Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Diego, Tesauro"'
Autor:
Maria Marzano, Filippo Prencipe, Pietro Delre, Giuseppe Felice Mangiatordi, Gabriele Travagliante, Luisa Ronga, Gennaro Piccialli, Michele Saviano, Stefano D’Errico, Diego Tesauro, Giorgia Oliviero
Publikováno v:
Molecules, Vol 29, Iss 22, p 5446 (2024)
Herein, we report the structure-based selection via molecular docking of four N-heterocyclic bis-carbene gold(I) complexes, whose potential as ligands for the hTel23 G-quadruplex structure has been investigated using circular dichroism (CD) spectrosc
Externí odkaz:
https://doaj.org/article/fa4d5e2d3e204837a0e815615d35e6d0
Autor:
Vincenza De Gregorio, Alessandra La Pietra, Andrea Candela, Carlo Oliviero, Ida Ferrandino, Diego Tesauro
Publikováno v:
Current Research in Toxicology, Vol 6, Iss , Pp 100174- (2024)
Gold complexes can be a useful system in the fight against cancer. Although many studies have been carried out on in vitro 2D cell culture models embryotoxic assays are particularly lacking. Embryotoxicity and DNA damage are critical concerns in drug
Externí odkaz:
https://doaj.org/article/1dda750de81b4c76878c74082d578715
Publikováno v:
Molecules, Vol 28, Iss 11, p 4435 (2023)
Silver has a long history of antimicrobial activity and received an increasing interest in last decades owing to the rise in antimicrobial resistance. The major drawback is the limited duration of its antimicrobial activity. The broad-spectrum silver
Externí odkaz:
https://doaj.org/article/f919c9feef314d81903a0157df723a61
Autor:
Giuseppa Augello, Antonina Azzolina, Filomena Rossi, Filippo Prencipe, Giuseppe Felice Mangiatordi, Michele Saviano, Luisa Ronga, Melchiorre Cervello, Diego Tesauro
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 466 (2023)
Among the non-platinum antitumor agents, gold complexes have received increased attention owing to their strong antiproliferative effects, which generally occur through non-cisplatin-like mechanisms of action. Several studies have revealed that many
Externí odkaz:
https://doaj.org/article/510bbe6e65004d9db12b28e49b680f15
Publikováno v:
Molecules, Vol 26, Iss 13, p 4049 (2021)
Precision medicine is based on innovative administration methods of active principles. Drug delivery on tissue of interest allows improving the therapeutic index and reducing the side effects. Active targeting by means of drug-encapsulated micelles d
Externí odkaz:
https://doaj.org/article/5d88344a0ff941208e845db3091fc60e
Autor:
Diego Tesauro, Mikel Bernabeu De Maria, Giovanni Chiappetta, Michele Saviano, Ryszard Lobinski, Luisa Ronga
Thioredoxin (Trx) and Thioredoxin Reductase (TrxR) enzymes are essential constituents of the Trx system involved in the cellular redox regulation network. This mitochondrial apparatus, in recent years, has been recognized as an important modulator of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3730::61438694e5cee18e471da46fbf42d61d
https://hdl.handle.net/11588/908513
https://hdl.handle.net/11588/908513
Autor:
Diego Tesauro, Mikel Bernabeu De Maria, Christine Enjalbal, Filomena Rossi, Michele Saviano, Ryszard Lobinski, Luisa Ronga
Selenium (Se) is an essential element being present in the form of the naturally occurring amino acid selenocysteine (Sec), 25 human proteins involved in different cellular pathways contain Sec. As the most potent intracellular soft Lewis base, selen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3730::806e2678d6be3e89ce8acb7e49621831
https://hdl.handle.net/11588/908516
https://hdl.handle.net/11588/908516
Autor:
Diego Tesauro, Antonella Accardo, Carlo Diaferia, Vittoria Milano, Jean Guillon, Luisa Ronga, Filomena Rossi
Publikováno v:
Molecules, Vol 24, Iss 2, p 351 (2019)
Peptides of natural and synthetic sources are compounds operating in a wide range of biological interactions. They play a key role in biotechnological applications as both therapeutic and diagnostic tools. They are easily synthesized thanks to solid-
Externí odkaz:
https://doaj.org/article/5d8ad895a6d7402782dc60c6ccd6b245
Autor:
Diego Tesauro
The use of metal complexes for health and healing has been in use for over the last several millennia and perhaps longer [...]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8f16df93a0f556cbdad6121ed919b4b
https://hdl.handle.net/11588/908511
https://hdl.handle.net/11588/908511
Publikováno v:
Molecules
Molecules, Vol 26, Iss 4049, p 4049 (2021)
Molecules, Vol 26, Iss 4049, p 4049 (2021)
Precision medicine is based on innovative administration methods of active principles. Drug delivery on tissue of interest allows improving the therapeutic index and reducing the side effects. Active targeting by means of drug-encapsulated micelles d