Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Diego Rodríguez-Penas"'
Autor:
José Seijas-Amigo, Diego Rodríguez-Penas, Ana Estany-Gestal, Pedro Suárez-Artime, María Santamaría-Cadavid, José Ramón González-Juanatey
Publikováno v:
Farmacia Hospitalaria, Vol 45, Iss 03, Pp 150-154 (2021)
Objective: PCSK9 inhibitors have been shown to reduce LDLc by up to about 60% and 85% when used with high doses of statins and ezetimibe (2019 ESC/EAS Guidelines). These therapies may lead to very low levels of LDLc and have been associated with poss
Externí odkaz:
https://doaj.org/article/0fa7210cbe5e4aa9986ca92c28f9233c
Autor:
Diego Rodríguez-Penas, Sandra Feijóo-Bandín, Vanessa García-Rúa, Ana Mosquera-Leal, Darío Durán, Alfonso Varela, Manuel Portolés, Esther Roselló-Lletí, Miguel Rivera, Carlos Diéguez, Oreste Gualillo, José Ramón González-Juanatey, Francisca Lago
Publikováno v:
Cellular Physiology and Biochemistry, Vol 37, Iss 1, Pp 176-192 (2015)
Background: The adipokine chemerin has been associated with cardiovascular disease. We investigated the effects of chemerin on viability and intracellular signalling in murine cardiomyocytes, and the effects of insulin and TNF-α on cardiomyocyte che
Externí odkaz:
https://doaj.org/article/4c84243e242d4378be8f0d275c4b1ff1
Autor:
Sandra Feijóo-Bandín, Alana Aragón-Herrera, Diego Rodríguez-Penas, Manuel Portolés, Esther Roselló-Lletí, Miguel Rivera, José R. González-Juanatey, Francisca Lago
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Despite the great effort of the medical community during the last decades, cardiovascular diseases remain the leading cause of death worldwide, increasing their prevalence every year mainly due to our new way of life. In the last years, the study of
Externí odkaz:
https://doaj.org/article/be55c664fde646f68a3b3792f2f72656
Autor:
Vanessa García-Rúa, Manuel Francisco Otero, Pamela Virginia Lear, Diego Rodríguez-Penas, Sandra Feijóo-Bandín, Teresa Noguera-Moreno, Manuel Calaza, María Álvarez-Barredo, Ana Mosquera-Leal, John Parrington, Josep Brugada, Manuel Portolés, Miguel Rivera, José Ramón González-Juanatey, Francisca Lago
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e37505 (2012)
Heart failure (HF) involves alterations in metabolism, but little is known about cardiomyopathy-(CM)-specific or diabetes-independent alterations in gene expression of proteins involved in fatty-acid (FA) uptake and oxidation or in calcium-(Ca(2+))-h
Externí odkaz:
https://doaj.org/article/e3786aec91344870b504d936e837bea8
Autor:
José Seijas-Amigo, Maria José Mauriz-Montero, Pedro Suarez-Artime, Mónica Gayoso-Rey, Francisco Reyes-Santías, Ana Estany-Gestal, Antonia Casas-Martínez, Lara González-Freire, Ana Rodriguez-Vazquez, Natalia Pérez-Rodriguez, Laura Villaverde-Piñeiro, Concepción Castro-Rubinos, Esther Espino-Paisán, Octavio Cordova-Arevalo, Diego Rodriguez-Penas, Begoña Cardeso-Paredes, Marta Ribeiro-Ferreiro, Moisés Rodríguez-Mañero, Alberto Cordero, José R. González-Juanatey, MEMOGAL Investigators
Publikováno v:
Diseases, Vol 12, Iss 10, p 244 (2024)
The primary objective of this study was to conduct a cost–utility analysis of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors in real-world, comparing their use with standard care for managing cardiovascular disease. A multicenter
Externí odkaz:
https://doaj.org/article/5f7b5f76f0bb48bbbf874536a08de5ff
Autor:
Manuel Portolés, Emad Abu-Assi, Diego Rodríguez-Penas, Ana Mosquera-Leal, Beverly A. Rothermel, Valentina Parra, John Parrington, Sandra Feijóo-Bandín, Francisca Lago, Oreste Gualillo, Andrés Beiras, Esther Roselló-Lletí, José Ramón González-Juanatey, Vanessa García-Rúa, Joseph A. Hill, Luisa M. Seoane, Miguel Rivera, Pamela V. Lear
Publikováno v:
The Journal of Physiology. 594:3061-3077
Key points Two-pore channels (TPCs) were identified as a novel family of endolysosome-targeted calcium release channels gated by nicotinic acid adenine dinucleotide phosphate, as also as intracellular Na+ channels able to control endolysosomal fusion
Autor:
Ana Mosquera-Leal, Francisca Lago, Sandra Feijóo-Bandín, José Ramón González-Juanatey, Diego Rodríguez-Penas, Vanessa García-Rúa
Publikováno v:
Endocrine. 52:11-29
Nesfatin-1 is a new energy-regulating peptide widely expressed at both central and peripheral tissues with pleiotropic effects. In the last years, the study of nesfatin-1 actions and its possible implication in the development of different diseases h
Autor:
Alfonso Varela, José Ramón González-Juanatey, Oreste Gualillo, Diego Rodríguez-Penas, Darío Durán, Vanessa García-Rúa, Manuel Portolés, Francisca Lago, Carlos Dieguez, Sandra Feijóo-Bandín, Ana Mosquera-Leal, Miguel Rivera, Esther Roselló-Lletí
Publikováno v:
Cellular Physiology and Biochemistry, Vol 37, Iss 1, Pp 176-192 (2015)
Background: The adipokine chemerin has been associated with cardiovascular disease. We investigated the effects of chemerin on viability and intracellular signalling in murine cardiomyocytes, and the effects of insulin and TNF-α on cardiomyocyte che
Autor:
Esther Roselló-Lletí, Miguel Rivera, Vanessa García-Rúa, Diego Rodríguez-Penas, Ana Mosquera-Leal, Sandra Feijóo-Bandín, Manuel Portolés, Francisca Lago, Emad Abu-Assi, Carlos Dieguez, José Ramón González-Juanatey
Publikováno v:
Endocrine. 51:551-555
The appetite-regulating neuropeptide nesfatin-1 can influence cardiovascular function: in vivo analyses have shown that in rats it regulates blood pressure [1] and heart rate [2], and is cardioprotective against lesions from ischemia/reperfusion (I/
Autor:
F. Lago, Alana Aragón-Herrera, Diego Rodríguez-Penas, M. Rivera, José Ramón González-Juanatey, Manuel Portolés, Mario Bigazzi, Daniele Bani, Esther Roselló-Lletí, Oreste Gualillo, Sandra Feijóo-Bandín
Publikováno v:
Endocrine. 60(1)
Many evidences show that the hormone relaxin plays a pivotal role in the physiology and pathology of the cardiovascular system. This pleiotropic hormone exerts regulatory functions through specific receptors in cardiovascular tissues: in experimental