Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Diego Javier Obiol"'
Autor:
Yagamare Fall, Diego Javier Obiol, Generosa Gómez, Eliana Noelia Alonso, Maria Marta Facchinetti, Mario Alfredo Quevedo, María Julia Ferronato, Andrea Martínez, Silvina Mariela Grioli, Alejandro Carlos Curino
The active form of vitamin D3, calcitriol, is a potent antiproliferative compound. However, when effective antitumor doses of calcitriol are used, hypercalcemic effects are observed, thus blocking its therapeutic application. To overcome this problem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0125fb5e0309b464d55547d1a0972b62
Wiley Online Library
Wiley Online Library
Autor:
Diego Javier Obiol, Marilina Mascaró, Silvina Mariela Grioli, Yagamare Fall, Maria Marta Facchinetti, Marcos L. Rivadulla, Mario Alfredo Quevedo, Eliana Noelia Alonso, Generosa Gómez, María Julia Ferronato, Andrea Martínez, Josefina Alejandra Guevara, Alejandro Carlos Curino
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Calcitriol analogs have shown promising potential as compounds to be used in cancer chemotherapy. This report presents the synthesis of a novel vitamin D3 derivative with an amide and a carboxyl group in its side chain, called ML-344. In addition, we
Autor:
Maria Marta Facchinetti, Norberto Ariel Gandini, María Julia Ferronato, Julián Arévalo, Eliana Noelia Alonso, María Emilia Villegas, Alejandro López Romero, Diego Javier Obiol, María Eugenia Fermento, Alejandro Carlos Curino
Publikováno v:
Nutrition and cancer. 69(1)
D-Fraction is protein-bound β-1,6 and β-1,3 glucans (proteoglucan) extracted from the edible and medicinal mushroom Grifola frondosa (Maitake). The antitumoral effect of D-Fraction has long been exclusively attributed to their immunostimulatory cap
Autor:
Débora Gisele Salomón, Evangelina Mascaró, María Eugenia Fermento, Alejandro Carlos Curino, María Julia Ferronato, Cristian Vitale, Norberto Ariel Gandini, Maria Marta Facchinetti, Eliana Noelia Alonso, Yagamare Fall, Ana Rosa Raimondi, Diego Javier Obiol
The active form of vitamin D3, calcitriol, plays a major role in maintaining calcium/phosphate homeostasis. In addition, it is a potent antiproliferative and prodifferentiating agent. However, when effective antitumor doses of calcitriol are employed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79de57c8e660be0211110690df43baa4
Autor:
Norberto Ariel Gandini, María Eugenia Fermento, Jean C. Zenklusen, Julián Arévalo, Débora Gisele Salomón, Jorge Alejandro Blasco, Alejandro López Romero, Maria Marta Facchinetti, Alejandro Carlos Curino, Diego Javier Obiol, Nancy Carolina Andrés
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
In human glioma tumors, heme oxygenase-1 (HO-1) has been shown to be upregulated both when compared with normal brain tissues and also during oligodendroglioma progression. The cell types that express HO-1 have been shown to be mainly macrophages/mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c978e31ef359a454859b99a701a5c3f5
http://link.springer.com/article/10.1007/s13277-013-1373-z
http://link.springer.com/article/10.1007/s13277-013-1373-z
Autor:
Eliana Noelia Alonso, Manuela Meireles, Diego Javier Obiol, Ana Rocha, Gabriela A. Balogh, Gisela Joos, Raquel Soares, Ana Pirraco
For many years mushrooms have been used empirically in traditional medicine to treat several diseases. Study of the maitake mushroom, with its immunomodulatory and antitumoral properties, has led to the isolation of several bioactive compounds. One o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f376e1a9f631acc7c1805c34b08c62f2
https://www.liebertpub.com/doi/10.1089/jmf.2010.0095
https://www.liebertpub.com/doi/10.1089/jmf.2010.0095
Publikováno v:
Cancer Prevention Research. 5:B41-B41
Nutrigenomics is the scientific discipline that explains how nutrition can influence the switching on and off of genes and improve health outcomes. Is already known that eating healthy food helps our bodies get the needed nutrients for strengthening
Autor:
Ana Rocha, Manuela Meireles, Diego Javier Obiol, Eliana Noelia Alonso, Ana Pirraco, Raquel Soares, Gabriela A. Balogh
Publikováno v:
Cancer Research. 70:3570-3570
Background: Maitake mushroom has various bioactive compounds. D-fraction, a protein-bound polysaccharide compound, seems to be the most potent for enhancing the immune system via oral administration or injection. In previous studies, the combination