Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Diego F. Coutinho"'
Autor:
Diego F. Coutinho, Mariana Boroni, Anna Beatriz W. Batalha, Danielle T. Vianna, Mayara Kalonji, Ana Paula S. Bueno, Soraia Rouxinol, Teresa S. Fernandez, Fabiana V. de Mello, Elaine S. Costa, Eliana Abdelhay, Bárbara C.R. Monte-Mór, Ilana R. Zalcberg
Publikováno v:
Pediatric Hematology Oncology Journal, Vol 6, Iss 3, Pp 123-126 (2021)
Despite all knowledge acquired regarding the mutational profile of pediatric myelodysplastic syndrome (MDS), the somatic genomic landscape underlying that disease remains unclear. We evaluated the presence of somatic variants in 37 genes related to m
Externí odkaz:
https://doaj.org/article/26ef857096634d93b5bb7562ffad77a2
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 7, Iss 6, Pp n/a-n/a (2019)
Externí odkaz:
https://doaj.org/article/23bc1bd948b948f184e2a9e0cf25d75c
Autor:
Jackline P. Ayres-Silva, Martin H. Bonamino, Maria E. Gouveia, Barbara C. R. Monte-Mor, Diego F. Coutinho, Adelmo H. Daumas, Cristiana Solza, Esteban Braggio, Ilana Renault Zalcberg
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
The genetic events associated with transformation of myeloproliferative neoplasms (MPNs) to secondary acute myeloid leukemia (sAML), particularly in the subgroup of essential thrombocythemia (ET) patients, remain incompletely understood. Deep studies
Externí odkaz:
https://doaj.org/article/4d51b80a03174b4cba55ca49aee3e7e0
Supplementary Figure 1 from Comprehensive Molecular Profiling of Desmoplastic Small Round Cell Tumor
Autor:
Neerav Shukla, Marc Ladanyi, Ahmet Zehir, Elli Papaemmanuil, Andrew L. Kung, Paul A. Meyers, Leonard H. Wexler, Michael P. LaQuaglia, Todd E. Heaton, Justin T. Gerstle, Gunes Gundem, Daoqi You, Nancy Bouvier, Katherine A. Thornton, Mrinal M. Gounder, William D. Tap, Shakeel Modak, Nestor Rosales, Glorymar I. Sanchez, Diego F. Coutinho, Filemon Dela Cruz, Max F. Levine, Anita S. Bowman, Emily K. Slotkin
Supplementary Figure 1 depicts copy number alterations in the described cohort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8092c0a779e8af5f72ce9dfe30cdf632
https://doi.org/10.1158/1541-7786.22525995.v1
https://doi.org/10.1158/1541-7786.22525995.v1
Autor:
Neerav Shukla, Marc Ladanyi, Ahmet Zehir, Elli Papaemmanuil, Andrew L. Kung, Paul A. Meyers, Leonard H. Wexler, Michael P. LaQuaglia, Todd E. Heaton, Justin T. Gerstle, Gunes Gundem, Daoqi You, Nancy Bouvier, Katherine A. Thornton, Mrinal M. Gounder, William D. Tap, Shakeel Modak, Nestor Rosales, Glorymar I. Sanchez, Diego F. Coutinho, Filemon Dela Cruz, Max F. Levine, Anita S. Bowman, Emily K. Slotkin
Supplementary Table 1 shows point mutations found in DSRCT samples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18101e727b13883957a6aa77461d9c6b
https://doi.org/10.1158/1541-7786.22525983
https://doi.org/10.1158/1541-7786.22525983
Supplementary Figure 3 from Comprehensive Molecular Profiling of Desmoplastic Small Round Cell Tumor
Autor:
Neerav Shukla, Marc Ladanyi, Ahmet Zehir, Elli Papaemmanuil, Andrew L. Kung, Paul A. Meyers, Leonard H. Wexler, Michael P. LaQuaglia, Todd E. Heaton, Justin T. Gerstle, Gunes Gundem, Daoqi You, Nancy Bouvier, Katherine A. Thornton, Mrinal M. Gounder, William D. Tap, Shakeel Modak, Nestor Rosales, Glorymar I. Sanchez, Diego F. Coutinho, Filemon Dela Cruz, Max F. Levine, Anita S. Bowman, Emily K. Slotkin
