Optimal large‐scale CD34+ enrichment from a leukapheresis collection using the clinimacs prodigy platform

Autor: Oscar M. Pello, Diego Lanzarot, Mercedes Colorado, Cristina Amunarriz, Andrés Insunza, Lorena Álvarez‐Rodríguez, María Díez de Velasco, Natividad Sainz‐Sainz, José Luis Arroyo

Publikováno v: Clinical Case Reports, Vol 8, Iss 12, Pp 2650-2653 (2020)

Abstract Optimization of Hematology Patient's treatment: It is possible to obtain a 100% CD34+ recovery after CD34+ selection using the CliniMACS Prodigy.

Externí odkaz: https://doaj.org/article/852b13bf86bc428fb51e8993523a3298

GMP-Compliant Manufacturing of NKG2D CAR Memory T Cells Using CliniMACS Prodigy

Autor: Lucía Fernández, Adrián Fernández, Isabel Mirones, Adela Escudero, Leila Cardoso, María Vela, Diego Lanzarot, Raquel de Paz, Alejandra Leivas, Miguel Gallardo, Antonio Marcos, Ana Belén Romero, Joaquín Martínez-López, Antonio Pérez-Martínez

Publikováno v: Frontiers in Immunology, Vol 10 (2019)

Natural killer group 2D (NKG2D) is a natural killer (NK) cell-activating receptor that recognizes different stress-induced ligands that are overexpressed in a variety of childhood and adult tumors. NKG2D chimeric antigen receptor (CAR) T cells have s

Externí odkaz: https://doaj.org/article/ba4d2ea6112c49d98f6f8eef30f4f95d

Optimizing the procedure to manufacture clinical‐grade NK cells for adoptive immunotherapy

Autor: Lucía Fernández, Alfonso Navarro-Zapata, Cristina Ferreras, Diego Lanzarot, Alicia Pernas, Carlos Rodriguez-Antolin, Alejandra Leivas, Marta Cobo, Aurora Viejo, Joaquín Martínez, Gema Casado, Beatriz Ruz-Caracuel, Carmen Mestre, María Vela, Adela Escudero, Isabel Mirones, Nerea Matamala, Adrián Fernández, Antonio Pérez-Martínez

Publikováno v: Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Cancers
Volume 13
Issue 3
Cancers, Vol 13, Iss 577, p 577 (2021)
Universitat Autònoma de Barcelona

Natural killer (NK) cells represent promising tools for cancer immunotherapy. We report the optimization of an NK cell activation–expansion process and its validation on clinical‐scale. Methods: RPMI‐1640, stem cell growth medium (SCGM), NK MAC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81a550745a88bb61d650bdae1559978c
https://doi.org/10.3390/cancers13030577

Optimal large‐scale CD34+ enrichment from a leukapheresis collection using the clinimacs prodigy platform.

Autor: Pello, Oscar M.^1,2 (AUTHOR) oscar.pello@bscan.org, Lanzarot, Diego³ (AUTHOR), Colorado, Mercedes^2,4 (AUTHOR), Amunarriz, Cristina^1,2 (AUTHOR), Insunza, Andrés^2,4 (AUTHOR), Álvarez‐Rodríguez, Lorena^1,2 (AUTHOR), Díez de Velasco, María¹ (AUTHOR), Sainz‐Sainz, Natividad¹ (AUTHOR), Arroyo, José Luis^1,2 (AUTHOR) director@bscan.org

Publikováno v: Clinical Case Reports. Dec2020, Vol. 8 Issue 12, p2650-2653. 4p.

Isolation of Functional SARS-CoV-2 Antigen-Specific T-Cells with Specific Viral Cytotoxic Activity for Adoptive Therapy of COVID-19.

Autor: García-Ríos, Estéfani, Leivas, Alejandra, Mancebo, Francisco J., Sánchez-Vega, Laura, Lanzarot, Diego, Aguado, José María, Martínez-López, Joaquín, Paciello, María Liz, Pérez-Romero, Pilar

Publikováno v: Biomedicines; Mar2022, Vol. 10 Issue 3, p630, 14p