Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Diego H Castrillon"'
Publikováno v:
PLoS Genetics, Vol 12, Iss 8, p e1006215 (2016)
In mammals, females are born with finite numbers of oocytes stockpiled as primordial follicles. Oocytes are "reawakened" via an ovarian-intrinsic process that initiates their growth. The forkhead transcription factor Foxo3 controls reawakening downst
Externí odkaz:
https://doaj.org/article/e6a918fe0a614e4297645e4bf27d821b
Autor:
Yuji Nakada, Thomas G Stewart, Christopher G Peña, Song Zhang, Ni Zhao, Nabeel Bardeesy, Norman E Sharpless, Kwok-Kin Wong, D Neil Hayes, Diego H Castrillon
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73449 (2013)
Germline mutations in the LKB1 gene (also known as STK11) cause the Peutz-Jeghers Syndrome, and somatic loss of LKB1 has emerged as causal event in a wide range of human malignancies, including melanoma, lung cancer, and cervical cancer. The LKB1 pro
Externí odkaz:
https://doaj.org/article/6a00581d51954764bdb5a069e774041d
Autor:
Shana N Wingo, Teresa D Gallardo, Esra A Akbay, Mei-Chi Liang, Cristina M Contreras, Todd Boren, Takeshi Shimamura, David S Miller, Norman E Sharpless, Nabeel Bardeesy, David J Kwiatkowski, John O Schorge, Kwok-Kin Wong, Diego H Castrillon
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5137 (2009)
Human Papilloma Virus (HPV) is the etiologic agent for cervical cancer. Yet, infection with HPV is not sufficient to cause cervical cancer, because most infected women develop transient epithelial dysplasias that spontaneously regress. Progression to
Externí odkaz:
https://doaj.org/article/3059286e43eb4c01abf072239c4dba0e
This book presents new insights into the etiology and pathogenesis of systemic diseases recently discovered to be due to specific defects in molecular assemblies, organelles, or other subcellular structures. This new information, of great importance
Autor:
Subhransu S. Sahoo, Susmita G. Ramanand, Yunpeng Gao, Ahmed Abbas, Ashwani Kumar, Ileana C. Cuevas, Hao-Dong Li, Mitzi Aguilar, Chao Xing, Ram S. Mani, Diego H. Castrillon
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 12 (2022)
FOXA2 encodes a transcription factor mutated in 10% of endometrial cancers (ECs), with a higher mutation rate in aggressive variants. FOXA2 has essential roles in embryonic and uterine development. However, FOXA2’s role in EC is incompletely unders
Externí odkaz:
https://doaj.org/article/cf8174522e274db084cd063e8d4c544e
Autor:
Mitzi Aguilar, Hao Chen, Subhransu S. Sahoo, Wenxin Zheng, Jessica Grubman, Jeffrey A. SoRelle, Elena Lucas, Diego H. Castrillon
Publikováno v:
American Journal of Surgical Pathology. 47:618-629
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::357fb0c8fe3ed493faeea34a69f99f5d
https://doi.org/10.1097/pas.0000000000002034
https://doi.org/10.1097/pas.0000000000002034
Autor:
Rolf A. Brekken, Ke Ding, Xiaomei Ren, Diego H. Castrillon, Jason B. Fleming, Huamin Wang, Tae Hyun Hwang, Stefan Hinz, Zhen Wang, Moriah M. Hagopian, Wenting Du, Huocong Huang, Kristina Y. Aguilera
Supplementary Figure 1: 7rh reduces collagen-mediated signaling in a concentration-dependent manner in vivo; Supplementary Figure 2: 7rh inhibits Ddr1 activation in Pan02 tumors; Supplementary Figure 3: Inhibition of Ddr1 with 7rh does not induce obs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65e507d5d902b1df65cddbef5e96636f
https://doi.org/10.1158/1535-7163.22508715.v1
https://doi.org/10.1158/1535-7163.22508715.v1
Autor:
Rolf A. Brekken, Diego H. Castrillon, Michael T. Dellinger, Courtney D. Goldstein, Jason E. Toombs, Juliet G. Carbon, Hoon Hur, Lee B. Rivera, Kristina Y. Aguilera
PDF file - 2694K, Supplementary Figure 1: Characterization of tumor growth in KIC mice (LSL-KrasG12D; Cdkn2alox/lox; p48Cre). Supplementary Figure 2: Liver metastatic burden in KIC mice. Supplementary Figure 3: Level of hypoxia, collagen I, Hif1alpha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d633f130305ae541b61622be23e61b13
https://doi.org/10.1158/0008-5472.22402632
https://doi.org/10.1158/0008-5472.22402632
Autor:
Rolf A. Brekken, Diego H. Castrillon, Agnieszka Witkiewicz, Huamin Wang, Hiromi Yanagisawa, David A. Boothman, Zachary R. Moore, Christopher M. Wright, Jason E. Toombs, Mary Topalovski, Miao Wang
Fbln5 and α5β1 integrin expression pattern in mouse and human (S1); Characterization of KIC and KPC mice (S2); Examination of ROS levels in normal pancreas and NAC-treated KIC and RGE KIC tumors (S3); Reduced microvessel density (MVD) in RGE KIC an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67f02f365b30df5db83e68422d13141e
https://doi.org/10.1158/0008-5472.22406943
https://doi.org/10.1158/0008-5472.22406943
Autor:
Rolf A. Brekken, Diego H. Castrillon, Agnieszka Witkiewicz, Huamin Wang, Hiromi Yanagisawa, David A. Boothman, Zachary R. Moore, Christopher M. Wright, Jason E. Toombs, Mary Topalovski, Miao Wang
Description of additional methods and procedures used in the study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d3af3234c18bccf49f1c68cfadf6c90
https://doi.org/10.1158/0008-5472.22406940
https://doi.org/10.1158/0008-5472.22406940