Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Diego Enry, Barreto Gomes"'
Autor:
Lilian Hernández Alvarez, Diego Enry Barreto Gomes, Jorge Enrique Hernández González, Pedro Geraldo Pascutti
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0211227 (2019)
Trypanosoma cruzi is the causative agent of Chagas disease, a neglected infection affecting millions of people in tropical regions. There are several chemotherapeutic agents for the treatment of this disease, but most of them are highly toxic and gen
Externí odkaz:
https://doaj.org/article/b249e55470ec4b2bb6860120a89b8e61
Publikováno v:
Journal of the American Chemical Society.
The unbinding pathway of a protein complex can vary significantly depending on biochemical and mechanical factors. Under mechanical stress, a complex may dissociate through a mechanism different from that used in simple thermal dissociation, leading
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d33bf8c9e59d55a1e358bcbca4b275f
https://pubmed.ncbi.nlm.nih.gov/36455202
https://pubmed.ncbi.nlm.nih.gov/36455202
Autor:
Rafael Bernardi, Marcelo Cardoso dos Reis Melo, Priscila Da Silva Figueiredo Celestino Gomes, Diego Enry Barreto Gomes
Staphylococci bacteria use an arsenal of virulence factors, mainly composed of proteins such as adhesins, to target and adhere to their host. Adhesins play critical roles during infection, mainly during the early steps of adhesion when cells are expo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ad74cefa4d8e92d791d54cfe3a2326f
https://doi.org/10.1101/2022.07.14.500151
https://doi.org/10.1101/2022.07.14.500151
Mechanoactive proteins are essential for a myriad of physiological and pathological processes. Guided by the advances in single-molecule force spectroscopy (SMFS), we have reached a molecular-level understanding of how several mechanoactive proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::748bf1edf8292147f2b9db5dfabb3836
https://doi.org/10.1101/2022.06.30.498329
https://doi.org/10.1101/2022.06.30.498329
Neste trabalho, simulações de dinâmica molecular foram realizadas com as proteínas mutantes L81N, I88N, L81NI88N e L50S, a fim de entender o efeito dessas mutações na estrutura e estabilidade dessas proteínas. Os dímeros formados por proteín
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a5d05fb14eef106932c200648898769
https://doi.org/10.53268/bkf22050102
https://doi.org/10.53268/bkf22050102
Autor:
Lilian Hernández Alvarez, Dany Naranjo Feliciano, Jorge Enrique Hernández González, R O Soares, Diego Enry Barreto Gomes, Pedro Geraldo Pascutti
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 5, p e0003759 (2015)
BACKGROUND:Fasciola hepatica is the causative agent of fascioliasis, a disease affecting grazing animals, causing economic losses in global agriculture and currently being an important human zoonosis. Overuse of chemotherapeutics against fascioliasis
Externí odkaz:
https://doaj.org/article/a3fafc32fcbc40b29fbdb1dc4795c627
Autor:
Jorge Enrique, Hernández González, Emir, Salas-Sarduy, Lilian, Hernández Alvarez, Diego Enry, Barreto Gomes, Pedro Geraldo, Pascutti, Chris, Oostenbrink, Vitor B P, Leite
Publikováno v:
Journal of computer-aided molecular design. 35(10)
Falcipain-2 (FP-2) is a Plasmodium falciparum hemoglobinase widely targeted in the search for antimalarials. FP-2 can be allosterically modulated by various noncompetitive inhibitors that have been serendipitously identified. Moreover, the crystal st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::37126fde44d581c4dc16eb31a9924402
https://pubmed.ncbi.nlm.nih.gov/34617191
https://pubmed.ncbi.nlm.nih.gov/34617191
Autor:
Adrien Henri Cerdan, Marion Sisquellas, Diego Enry Barreto Gomes, Gilberto P Pereira, Jean-Pierre Changeux, Marco Cecchini
Publikováno v:
Bioinformatics
Bioinformatics, Oxford University Press (OUP), 2020, ⟨10.1093/bioinformatics/btaa170⟩
Bioinformatics, 2020, ⟨10.1093/bioinformatics/btaa170⟩
Bioinformatics, Oxford University Press (OUP), 2020, ⟨10.1093/bioinformatics/btaa170⟩
Bioinformatics, 2020, ⟨10.1093/bioinformatics/btaa170⟩
Motivation Glycine receptors (GlyRs) mediate fast inhibitory neurotransmission in the brain and have been recognized as key pharmacological targets for pain. A large number of chemically diverse compounds that are able to modulate GlyR function both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d739123912cfa0866f9c75ffd8f1613
https://hal.archives-ouvertes.fr/hal-02511258/document
https://hal.archives-ouvertes.fr/hal-02511258/document
Autor:
Igor P. V. Vieira, Diego Enry Barreto Gomes, Rafael D. Mesquita, Leonardo de Figueiredo Vilela, Gabrielle T. Cordeiro, Elis C. A. Eleutherio, Bianca Cruz Neves, Rafael D. Melani, Gilberto B. Domont
Publikováno v:
AMB Express
AMB Express, Vol 9, Iss 1, Pp 1-12 (2019)
AMB Express, Vol 9, Iss 1, Pp 1-12 (2019)
The inability of the yeast Saccharomyces cerevisiae to produce ethanol from xylose has hampered the biofuel production from lignocellulosic biomass. However, prior studies reveal that functional expression of xylose isomerase (XI) from Burkholderia c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc3e2e5f40cf3d26487b74ca54b0b4be
https://pubmed.ncbi.nlm.nih.gov/31127459
https://pubmed.ncbi.nlm.nih.gov/31127459
Autor:
Lilian Hernández Alvarez, Diego Enry Barreto Gomes, Pedro Geraldo Pascutti, Jorge Enrique Hernández González
Publikováno v:
PLoS ONE
Web of Science
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
PLoS ONE, Vol 14, Iss 1, p e0211227 (2019)
Web of Science
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
PLoS ONE, Vol 14, Iss 1, p e0211227 (2019)
Made available in DSpace on 2019-10-04T12:34:52Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-01-25 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Try
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eadf40d2180953b3c950b684edbbcd63
https://pubmed.ncbi.nlm.nih.gov/30682119
https://pubmed.ncbi.nlm.nih.gov/30682119