Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Diego A. Lema"'
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
IntroductionCardiac presentation of autoimmune sarcoidosis, known as cardiac sarcoidosis (CS), is a poorly understood disease with high mortality and low diagnosis rate. While CS is an immunological syndrome, little is known about how cardiac parench
Externí odkaz:
https://doaj.org/article/ee04ce3e59324f34ad8da70aec096fa2
Donor HLA−DR Drives the Development of De Novo Autoimmunity Following Lung and Heart Transplantation
Autor:
Ewa Jankowska−Gan, MS, Vrushali V. Agashe, PhD, Diego A. Lema, MD, Ying Zhou, MS, Laura Gonzalez Bosc, PhD, Jeremy A. Sullivan, PhD, Daniel S. Greenspan, PhD, William J. Burlingham, PhD
Publikováno v:
Transplantation Direct, Vol 6, Iss 10, p e607 (2020)
Background. Individuals harbor preexisting HLA−DR/DQ−restricted responses to collagen type V (ColV) mediated by Th17 cells under Treg control, both specific to peptides that bind to inherited HLA class II antigens. Yet after transplant, the donor
Externí odkaz:
https://doaj.org/article/440bd605fad843e1bb8e3d2b1e36fbab
Autor:
Jeremy A. Sullivan, Yusuke Tomita, Ewa Jankowska-Gan, Diego A. Lema, Matt P. Arvedson, Ashita Nair, William Bracamonte-Baran, Ying Zhou, Kristy K. Meyer, Weixiong Zhong, Deepali V. Sawant, Andrea L. Szymczak-Workman, Qianxia Zhang, Creg J. Workman, Seungpyo Hong, Dario A.A. Vignali, William J. Burlingham
Publikováno v:
Cell Reports, Vol 30, Iss 4, Pp 1039-1051.e5 (2020)
Summary: Interleukin-35 (IL-35) is an immunosuppressive cytokine composed of Epstein-Barr-virus-induced protein 3 (Ebi3) and IL-12α chain (p35) subunits, yet the forms that IL-35 assume and its role in peripheral tolerance remain elusive. We induce
Externí odkaz:
https://doaj.org/article/19bc2a5483074d60bb874b0ead25e86d
Publikováno v:
ACTAS DEL VII CONGRESO INVESTIGACIÓN, DESARROLLO E INNOVACIÓN DE LA UNIVERSIDAD INTERNACIONAL DE CIENCIA Y TECNOLOGÍA IDI-UNICyT 2022.
Introducción: en la actualidad debido a distintos factores socio económicos resulta imperativo llevar a cabo procesos tecnológicos eficientes y que den como resultado productos de alta calidad y posicionamiento en el medio. Se planteó llevar a ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9804f1b18943d343557bd05ff9b38510
https://doi.org/10.47300/actasidi-unicyt-2022-03
https://doi.org/10.47300/actasidi-unicyt-2022-03
Publikováno v:
Circulation Research. 131
IL-1, IL-33 and IL-36 have complementary, pro-inflammatory roles during the immune response that promote autoimmune diseases, particularly myocarditis. While antibodies that neutralize circulating cytokines exist, we hypothesized that blockade of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0079346453f53ddd61fd0a7fb5406333
https://doi.org/10.1161/res.131.suppl_1.p3061
https://doi.org/10.1161/res.131.suppl_1.p3061
Autor:
Diego A. Lema, Ewa Jankowska-Gan, Ashita Nair, Sami B. Kanaan, Christopher J. Little, David P. Foley, Afsar Raza Naqvi, Jianxin Wang, Seungpyo Hong, J. Lee Nelson, David Al-Adra, William J. Burlingham, Jeremy A. Sullivan
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 22(5)
Exposure to non-inherited maternal antigens (NIMA) during the fetal period induces lifelong split tolerance to grafts expressing these allo-antigens. In adult mice, the production of extracellular vesicles (EVs) from maternal microchimeric cells caus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65073b17ef81b499727af95114a73a0d
https://pubmed.ncbi.nlm.nih.gov/35143105
https://pubmed.ncbi.nlm.nih.gov/35143105
Donor HLA−DR Drives the Development of De Novo Autoimmunity Following Lung and Heart Transplantation
Autor:
Jeremy A. Sullivan, Diego A Lema, Laura V. Gonzalez Bosc, Ewa Jankowska Gan, Ying Zhou, Daniel S. Greenspan, Vrushali V. Agashe, William J. Burlingham
Publikováno v:
Transplantation Direct
Transplantation Direct, Vol 6, Iss 10, p e607 (2020)
Transplantation Direct, Vol 6, Iss 10, p e607 (2020)
Background. Individuals harbor preexisting HLA−DR/DQ−restricted responses to collagen type V (ColV) mediated by Th17 cells under Treg control, both specific to peptides that bind to inherited HLA class II antigens. Yet after transplant, the donor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66de25560477f0d999bc9b18a8520861
http://europepmc.org/articles/PMC7515617
http://europepmc.org/articles/PMC7515617
Autor:
Diego A Lema, William J. Burlingham
Publikováno v:
Scandinavian Journal of Immunology. 90
Exosomes are a potent means for intercellular communication. However, exosomes have received intensive research focus in immunobiology only relatively recently. Because they transport proteins, lipids and genetic material between cells, they are espe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7abb7d7ba308b05c44a3203d3b9daa6b
https://doi.org/10.1111/sji.12807
https://doi.org/10.1111/sji.12807
Publikováno v:
Journal for Immunotherapy of Cancer
ObjectivesEmerging evidence has shown a role for tumor antigen-specific regulation in cancer. Identifying individuals with pre-existing regulatory responses may be key to understand those who are more likely to respond to Programmed Death-1 (PD-1) or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bae01b184216e1d05548ff87c1a7a81
https://doi.org/10.1136/jitc-2019-000152
https://doi.org/10.1136/jitc-2019-000152
Autor:
Yusuke Tomita, William J. Burlingham, Dario A. A. Vignali, Ying Zhou, Jeremy A. Sullivan, Diego A Lema
Publikováno v:
Transplantation. 102:S328-S329
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f74a62c683513ed427461937ed0b45d6
https://doi.org/10.1097/01.tp.0000543057.28120.c8
https://doi.org/10.1097/01.tp.0000543057.28120.c8