Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Diego La Mendola"'
Autor:
Antonio Magrì, Barbara Tomasello, Irina Naletova, Giovanni Tabbì, Warren R. L. Cairns, Valentina Greco, Sebastiano Sciuto, Diego La Mendola, Enrico Rizzarelli
Publikováno v:
Biomolecules, Vol 14, Iss 9, p 1104 (2024)
A low level of Neurotrophins (NTs), their Tyrosine Kinase Receptors (Trks), Vascular Endothelial Growth Factors (VEGFs) and their receptors, mainly VEGFR1 and VEGFR2, characterizes AD brains. The use of NTs and VEGFs as drugs presents different issue
Externí odkaz:
https://doaj.org/article/c00511307d7247e288aaa9fd96d62597
Publikováno v:
Molecules, Vol 28, Iss 20, p 7064 (2023)
In typical protein–nanoparticle surface interactions, the biomolecule surface binding and consequent conformational changes are intermingled with each other and are pivotal to the multiple functional properties of the resulting hybrid bioengineered
Externí odkaz:
https://doaj.org/article/a76747a3987c42ddb8eda300d9829fcf
Publikováno v:
Membranes, Vol 13, Iss 5, p 489 (2023)
Neurotrophins (NTs), which are crucial for the functioning of the nervous system, are also known to regulate vascularization. Graphene-based materials may drive neural growth and differentiation, and, thus, have great potential in regenerative medici
Externí odkaz:
https://doaj.org/article/6f9c2dd8a6c74eeb9ea3e85d2c0d7093
Autor:
Lorenzo Riela, Lorena Maria Cucci, Örjan Hansson, Tiziano Marzo, Diego La Mendola, Cristina Satriano
Publikováno v:
Inorganics, Vol 10, Iss 11, p 188 (2022)
Graphene oxide (GO) nanosheets with different content in the defective carbon species bound to oxygen sp3 were functionalized with the angiogenin (ANG) protein, to create a novel nanomedicine for modulating angiogenic processes in cancer therapies. T
Externí odkaz:
https://doaj.org/article/13268cfbb80f4a1498a5d8312ab8168e
Autor:
Lorenzo Chiaverini, Alessandro Pratesi, Damiano Cirri, Arianna Nardinocchi, Iogann Tolbatov, Alessandro Marrone, Mariagrazia Di Luca, Tiziano Marzo, Diego La Mendola
Publikováno v:
Molecules, Vol 27, Iss 8, p 2578 (2022)
Auranofin (AF, hereafter) is an orally administered chrysotherapeutic agent approved for the treatment of rheumatoid arthritis that is being repurposed for various indications including bacterial infections. Its likely mode of action involves the imp
Externí odkaz:
https://doaj.org/article/6550c009dca54cbda020e06527a74ef8
Autor:
Iogann Tolbatov, Elisabetta Barresi, Sabrina Taliani, Diego La Mendola, Tiziano Marzo, Alessandro Marrone
Publikováno v:
Inorganic Chemistry Frontiers. 10:2226-2238
Diruthenium(ii,iii) paddlewheel carboxylates combine the pharmacological properties of the dimetallic center with those ascribed to the μ-bridged carboxylates, thus leading to novel, dual-acting anticancer metallodrugs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68898d73d9450e5277d8aa820f462be8
https://doi.org/10.1039/d3qi00157a
https://doi.org/10.1039/d3qi00157a
Autor:
Iogann Tolbatov, Damiano Cirri, Lorella Marchetti, Alessandro Marrone, Cecilia Coletti, Nazzareno Re, Diego La Mendola, Luigi Messori, Tiziano Marzo, Chiara Gabbiani, Alessandro Pratesi
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
Au(PEt3)I (AF-I hereafter), the iodide analog of the FDA-approved drug auranofin (AF hereafter), is a promising anticancer agent that produces its pharmacological effects through interaction with non-genomic targets such as the thioredoxin reductase
Externí odkaz:
https://doaj.org/article/80d53dd7b0e24fbabdfa02fc233254b9
Autor:
Giuseppe Trapani, Viviana Carmela Linda Caruso, Lorena Maria Cucci, Francesco Attanasio, Giovanni Tabbì, Giuseppe Forte, Diego La Mendola, Cristina Satriano
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Engineered graphene-based derivatives are attractive and promising candidates for nanomedicine applications because of their versatility as 2D nanomaterials. However, the safe application of these materials needs to solve the still unanswered issue o
Externí odkaz:
https://doaj.org/article/f7271b59e4014408b11527361c59b1e5
Autor:
Patrizia Di Pietro, Stefania Zimbone, Giulia Grasso, Diego La Mendola, Damien Cossement, Rony Snyders, Cristina Satriano
Publikováno v:
Applied Sciences, Vol 11, Iss 14, p 6333 (2021)
In this work, nanobiohybrids of plasmonic gold nanoparticles (AuNP, anti-angiogenic) and a peptide mimicking the vascular endothelial growth factor (VEGF, pro-angiogenic) were assembled and scrutinized in terms of physicochemical characterization, in
Externí odkaz:
https://doaj.org/article/07b042e479e64de8ac0305c34a4e75ac
Autor:
Patrizia Di Pietro, Nunzia Caporarello, Carmelina D. Anfuso, Gabriella Lupo, Antonio Magrì, Diego La Mendola, Cristina Satriano
Publikováno v:
ACS Omega, Vol 2, Iss 8, Pp 4071-4079 (2017)
Externí odkaz:
https://doaj.org/article/063836f7d90b4195a54d82a6f82740d0