Pharmacokinetics and safety of brivaracetam in neonates with repeated electroencephalographic seizures: A multicenter, open‐label, single‐arm study

Autor: Ronit Pressler, Geraldine Boylan, Eugene Dempsey, Kerstin Alexandra Klotz, Walter Krauwinkel, Edgar Will, Diego Morita, Florin Floricel, Jan‐Peer Elshoff, John van denAnker

Publikováno v: Epilepsia Open, Vol 9, Iss 2, Pp 522-533 (2024)

Abstract Objective To evaluate the pharmacokinetics (PK), safety, and tolerability of brivaracetam (BRV) in neonates with repeated electroencephalographic seizures not controlled with previous antiseizure medications (ASMs). Methods Phase 2/3, multic

Externí odkaz: https://doaj.org/article/8137ef2a8dbb4c9a914a2a6bdb5fe170

Incorporation versus coating of antimicrobials in polymethylmethacrylate: A systematic review

Autor: Da Costa, Diego Morita Gomes, Ferreira, Izabela, Reis, Andréa Cândido Dos

The modification of polymethylmethacrylate will confer antimicrobial resistance to the material and the method of modification, incorporation or coating, can influence the antimicrobial action. The objective of this study is to answer the question "A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bfe6e303427ac836ae549e66efd53569

Changes in functional organization and functional connectivity during story listening in children with benign childhood epilepsy with centro-temporal spikes

Autor: Scott K. Holland, Mekibib Altaye, Thomas Maloney, Jerzy P. Szaflarski, Anna W. Byars, Jeffrey R. Tenney, Jennifer Vannest, Tracy A. Glauser, Diego Morita

Publikováno v: Brain Lang

Children with Benign Epilepsy with Centrotemporal Spikes (BECTS), despite high likelihood for seizure remission, are reported to have subtle difficulties in language and other cognitive skills. We used functional MRI and a story listening task to exa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47f920d8017d60f9d159e13e2932f0a1
https://doi.org/10.1016/j.bandl.2017.01.009

Methodological Issues in Predicting Pediatric Epilepsy Surgery Candidates Through Natural Language Processing and Machine Learning

Autor: Katherine Holland-Bouley, Diego Morita, Francesco T. Mangano, Tracy A. Glauser, Shannon M. Standridge, Robert Faist, Benjamin Glass, Ravindra Arya, Kevin Bretonnel Cohen, John Pestian, Brian Connolly, Hansel M. Greiner

Publikováno v: Biomedical Informatics Insights, Vol 2016, Iss 8, Pp 11-18 (2016)
Biomedical Informatics Insights, Vol 8 (2016)
Biomedical Informatics Insights

Objective: We describe the development and evaluation of a system that uses machine learning and natural language processing techniques to identify potential candidates for surgical intervention for drug-resistant pediatric epilepsy. The data are com

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2364000567c8c669b63a7fb5e4b7b0ae
http://www.la-press.com/methodological-issues-in-predicting-pediatric-epilepsy-surgery-candida-article-a5640

Quality improvement in neurology: Child neurology quality measure set: Executive summary

Autor: Erin Lee, Gogi Kumar, Christina L. Szperka, Erin Day Fecske, Sanjeev V. Kothare, Tim Feyma, Anup D. Patel, Anne T. Berg, Lori Billinghurst, Zachary M. Grinspan, Ann Yeh, Amy J. Houtrow, Migvis Monduy, Jeffrey Buchhalter, Daniel Fain, M. Cristina Victorio, Diego Morita

Publikováno v: Neurology. 90(2)

Childhood neurologic disorders, as a group, include relatively common conditions such as migraine (prevalence between 3% and 10.6% in children 3–15 years of age1,2), transient tic disorders (TDs) (3%),3 and specifically Tourette syndrome (TS) (0.8%

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f12810fab723305d5c28682bb81395be
https://pubmed.ncbi.nlm.nih.gov/29247076