Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Diego Prada‐Gracia"'
Autor:
Maryangel Perea‐Cabrera, Javier T. Granados‐Riveron, Begoña Segura‐Stanford, Liliana M. Moreno‐Vargas, Diego Prada‐Gracia, Mari C. Moran‐Espinosa, Julio Erdmenger, Hector Diaz‐Garcia, Rocío Sánchez‐Urbina
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 11, Iss 9, Pp n/a-n/a (2023)
Abstract Background Opitz GBBB syndrome (GBBB) is an X‐linked disease characterized by midline defects, including congenital heart defects. We present our diagnostic approach to the identification of GBBB in a consanguineous family in which two mal
Externí odkaz:
https://doaj.org/article/ff3b89a49b444ee885443b6b405fec54
Autor:
Luis Fernando Cofas-Vargas, Paola Mendoza-Espinosa, Luis Pablo Avila-Barrientos, Diego Prada-Gracia, Héctor Riveros-Rosas, Enrique García-Hernández
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
In addition to playing a central role in the mitochondria as the main producer of ATP, FOF1-ATP synthase performs diverse key regulatory functions in the cell membrane. Its malfunction has been linked to a growing number of human diseases, including
Externí odkaz:
https://doaj.org/article/17d8a8ce8039438493a490a74edf5cf5
Autor:
Armando Alfredo Mateos-Chávez, Paola Muñoz-López, Elayne Irene Becerra-Báez, Luis Fernando Flores-Martínez, Diego Prada-Gracia, Liliana Marisol Moreno-Vargas, Guillermina Juliana Baay-Guzmán, Uriel Juárez-Hernández, Bibiana Chávez-Munguía, Lourdes Cabrera-Muñóz, Rosendo Luria-Pérez
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The survival of patients with non-Hodgkin's lymphoma (NHL) has substantially improved with current treatments. Nevertheless, the appearance of drug-resistant cancer cells leads to patient relapse. It is therefore necessary to find new antitumor thera
Externí odkaz:
https://doaj.org/article/b932eb9986744e69aac45f05c432c757
Autor:
Leonardo David Herrera-Zúñiga, Liliana Marisol Moreno‑Vargas, Luck Ballaud, José Correa‑Basurto, Diego Prada‑Gracia, David Pastré, Patrick A. Curmi, Jean Michel Arrang, Rachid C. Maroun
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/cbc64935928949fa9a25b5ea8739d205
Autor:
K. Eurídice Juárez-Mercado, Fernando D. Prieto-Martínez, Norberto Sánchez-Cruz, Andrea Peña-Castillo, Diego Prada-Gracia, José L. Medina-Franco
Publikováno v:
Pharmaceuticals, Vol 14, Iss 1, p 17 (2020)
Inhibitors of DNA methyltransferases (DNMTs) are attractive compounds for epigenetic drug discovery. They are also chemical tools to understand the biochemistry of epigenetic processes. Herein, we report five distinct inhibitors of DNMT1 characterize
Externí odkaz:
https://doaj.org/article/ff9ba157e1bc430ab833685f1da9661b
Publikováno v:
Boletín Médico del Hospital Infantil de México, Vol 73, Iss 6, Pp 424-431 (2016)
The efficiency and the propensity of a drug to be bound to its target protein have been inseparable concepts for decades now. The correlation between the pharmacological activity and the binding affinity has been the first rule to design and optimize
Externí odkaz:
https://doaj.org/article/934fd89df13741a5b4f1ac18a8b65284
Publikováno v:
Boletín Médico del Hospital Infantil de México, Vol 73, Iss 6, Pp 411-423 (2016)
Developing a novel drug is a complex, risky, expensive and time-consuming venture. It is estimated that the conventional drug discovery process ending with a new medicine ready for the market can take up to 15 years and more than a billion USD. Fortu
Externí odkaz:
https://doaj.org/article/298cc5fb79cc43bfaa4f728331f9f17e
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 12, p e1005240 (2016)
The lipid composition of cell membranes has increasingly been recognized as playing an important role in the function of various membrane proteins, including G Protein-Coupled Receptors (GPCRs). For instance, experimental and computational evidence h
Externí odkaz:
https://doaj.org/article/7f1981f7123d4712a3127da5c83e1118
Publikováno v:
PLoS Computational Biology, Vol 5, Iss 6, p e1000415 (2009)
Knowledge of the Free Energy Landscape topology is the essential key to understanding many biochemical processes. The determination of the conformers of a protein and their basins of attraction takes a central role for studying molecular isomerizatio
Externí odkaz:
https://doaj.org/article/9eb7a5b9d8b840cab2db554ab8e8c209
Autor:
Norberto Sánchez-Cruz, Fernando D. Prieto-Martínez, K. Eurídice Juárez-Mercado, José L. Medina-Franco, Diego Prada-Gracia, Andrea Peña-Castillo
Publikováno v:
Pharmaceuticals
Pharmaceuticals, Vol 14, Iss 17, p 17 (2021)
Volume 14
Issue 1
Pharmaceuticals, Vol 14, Iss 17, p 17 (2021)
Volume 14
Issue 1
Inhibitors of DNA methyltransferases (DNMTs) are attractive compounds for epigenetic drug discovery. They are also chemical tools to understand the biochemistry of epigenetic processes. Herein, we report five distinct inhibitors of DNMT1 characterize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ad78750dd23642890e63ff31ac49f7e
https://pubmed.ncbi.nlm.nih.gov/33375520
https://pubmed.ncbi.nlm.nih.gov/33375520