Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Diego, Kauffmann-Guerrero"'
Autor:
Laura Lambrecht, Paola Arnold, Jürgen Behr, Pontus Mertsch, Amanda Tufman, Diego Kauffmann-Guerrero
Publikováno v:
Diagnostics, Vol 14, Iss 14, p 1572 (2024)
Background: Small-cell lung cancer (SCLC) is a highly aggressive tumor, and overall survival (OS) remains poor despite intensive efforts to develop new treatment strategies. In second line, topotecan is the only approved drug, with a median OS of 5.9
Externí odkaz:
https://doaj.org/article/89c9e67cc73c478981ce47b07e8ccdaa
Autor:
Lukas Wehlte, Julia Walter, Lea Daisenberger, Felix Kuhnle, Maria Ingenerf, Christine Schmid-Tannwald, Matthias Brendel, Diego Kauffmann-Guerrero, Lucie Heinzerling, Amanda Tufman, Thomas Pfluger, Friederike Völter
Publikováno v:
Diagnostics, Vol 14, Iss 11, p 1139 (2024)
Background: A debate persists on the prognostic value of the pre-therapeutic standardized uptake value (SUV) of non-tumorous lung tissue for the risk assessment of therapy-related pneumonitis, with most studies lacking significant correlation. Howeve
Externí odkaz:
https://doaj.org/article/b5762d8df97f407c91d6c5083b1b3595
Autor:
Oliver Illini, Felix Carl Saalfeld, Petros Christopoulos, Michaël Duruisseaux, Anders Vikström, Nir Peled, Ingel Demedts, Elizabeth Dudnik, Anna Eisert, Sayed M. S. Hashemi, Urska Janzic, Waleed Kian, Katja Mohorcic, Saara Mohammed, Maria Silvoniemi, Sacha I. Rothschild, Christian Schulz, Claas Wesseler, Alfredo Addeo, Karin Armster, Malinda Itchins, Marija Ivanović, Diego Kauffmann-Guerrero, Jussi Koivunen, Jonas Kuon, Nick Pavlakis, Berber Piet, Martin Sebastian, Janna-Lisa Velthaus-Rusik, Luciano Wannesson, Marcel Wiesweg, Robert Wurm, Corinna Albers-Leischner, Daniela E. Aust, Melanie Janning, Hannah Fabikan, Sylvia Herold, Anna Klimova, Sonja Loges, Yana Sharapova, Maret Schütz, Christoph Weinlinger, Arschang Valipour, Tobias Raphael Overbeck, Frank Griesinger, Marko Jakopovic, Maximilian J. Hochmair, Martin Wermke
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 3992 (2024)
EGFR exon 20 (EGFR Ex20) insertion mutations in non-small cell lung cancer (NSCLC) are insensitive to traditional EGFR tyrosine kinase inhibitors (TKIs). Mobocertinib is the only approved TKI specifically designed to target EGFR Ex20. We performed an
Externí odkaz:
https://doaj.org/article/6ed7bccf8a6a4049820a8177574fd8c6
Autor:
Julia Walter, Diego Kauffmann‐Guerrero, Thomas Muley, Martin Reck, Jan Fuge, Andreas Günther, Raphael W. Majeed, Rajkumar Savai, Ina Koch, Julien Dinkel, Christian Schneider, Karsten Senghas, Sonja Kobinger, Farkhad Manapov, Michael Thomas, Kathrin Kahnert, Hauke Winter, Jürgen Behr, Martin Tammemägi, Amanda Tufman
Publikováno v:
Cancer Medicine, Vol 12, Iss 7, Pp 8880-8896 (2023)
Abstract Introduction Trials of CT‐based screening for lung cancer have shown a mortality advantage for screening in North America and Europe. Before introducing a nationwide lung cancer screening program in Germany, it is important to assess the c
Externí odkaz:
https://doaj.org/article/4671f4b7e0c547e688273a2e674df6ca
Autor:
Kathrin Kahnert, Lilli Maria Lempert, Jürgen Behr, Laura Elsner, Toki Bolt, Amanda Tufman, Diego Kauffmann-Guerrero
Publikováno v:
Therapeutic Advances in Respiratory Disease, Vol 17 (2023)
