Zobrazeno 1 - 9
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pro vyhledávání: '"Diego, Duchi"'
Publikováno v:
Nucleic Acids Research
RNA polymerase (RNAP) contains a mobile structural module, the “clamp,” that forms one wall of the RNAP active-center cleft and that has been linked to crucial aspects of the transcription cycle, including loading of promoter DNA into the RNAP ac
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https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81f474b5599df47ff0de4f54b1ea5bb3
http://ora.ox.ac.uk/objects/uuid:
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Autor:
Yi Jiang, Kalyan Das, Diego Duchi, Aashish Srivastava, Achillefs N. Kapanidis, Dongye Wang, Stefano Donadio, Ruiheng Yin, Haibo Zhang, Edward T. Eng, Changsheng Zhang, Abhishek Mazumder, Elena V. Sineva, Yon W. Ebright, Richard Y. Ebright, Dennis Thomas, Sukhendu Mandal, Matthew Gigliotti, David Degen, Wei Lin, Yu Liu, Richard H. Ebright, Zhening Zhang
Fidaxomicin is an antibacterial drug in clinical use in treatment ofClostridium difficilediarrhea1–2. The active pharmaceutical ingredient of fidaxomicin, lipiarmycin A3 (Lpm)1–4, is a macrocyclic antibiotic with bactericidal activity against Gra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2553581500b230508ee39bba9f6b22e7
https://europepmc.org/articles/PMC6205224/
https://europepmc.org/articles/PMC6205224/
Autor:
Diego, Duchi, Kristofer, Gryte, Nicole C, Robb, Zakia, Morichaud, Carol, Sheppard, Konstantin, Brodolin, Sivaramesh, Wigneshweraraj, Achillefs N, Kapanidis
Publikováno v:
Nucleic Acids Research
Transcription initiation is a major step in gene regulation for all organisms. In bacteria, the promoter DNA is first recognized by RNA polymerase (RNAP) to yield an initial closed complex. This complex subsequently undergoes conformational changes r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b7ff63dee0f9d4027a71ee78510418f3
https://pubmed.ncbi.nlm.nih.gov/29177430
https://pubmed.ncbi.nlm.nih.gov/29177430
Publikováno v:
Biophysical Journal. 110(3)
We present recent work that applies smFRET techniques to the early stages of bacterial transcription in which DNA is transcribed into RNA, resulting in a FRET change as a DNA template is transcribed. The mechanism of initial transcription is unclear,
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https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fe10d2810e9e464c5243532e210ae3c
Autor:
Thorben Cordes, Richard H. Ebright, Nicole C. Robb, Yusdi Santoso, Achillefs N. Kapanidis, Timothy D. Craggs, Ling Chin Hwang, Kristofer Gryte, Diego Duchi, Shimon Weiss
Publikováno v:
Journal of Molecular Biology; Vol 425
Journal of Molecular Biology
Journal of Molecular Biology, 425(5), 875-885. Academic Press
Journal of Molecular Biology
Journal of Molecular Biology, 425(5), 875-885. Academic Press
Bacterial transcription is initiated after RNA polymerase (RNAP) binds to promoter DNA, melts similar to 14 bp around the transcription start site and forms a single-stranded "transcription bubble" within a catalytically active RNAP-DNA open complex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe969437efd5a453d7002943bb8215f8
https://pubmed.ncbi.nlm.nih.gov/23274143
https://pubmed.ncbi.nlm.nih.gov/23274143
Publikováno v:
BIOPHYSICAL JOURNAL. 102(3)
Transcription initiation is a highly regulated process whereby RNA polymerase (RNAP) binds to promoter DNA and undergoes numerous conformational changes which melt ∼14 base-pairs around the transcription start site and form the RNAP-DNA open comple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::538cd4194b14657c65850ac2410e35cf
http://ora.ox.ac.uk/objects/uuid:3a875a98-3f08-4322-8122-fcba289c8e05
http://ora.ox.ac.uk/objects/uuid:3a875a98-3f08-4322-8122-fcba289c8e05
Autor:
Anne Plochowietz, Tom Brown, Pawel Zawadzki, Achillefs N. Kapanidis, Afaf H. El-Sagheer, Diego Duchi Llumigusin
Publikováno v:
Biophysical Journal. 108:115a
Transcription initiation is the most important step in gene regulation and is orchestrated by RNA polymerase (RNAP). However, its molecular mechanisms have remained unclear due to the presence of transient intermediates and heterogeneity.To character
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81924c16e4d8e86d9133a07c4b5d96c1
https://doi.org/10.1016/j.bpj.2014.11.646
https://doi.org/10.1016/j.bpj.2014.11.646
Autor:
Plochowietz, Anne, Llumigusin, Diego Duchi, Zawadzki, Pawel, El-Sagheer, Afaf H., Brown, Tom, Kapanidis, Achillefs N.
Publikováno v:
In Biophysical Journal 27 January 2015 108(2) Supplement 1:115a-115a
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