Supplementary Figure 3 provides a breakdown of the structural variant types found via whole genome sequencing in DSRCT samples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::418c34cb259455575b8d45bb37c7fa9d
https://doi.org/10.1158/1541-7786.22525989
https://doi.org/10.1158/1541-7786.22525989
Supplementary Figure 2 from Comprehensive Molecular Profiling of Desmoplastic Small Round Cell Tumor
Autor:
Neerav Shukla, Marc Ladanyi, Ahmet Zehir, Elli Papaemmanuil, Andrew L. Kung, Paul A. Meyers, Leonard H. Wexler, Michael P. LaQuaglia, Todd E. Heaton, Justin T. Gerstle, Gunes Gundem, Daoqi You, Nancy Bouvier, Katherine A. Thornton, Mrinal M. Gounder, William D. Tap, Shakeel Modak, Nestor Rosales, Glorymar I. Sanchez, Diego F. Coutinho, Filemon Dela Cruz, Max F. Levine, Anita S. Bowman, Emily K. Slotkin
Supplementary Figure 2 depicts whole genome sequencing findings
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1235fa2aa5fe711e16466965bf6c8325
https://doi.org/10.1158/1541-7786.22525992.v1
https://doi.org/10.1158/1541-7786.22525992.v1
Autor:
Neerav Shukla, Marc Ladanyi, Ahmet Zehir, Elli Papaemmanuil, Andrew L. Kung, Paul A. Meyers, Leonard H. Wexler, Michael P. LaQuaglia, Todd E. Heaton, Justin T. Gerstle, Gunes Gundem, Daoqi You, Nancy Bouvier, Katherine A. Thornton, Mrinal M. Gounder, William D. Tap, Shakeel Modak, Nestor Rosales, Glorymar I. Sanchez, Diego F. Coutinho, Filemon Dela Cruz, Max F. Levine, Anita S. Bowman, Emily K. Slotkin
Desmoplastic small round cell tumor (DSRCT) is characterized by the EWSR1–WT1 t(11;22) (p13:q12) translocation. Few additional putative drivers have been identified, and research has suffered from a lack of model systems. Next-generation sequencing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02fa64311b402d6284950caa23f130cd
https://doi.org/10.1158/1541-7786.c.6544977.v1
https://doi.org/10.1158/1541-7786.c.6544977.v1
Supplementary Figure 4 from Comprehensive Molecular Profiling of Desmoplastic Small Round Cell Tumor
Autor:
Neerav Shukla, Marc Ladanyi, Ahmet Zehir, Elli Papaemmanuil, Andrew L. Kung, Paul A. Meyers, Leonard H. Wexler, Michael P. LaQuaglia, Todd E. Heaton, Justin T. Gerstle, Gunes Gundem, Daoqi You, Nancy Bouvier, Katherine A. Thornton, Mrinal M. Gounder, William D. Tap, Shakeel Modak, Nestor Rosales, Glorymar I. Sanchez, Diego F. Coutinho, Filemon Dela Cruz, Max F. Levine, Anita S. Bowman, Emily K. Slotkin
Supplementary Figure 4 shows data related to FGFR4 inhibition in DSRCT and control models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eef8ee28d713025b77b915a43ad85d1
https://doi.org/10.1158/1541-7786.22525986.v1
https://doi.org/10.1158/1541-7786.22525986.v1
Autor:
Neerav Shukla, Marc Ladanyi, Ahmet Zehir, Elli Papaemmanuil, Andrew L. Kung, Paul A. Meyers, Leonard H. Wexler, Michael P. LaQuaglia, Todd E. Heaton, Justin T. Gerstle, Gunes Gundem, Daoqi You, Nancy Bouvier, Katherine A. Thornton, Mrinal M. Gounder, William D. Tap, Shakeel Modak, Nestor Rosales, Glorymar I. Sanchez, Diego F. Coutinho, Filemon Dela Cruz, Max F. Levine, Anita S. Bowman, Emily K. Slotkin
Supplementary Table 2 shows the raw data further described in Figure 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::512a7b67c36a185ca631d4d05ad203d8
https://doi.org/10.1158/1541-7786.22525980.v1
https://doi.org/10.1158/1541-7786.22525980.v1