Background: Small cell lung cancer (SCLC) is characterized by aggressive growth and poor prognosis. Although SCLC affects nearly exclusively heavy smokers and leads to frequent respiratory symptoms, the impact of pre-therapeutic lung function testing
Externí odkaz:
https://doaj.org/article/63aff9d19eec4b0d81b53fc14f232357
Autor:
Kathrin Kahnert, Rudolf A. Jörres, Hans-Ulrich Kauczor, Peter Alter, Franziska C. Trudzinski, Felix Herth, Bertram Jobst, Oliver Weinheimer, Sebastian Nauck, Pontus Mertsch, Diego Kauffmann-Guerrero, Jürgen Behr, Robert Bals, Henrik Watz, Klaus F. Rabe, Tobias Welte, Claus F. Vogelmeier, Jürgen Biederer
Publikováno v:
Therapeutic Advances in Respiratory Disease, Vol 17 (2023)
Background: Chest computed tomography (CT) is increasingly used for phenotyping and monitoring of patients with COPD. The aim of this work was to evaluate the association of Pi10 as a measure of standardized airway wall thickness on CT with exacerbat
Externí odkaz:
https://doaj.org/article/5479cd8ba73d44879fe4dc190922a94a
Autor:
Julia Walter, Laura Sellmer, Kathrin Kahnert, Rosemarie Kiefl, Zulfiya Syunyaeva, Diego Kauffmann-Guerrero, Farkhad Manapov, Christian Schneider, Juergen Behr, Amanda Tufman
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-10 (2022)
Abstract Background The novel coronavirus SARS-CoV-2 has caused a global COVID-19 pandemic, leading to worldwide changes in public health measures. In addition to changes in the public sector (lockdowns, contact restrictions), hospitals modified care
Externí odkaz:
https://doaj.org/article/63b78f9782894e0599323bb23d6c5519
Autor:
Christina Kellerer, Rudolf A. Jörres, Antonius Schneider, Peter Alter, Hans-Ulrich Kauczor, Bertram Jobst, Jürgen Biederer, Robert Bals, Henrik Watz, Jürgen Behr, Diego Kauffmann-Guerrero, Johanna Lutter, Alexander Hapfelmeier, Helgo Magnussen, Franziska C. Trudzinski, Tobias Welte, Claus F. Vogelmeier, Kathrin Kahnert
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-11 (2021)
Abstract Background Lung emphysema is an important phenotype of chronic obstructive pulmonary disease (COPD), and CT scanning is strongly recommended to establish the diagnosis. This study aimed to identify criteria by which physicians with limited t
Externí odkaz:
https://doaj.org/article/7abfe002a0824d03b457586791eb9846
Autor:
Toki Bolt, Amanda Tufman, Laura Sellmer, Kathrin Kahnert, Pontus Mertsch, Julia Kovács, Diego Kauffmann-Guerrero, Dieter Munker, Farkhad Manapov, Christian Schneider, Juergen Behr, Julia Walter
Publikováno v:
Clinical Medicine Insights: Oncology, Vol 16 (2022)
Background: The COVID-19 vaccines, face masks, and social distancing are effective interventions to prevent SARS-CoV-2 infections. In this study, we aimed to determine lung cancer patients’ attitudes toward vaccination, changes in behavior after va
Externí odkaz:
https://doaj.org/article/ac7308fb3cde41979d35b0dde3a6f9ad
Autor:
Diego Kauffmann-Guerrero, Kathrin Kahnert, Rosemarie Kiefl, Laura Sellmer, Julia Walter, Jürgen Behr, Amanda Tufman
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Treatment with single agent immune checkpoint inhibitors (ICIs) has tremendously changed second line therapy in NSCLC. However, there are still no reliable biomarkers predicting response and survival in this group of patients. PD-L1 revealed
Externí odkaz:
https://doaj.org/article/258b0d0ca095449cbb7b82735f688793