Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Diego M Marzese"'
Autor:
Rolando Ruiz, Sohail Jahid, Melissa Harris, Diego M Marzese, Francisco Espitia, Priya Vasudeva, Chi-Fen Chen, Sebastien de Feraudy, Jie Wu, Daniel L Gillen, Tatiana B Krasieva, Bruce J Tromberg, William J Pavan, Dave S Hoon, Anand K Ganesan
Publikováno v:
PLoS Genetics, Vol 13, Iss 7, p e1006913 (2017)
Genes and pathways that allow cells to cope with oncogene-induced stress represent selective cancer therapeutic targets that remain largely undiscovered. In this study, we identify a RhoJ signaling pathway that is a selective therapeutic target for B
Externí odkaz:
https://doaj.org/article/582d4bd0a5b74af2839786a23753eee3
Autor:
Pere Llinàs-Arias, Miquel Ensenyat-Méndez, Javier I. J. Orozco, Sandra Íñiguez-Muñoz, Betsy Valdez, Chuan Wang, Anja Mezger, Eunkyoung Choi, Yan Zhou Tran, Liqun Yao, Franziska Bonath, Remi-André Olsen, Mattias Ormestad, Manel Esteller, Mathieu Lupien, Diego M. Marzese
Publikováno v:
BMC Genomic Data, Vol 24, Iss 1, Pp 1-7 (2023)
Abstract Objectives Triple-negative breast cancer (TNBC) is a highly aggressive breast cancer subtype with limited treatment options. Unlike other breast cancer subtypes, the scarcity of specific therapies and greater frequencies of distant metastase
Externí odkaz:
https://doaj.org/article/ae6de6960e06403498b0edcc6089e71b
Autor:
Pere Llinàs-Arias, Miquel Ensenyat-Mendez, Sandra Íñiguez-Muñoz, Javier I. J. Orozco, Betsy Valdez, Matthew P. Salomon, Chikako Matsuba, Maria Solivellas-Pieras, Andrés F. Bedoya-López, Borja Sesé, Anja Mezger, Mattias Ormestad, Fernando Unzueta, Siri H. Strand, Alexander D. Boiko, E Shelley Hwang, Javier Cortés, Maggie L. DiNome, Manel Esteller, Mathieu Lupien, Diego M. Marzese
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-14 (2023)
Abstract Background Triple-negative breast cancer (TNBC) is an aggressive subtype that exhibits a high incidence of distant metastases and lacks targeted therapeutic options. Here we explored how the epigenome contributes to matrix metalloprotease (M
Externí odkaz:
https://doaj.org/article/b71cb755354f404e9aa916bdd4c51c9e
Autor:
Miquel Ensenyat-Mendez, Javier I. J. Orozco, Pere Llinàs-Arias, Sandra Íñiguez-Muñoz, Jennifer L. Baker, Matthew P. Salomon, Mercè Martí, Maggie L. DiNome, Javier Cortés, Diego M. Marzese
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-8 (2023)
Abstract Background Immune checkpoint inhibitors (ICI) improve clinical outcomes in triple-negative breast cancer (TNBC) patients. However, a subset of patients does not respond to treatment. Biomarkers that show ICI predictive potential in other sol
Externí odkaz:
https://doaj.org/article/1f2057e671df4541b19b7339086d3e98
Autor:
Borja Sesé, Sandra Íñiguez-Muñoz, Miquel Ensenyat-Mendez, Pere Llinàs-Arias, Guillem Ramis, Javier I. J. Orozco, Silvia Fernández de Mattos, Priam Villalonga, Diego M. Marzese
Publikováno v:
Cancers, Vol 14, Iss 9, p 2070 (2022)
Background: Glioma stem cells (GSCs) have self-renewal and tumor-initiating capacities involved in drug resistance and immune evasion mechanisms in glioblastoma (GBM). Methods: Core-GSCs (c-GSCs) were identified by selecting cells co-expressing high
Externí odkaz:
https://doaj.org/article/7fa4a3cd750e44298984b42620ed14f1
Autor:
Javier I. J. Orozco, Julie Le, Miquel Ensenyat-Mendez, Jennifer L. Baker, Joanne Weidhaas, Alexandra Klomhaus, Diego M. Marzese, Maggie L. DiNome
Publikováno v:
Annals of Surgical Oncology. 29:6407-6414
Autor:
Dave S.B. Hoon, Michael A. Davies, Gordon B. Mills, Yelena Kravtsova-Ivantsiv, Nellie Nelson, Sandy Hsu, Stella Lam, Kevin Tran, Matthew P. Salomon, Jinhua Wang, Shigeshi Ono, Matias Bustos, Keisuke Hata, Diego M. Marzese, Aaron Ciechanover, Yuuki Iida
TIFF file for supplementary figure S3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::676ac09c1298ef5f04cd884f84a45f4d
https://doi.org/10.1158/1078-0432.22462418
https://doi.org/10.1158/1078-0432.22462418
Autor:
Dave S.B. Hoon, Michael A. Davies, Gordon B. Mills, Yelena Kravtsova-Ivantsiv, Nellie Nelson, Sandy Hsu, Stella Lam, Kevin Tran, Matthew P. Salomon, Jinhua Wang, Shigeshi Ono, Matias Bustos, Keisuke Hata, Diego M. Marzese, Aaron Ciechanover, Yuuki Iida
Purpose: Abnormal activation of the NF-κB pathway induces a more aggressive phenotype of cutaneous melanoma. Understanding the mechanisms involved in melanoma NF-κB activation may identify novel targets for this pathway. KPC1, an E3 ubiquitin ligas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0487403ff43ecebd71ca5af4e3d748d
https://doi.org/10.1158/1078-0432.c.6525098.v1
https://doi.org/10.1158/1078-0432.c.6525098.v1
Autor:
Dave S.B. Hoon, Michael A. Davies, Gordon B. Mills, Yelena Kravtsova-Ivantsiv, Nellie Nelson, Sandy Hsu, Stella Lam, Kevin Tran, Matthew P. Salomon, Jinhua Wang, Shigeshi Ono, Matias Bustos, Keisuke Hata, Diego M. Marzese, Aaron Ciechanover, Yuuki Iida
The file contains Supplementary Table S1 and figure legends for Supplementary Figure S1 to S4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09dce45b1f3c522349c50a7bdcd5408b
https://doi.org/10.1158/1078-0432.22462412
https://doi.org/10.1158/1078-0432.22462412
Autor:
Dave S.B. Hoon, Daniel F. Kelly, Garni Barkhoudarian, Bernard A. Fox, Carmen Ballesteros-Merino, Yuki Takasumi, Chikako Matsuba, Xin Zhang, Nellie Nelson, Sandy C. Hsu, Diego M. Marzese, Xiaowen Wang, Matthew P. Salomon
GH-secreting PAs starburst plot gene details. The top 50 most significantly differentially expressed genes contained within Figure 5 for GH-secreting PAs as compared to endocrine-inactive PAs. The table has five columns; 1) gene symbol, 2) Entrez ID
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::270edaf3788579fc33a4d4095576f9d2
https://doi.org/10.1158/1078-0432.22464266.v1
https://doi.org/10.1158/1078-0432.22464266.v1