Výsledky vyhledávání - "Diego Martinez vasquez"

Mineralocorticoid Receptor Antagonist Reduces Renal Injury in Rodent Models of Types 1 and 2 Diabetes Mellitus

Autor: Maria F. Toniolo, Tham M. Yao, Vincent Ricchiuti, Gordon H. Williams, Luminita H. Pojoga, Eveline Oestreicher, Christine Guo, Nathalie Lapointe, Diego Martinez-Vasquez, Gail K. Adler, Taisuke Kikuchi, Gonzalo P. Mendez

Publikováno v: Endocrinology. 147:5363-5373

To determine whether mineralocorticoid receptor (MR) activation plays a role in diabetic renal injury and whether this role differs in types 1 and 2 diabetes mellitus, we examined the effect of a MR antagonist on renal injury in rodent models of type

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fd27d11b3fe09cfa8725601e3cbd2d7
https://doi.org/10.1210/en.2006-0944

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Aldosterone and Not Plasminogen Activator Inhibitor-1 Is a Critical Mediator of Early Angiotensin II/ N G -Nitro- l -Arginine Methyl Ester-Induced Myocardial Injury

Autor: Gail K. Adler, James R. Stone, Diego Martinez-Vasquez, Weranuj Roubsanthisuk, Larus Jonasson, Eveline Oestreicher, Koji Mukasa

Publikováno v: Circulation. 108:2517-2523

Background— Angiotensin II (Ang II) increases levels of aldosterone and plasminogen activator inhibitor-1 (PAI-1). Both aldosterone and PAI-1 seem to promote cardiovascular (CV) injury. Our objective was to determine the roles of PAI-1 and aldoster

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8a005884b9c08ba4f769a9c828da11d
https://doi.org/10.1161/01.cir.0000097000.51723.6f

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Estradiol increases proteinuria and angiotensin II type 1 receptor in kidneys of rats receiving L-NAME and angiotensin II

Autor: Diego Martinez-Vasquez, Weranuj Roubsanthisuk, Gail K. Adler, L. Jonasson, D. Burr, Christine Guo, Ellen W. Seely, Tham M. Yao, Eveline Oestreicher, T. Kikuchi, Sonia R. Mayoral, Vincent Ricchiuti

Publikováno v: Kidney international. 70(10)

Prospective, placebo-controlled clinical trials suggest that estrogen may have adverse effects on the vascular system in women. The goal of this study was to determine if 17beta-estradiol (E2) would have adverse effects on the renovasculature in a ra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfb80824f944031350d7c7ee8dd44333
https://pubmed.ncbi.nlm.nih.gov/17021606

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Mineralocorticoid Receptor Activation by Aldosterone or Corticosterone Induces Hypertension, Myocardial Infarction and Proteinuria

Autor: Qing-Feng Tao, Diego Martinez vasquez, Ricardo Rocha, Gordon H Williams, Gail K Adler

Publikováno v: Hypertension. 36:723-723

P165 Aldosterone through its interaction with the mineralocorticoid receptor (MR) plays a critical role in the development of hypertension and cardiovascular injury (CVI). Normally, MR is protected by 11β-hydroxysteroid dehydrogenase (11β-HSD) whic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::412b3a00efe9cc01c592e0a867a834c4
https://doi.org/10.1161/hyp.36.suppl_1.723-a

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