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Orthotopic Liver Transplantation in a Cirrhotic Patient With Recent COVID-19 Infection

Autor: Daniel Castaneda, Xaralambos Zervos, C. McWilliams, K. Al Khalloufi, K. T. Singh, Samer Ebaid, C. Donato, A. Pinna, Diego Reino, Adalberto Gonzalez

Publikováno v: ACG Case Reports Journal

The coronavirus disease 2019 (COVID-19) pandemic has led to a decrease in liver transplantation because of concerns regarding safety and healthcare resource utilization. There are scant data regarding the safety, optimal timing, and preferred postsur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfd2e0d37f83530b4840912e3ef40fbf
http://europepmc.org/articles/PMC8270595

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Transplantation of HCV Viremic Livers into HCV Viremic Recipients Followed by Direct-acting Antiviral Therapy

Autor: Xaralambos Zervos, Jason M. Vanatta, Andreas Tzakis, Nikhil Kapila, K. V. Narayanan Menon, Kawtar Al Khalloufi, Gianina Flocco, Samer Ebaid, Diego Reino, Christina C. Lindenmeyer

Publikováno v: Journal of Clinical and Translational Hepatology

Background and Aims: Hepatitis C virus (HCV)-infected organs are underutilized. We aimed to assess the safety and efficacy of direct-acting antiviral agents (DAAs) therapy in HCV viremic patients who are transplanted with a liver from a HCV viremic d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e73fd0fdd31fd23861d81a90441d953f
https://doi.org/10.14218/jcth.2019.00014

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Hepatitis C Virus NAT-Positive Solid Organ Allografts Transplanted Into Hepatitis C Virus-Negative Recipients: A Real-World Experience

Autor: Joshua J. Shaw, Xaralambos Zervos, Salwa Rhazouani, Cristiano Quintini, Nikhil Kapila, Kawtar Al-Khalloufi, Neerja Agrawal, Viviana Navas, Carla Murgas, Diego Reino, K. V. Narayanan Menon, Christina C. Lindenmeyer, Michael Castillo, Asad Ur Rahman, Jason M. Vanatta, Samer Ebaid, Cedric Sheffield, Charles Miller

Publikováno v: Hepatology (Baltimore, Md.)References. 72(1)

Background and aims Hepatitis C virus (HCV)-viremic organs are underutilized, and there is limited real-world experience on the transplantation of HCV-viremic solid organs into recipients who are HCV negative. Approach and results Patients listed or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cfb790e3848f82962a5780c6223abb3
https://pubmed.ncbi.nlm.nih.gov/32064641

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Early Trauma-Hemorrhage–Induced Splenic and Thymic Apoptosis Is Gut-Mediated and Toll-Like Receptor 4-Dependent

Autor: Jacquelyn N. Tomaio, Edwin A. Deitch, Leonard Mason, David Palange, Gregory Tiesi, Diego Reino

Publikováno v: Shock. 39:507-513

Immune depression after trauma-hemorrhage has been implicated as an important factor in the pathogenesis of sepsis and septic-organ failure. Although recent studies have implicated immune-cell apoptosis as an important factor in the evolution of this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e0ee18a19bd216dd72023adcfc608aff
https://doi.org/10.1097/shk.0b013e318293d020

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Activation of Toll-Like Receptor 4 Is Necessary for Trauma Hemorrhagic Shock-Induced Gut Injury and Polymorphonuclear Neutrophil Priming

Autor: Qi Lu, Sharvil U. Sheth, Rena Feinman, Edwin A. Deitch, Luis Ulloa, Antonio De Maio, Robert P. Bonitz, Diego Reino, Da Zhong Xu, David Palange, Geber Peña, Elenora Feketeova

Publikováno v: Shock. 38:107-114

Interactions of toll-like receptors (TLRs) with nonmicrobial factors play a major role in the pathogenesis of early trauma-hemorrhagic shock (T/HS)-induced organ injury and inflammation. Thus, we tested the hypothesis that TLR4 mutant (TLR4 mut) mice

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6e20e008871852a34bdb0f7c3f2544ce
https://doi.org/10.1097/shk.0b013e318257123a

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Hypoxia-inducible factor plays a gut-injurious role in intestinal ischemia reperfusion injury

Autor: Rena Feinman, Billy Abungu, Iriana Colorado, Kolenkode B. Kannan, Edwin A. Deitch, Gregg L. Semenza, Anthony C. Watkins, Xiaofa Qin, Qi Lu, Diego Reino, David Palange, Da-Zhong Xu, Francis J. Caputo

Publikováno v: American Journal of Physiology-Gastrointestinal and Liver Physiology. 300:G853-G861

Gut injury and loss of normal intestinal barrier function are key elements in the paradigm of gut-origin systemic inflammatory response syndrome, acute lung injury, and multiple organ dysfunction syndrome (MODS). As hypoxia-inducible factor (HIF-1) i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e281074ce75f73426dc6bee2c83caa76
https://doi.org/10.1152/ajpgi.00459.2010

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Testosterone depletion / blockade in male rats protects against trauma hemorrhagic shock-induced distant organ injury by limiting gut injury and subsequent production of biologically active mesenteric lymph

Autor: Da-Zhong Xu, Edwin A. Deitch, Eleonora Feketeova, Qi Lu, Xiaofa Qin, Dong Wei, David Palange, Diego Reino, Sharvil U. Sheth

Background We tested the hypothesis that testosterone depletion or blockade in male rats protects against trauma hemorrhagic shock-induced distant organ injury by limiting gut injury and subsequent production of biologically active mesenteric lymph.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1444b2c84c511908dd831c76d36e6c14
https://europepmc.org/articles/PMC3269763/

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