilotto, Alessandro Padovani, Elena Marcello, Ivano Eberini, Paolo Calabresi, Monica Diluca, Fabrizio Gardoni
Publikováno v:
Pharmacological Research, Vol 183, Iss , Pp 106375- (2022)
Toxic aggregates of α-synuclein (αsyn) are considered key drivers of Parkinson’s disease (PD) pathology. In early PD, αsyn induces synaptic dysfunction also modulating the glutamatergic neurotransmission. However, a more detailed understanding o
Externí odkaz:
https://doaj.org/article/20c91ac6ed9b46d2bf4b92c40afa63f2
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 15 (2021)
Adolescence is a developmental period crucial for the maturation of higher-order cognitive functions. Indeed, adolescence deficits in executive functions are strong predictors of increased vulnerability to several mental disabilities later in life. H
Externí odkaz:
https://doaj.org/article/d666d57ca38846b5a53ff8a5a8305160
Autor:
Nataliya Gorinski, Monika Bijata, Sonal Prasad, Alexander Wirth, Dalia Abdel Galil, Andre Zeug, Daria Bazovkina, Elena Kondaurova, Elizabeth Kulikova, Tatiana Ilchibaeva, Monika Zareba-Koziol, Francesco Papaleo, Diego Scheggia, Gaga Kochlamazashvili, Alexander Dityatev, Ian Smyth, Adam Krzystyniak, Jakub Wlodarczyk, Diethelm W. Richter, Tatyana Strekalova, Stephan Sigrist, Claudia Bang, Lisa Hobuß, Jan Fiedler, Thomas Thum, Vladimir S. Naumenko, Ghanshyam Pandey, Evgeni Ponimaskin
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Palmitoylation is a post translational modification that regulates GPCR activity. Here the authors show that palmitoylation of 5-HT1AR by the palmitoyltransferase enzyme ZDHHC21 contributes to depression-like behaviour in rodents and might be implica
Externí odkaz:
https://doaj.org/article/b7ca995a09f14264a865413198bdb889
Autor:
Diego Scheggia, Rosa Mastrogiacomo, Maddalena Mereu, Sara Sannino, Richard E. Straub, Marco Armando, Francesca Managò, Simone Guadagna, Fabrizio Piras, Fengyu Zhang, Joel E. Kleinman, Thomas M. Hyde, Sanne S. Kaalund, Maria Pontillo, Genny Orso, Carlo Caltagirone, Emiliana Borrelli, Maria A. De Luca, Stefano Vicari, Daniel R. Weinberger, Gianfranco Spalletta, Francesco Papaleo
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Patients with schizophrenia show varied response to antipsychotics. Here, the authors demonstrate in patients under antipsychotics treatment that a haplotype associated with lower dysbindin-1 expression correlated with better executive functions, pro
Externí odkaz:
https://doaj.org/article/0e5f124f37b14a83811e7cceee5dc56c
Autor:
Fabrizio Gardoni, Jennifer Stanic, Diego Scheggia, Alberto Benussi, Barbara Borroni, Monica Di Luca
Publikováno v:
Cells, Vol 10, Iss 1, p 77 (2021)
The role of autoimmunity in central nervous system (CNS) disorders is rapidly expanding. In the last twenty years, different types of autoantibodies targeting subunits of ionotropic glutamate receptors have been found in a variety of patients affecte
Externí odkaz:
https://doaj.org/article/dc7921e32dea439d8094a89d70179dd8
Autor:
Francesca Managò, Maddalena Mereu, Surjeet Mastwal, Rosa Mastrogiacomo, Diego Scheggia, Marco Emanuele, Maria A. De Luca, Daniel R. Weinberger, Kuan Hong Wang, Francesco Papaleo
Publikováno v:
Cell Reports, Vol 16, Iss 8, Pp 2116-2128 (2016)
Human genetic studies have recently suggested that the postsynaptic activity-regulated cytoskeleton-associated protein (Arc) complex is a convergence signal for several genes implicated in schizophrenia. However, the functional significance of Arc in
Externí odkaz:
https://doaj.org/article/23adcd9f1e4948b1a9390976cc0bce29
Autor:
Diego Scheggia, Rosa Mastrogiacomo, Maddalena Mereu, Sara Sannino, Richard E. Straub, Marco Armando, Francesca Managò, Simone Guadagna, Fabrizio Piras, Fengyu Zhang, Joel E. Kleinman, Thomas M. Hyde, Sanne S. Kaalund, Maria Pontillo, Genny Orso, Carlo Caltagirone, Emiliana Borrelli, Maria A. De Luca, Stefano Vicari, Daniel R. Weinberger, Gianfranco Spalletta, Francesco Papaleo
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
In the original version of this Article, references in the Methods section incorrectly referred to references in the Supplementary References section. The relevant references (now numbered 20, 27, 42, 47, 69–80) have been removed from the Supplemen
Externí odkaz:
https://doaj.org/article/b9def1781218440784dceee7ac28fc40
Autor:
Luca Giancardo, Diego Sona, Huiping Huang, Sara Sannino, Francesca Managò, Diego Scheggia, Francesco Papaleo, Vittorio Murino
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74557 (2013)
Social interactions are made of complex behavioural actions that might be found in all mammalians, including humans and rodents. Recently, mouse models are increasingly being used in preclinical research to understand the biological basis of social-r
Externí odkaz:
https://doaj.org/article/070a96cc41084215a6c2b78edd8da095
Autor:
Diego Scheggia, Filippo La Greca, Federica Maltese, Giulia Chiacchierini, Maria Italia, Cinzia Molent, Fabrizio Bernardi, Giulia Coccia, Nicolò Carrano, Elisa Zianni, Fabrizio Gardoni, Monica Di Luca, Francesco Papaleo
Publikováno v:
Nature Neuroscience. 25:1505-1518
Decisions that favor one's own interest versus the interest of another individual depend on context and the relationships between individuals. The neurobiology underlying selfish choices or choices that benefit others is not understood. We developed