Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Diego Paine"'
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
BackgroundHepatocyte nuclear factor 4 alpha (HNF4α) is the master regulator of hepatic differentiation. Recent studies have also revealed the role of HNF4α in hepatocyte proliferation via negatively regulating the expression of proto-mitogenic gene
Externí odkaz:
https://doaj.org/article/aac9269bc8e24f43a2f589beecdc3d06
Autor:
Diego Paine‐Cabrera, Lisa K. Harvey, Dakota R. Robarts, Michele T. Pritchard, John Thyfault, Steven A. Weinman, Udayan Apte, Voytek Slowik
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 12, Pp 2719-2728 (2023)
Abstract Non‐alcoholic fatty liver disease (NAFLD), newly renamed metabolic dysfunction‐associated liver disease (MASLD), is a leading cause of liver disease in children and adults. There is a paucity of data surrounding potential biomarkers and
Externí odkaz:
https://doaj.org/article/5f10513adf2048eea5c613c1608d2926
Publikováno v:
Livers, Vol 3, Iss 3, Pp 331-346 (2023)
Congenital hepatic fibrosis/Autosomal recessive polycystic kidney disease (CHF/ARPKD) is an inherited neonatal disease induced by mutations in the PKHD1 gene and characterized by cysts and robust pericystic fibrosis in the liver and kidneys. The PCK
Externí odkaz:
https://doaj.org/article/8573c72cabd44c818e49c336e22ee0af
Autor:
Alvaro Santibañez, Diego Paine, Mick Parra, Carlos Muñoz, Natalia Valdes, Claudia Zapata, Rodrigo Vargas, Alex Gonzalez, Mario Tello
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Lactic acid bacteria are a powerful vehicle for releasing of cytokines and immunostimulant peptides at the gastrointestinal level after oral administration. However, its therapeutic application against pathogens that affect rainbow trout and Atlantic
Externí odkaz:
https://doaj.org/article/d6aac0cfdbe44bb28e6c4175b3252215
Autor:
Manasi Kotulkar, Diego Paine-Cabrera, Sarah Abernathy, Dakota R. Robarts, Wendena S. Parkes, Kristi Lin- Rahardja, September Numata, Margitta Lebofsky, Hartmut Jaeschke, Udayan Apte
Publikováno v:
Hepatology.
Autor:
Dakota R. Robarts, Manasi Kotulkar, Diego Paine-Cabrera, Kaitlyn K. Venneman, John A. Hanover, Natasha E. Zachara, Chad Slawson, Udayan Apte
Publikováno v:
bioRxiv
Background & AimsO-GlcNAcylation is a post-translational modification catalyzed by the enzyme O-GlcNAc transferase (OGT), which transfers a single N-acetylglucosamine sugar from UDP-GlcNAc to the protein on serine and threonine residues on proteins.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbb38b02c1e8d5f7edc4c75180901618
https://doi.org/10.1101/2023.02.16.528884
https://doi.org/10.1101/2023.02.16.528884
Autor:
Dakota R. Robarts, Diego Paine-Cabrera, Manasi Kotulkar, Kaitlyn K. Venneman, Sumedha Gunewardena, J. Christopher Corton, Christopher Lau, Lander Foquet, Greg Bial, Udayan Apte
Publikováno v:
bioRxiv
BackgroundPer- and polyfluoroalkyl substances (PFAS) are persistent organic pollutants with myriad adverse effects. While perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) are the most common contaminants, levels of replacement P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91522a930899b3dc563f0a14e60874ba
https://europepmc.org/articles/PMC9915685/
https://europepmc.org/articles/PMC9915685/
Publikováno v:
bioRxiv
Congenital hepatic fibrosis / Autosomal recessive polycystic kidney disease (CHF/ARPKD) is an inherited neonatal disease induced by mutations in thePKHD1gene and characterized by cysts, and robust pericystic fibrosis in liver and kidney. The PCK rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e8149f6cb93754645f4642d2c01ee1e
https://europepmc.org/articles/PMC9882327/
https://europepmc.org/articles/PMC9882327/
Autor:
Michael W. Manley, Hartmut Jaeschke, Bharat Bhushan, Diego Paine Cabrera, Udayan Apte, Samikshya Poudel, Sumedha Gunewardena
Publikováno v:
Toxicol Sci
Overdose of acetaminophen (APAP) is the major cause of acute liver failure (ALF) in the Western world with very limited treatment options. Previous studies from our groups and others have shown that timely activation of liver regeneration is a critic
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