Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Diego, Alignani"'
Autor:
Esperanza Martín-Sánchez, Luis-Esteban Tamariz-Amador, Camila Guerrero, Anastasiia Zherniakova, Aintzane Zabaleta, Catarina Maia, Laura Blanco, Diego Alignani, Maria-Antonia Fortuño, Carlos Grande, Andrea Manubens, Jose-Maria Arguiñano, Clara Gomez, Ernesto Perez-Persona, Iñigo Olazabal, Itziar Oiartzabal, Carlos Panizo, Felipe Prosper, Jesus F. San-Miguel, Paula Rodriguez-Otero, Bruno Paiva, the Asociación Vasco-Navarra de Hematología y Hemoterapia (ASOVASNA) cooperative group
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Infection is the leading cause of death in multiple myeloma (MM). However, the cellular composition associated with immune dysfunction is not defined. We analyzed immune profiles in the peripheral blood of patients with MM (n = 28) and B-cel
Externí odkaz:
https://doaj.org/article/d290946f1de348f38a26beba2fae6800
Autor:
Edurne San José-Enériz, Naroa Gimenez-Camino, Obdulia Rabal, Leire Garate, Estibaliz Miranda, Nahia Gómez-Echarte, Fernando García, Stella Charalampopoulou, Elena Sáez, Amaia Vilas-Zornoza, Patxi San Martín-Uriz, Luis V. Valcárcel, Naroa Barrena, Diego Alignani, Luis Esteban Tamariz-Amador, Ana Pérez-Ruiz, Sebastian Hilscher, Mike Schutkowski, Ana Alfonso-Pierola, Nicolás Martinez-Calle, María José Larrayoz, Bruno Paiva, María José Calasanz, Javier Muñoz, Marta Isasa, José Ignacio Martin-Subero, Antonio Pineda-Lucena, Julen Oyarzabal, Xabier Agirre, Felipe Prósper
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract Despite the development of novel therapies for acute myeloid leukemia, outcomes remain poor for most patients, and therapeutic improvements are an urgent unmet need. Although treatment regimens promoting differentiation have succeeded in the
Externí odkaz:
https://doaj.org/article/c19f4277205c445384d53303bce19ff2
Autor:
Nerea Berastegui, Marina Ainciburu, Juan P. Romero, Paula Garcia-Olloqui, Ana Alfonso-Pierola, Céline Philippe, Amaia Vilas-Zornoza, Patxi San Martin-Uriz, Raquel Ruiz-Hernández, Ander Abarrategi, Raquel Ordoñez, Diego Alignani, Sarai Sarvide, Laura Castro-Labrador, José M. Lamo-Espinosa, Mikel San-Julian, Tamara Jimenez, Félix López-Cadenas, Sandra Muntion, Fermin Sanchez-Guijo, Antonieta Molero, Maria Julia Montoro, Bárbara Tazón, Guillermo Serrano, Aintzane Diaz-Mazkiaran, Mikel Hernaez, Sofía Huerga, Findlay Bewicke-Copley, Ana Rio-Machin, Matthew T. Maurano, María Díez-Campelo, David Valcarcel, Kevin Rouault-Pierre, David Lara-Astiaso, Teresa Ezponda, Felipe Prosper
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Myelodysplastic syndromes (MDS) are age-related pathologies in which alterations of hematopoietic stem cells lead to abnormal formation of blood cells. Here, the authors study the lesions that these cells undergo in aging and disease, characterizing
Externí odkaz:
https://doaj.org/article/5a52f5ed769d4553afa3673e2f1e7052
Autor:
Miren Lasaga, Paula Río, Amaia Vilas-Zornoza, Nuria Planell, Susana Navarro, Diego Alignani, Beatriz Fernández-Varas, Daniel Mouzo, Josune Zubicaray, Roser M. Pujol, Eileen Nicoletti, Jonathan D. Schwartz, Julián Sevilla, Marina Ainciburi, Asier Ullate-Agote, Jordi Surrallés, Rosario Perona, Leandro Sastre, Felipe Prosper, David Gomez-Cabrero, Juan A. Bueren
Publikováno v:
Haematologica, Vol 108, Iss 10 (2023)
Clinical trials have shown that lentiviral-mediated gene therapy can ameliorate bone marrow failure (BMF) in nonconditioned Fanconi anemia (FA) patients resulting from the proliferative advantage of corrected FA hematopoietic stem and progenitor cell
Externí odkaz:
https://doaj.org/article/d53a95898f024aef96171022924acc08
Autor:
Marina Ainciburu, Teresa Ezponda, Nerea Berastegui, Ana Alfonso-Pierola, Amaia Vilas-Zornoza, Patxi San Martin-Uriz, Diego Alignani, Jose Lamo-Espinosa, Mikel San-Julian, Tamara Jiménez-Solas, Felix Lopez, Sandra Muntion, Fermin Sanchez-Guijo, Antonieta Molero, Julia Montoro, Guillermo Serrano, Aintzane Diaz-Mazkiaran, Miren Lasaga, David Gomez-Cabrero, Maria Diez-Campelo, David Valcarcel, Mikel Hernaez, Juan P Romero, Felipe Prosper
Publikováno v:
eLife, Vol 12 (2023)
Early hematopoiesis is a continuous process in which hematopoietic stem and progenitor cells (HSPCs) gradually differentiate toward specific lineages. Aging and myeloid malignant transformation are characterized by changes in the composition and regu
Externí odkaz:
https://doaj.org/article/3e9c063b4a474f658aaf2538b69955f6
Autor:
David Repáraz, Marta Ruiz, Leyre Silva, Belén Aparicio, Josune Egea, Elizabeth Guruceaga, Daniel Ajona, Yaiza Senent, Enrique Conde, Flor Navarro, Sergio Barace, Diego Alignani, Sandra Hervás-Stubbs, Juan José Lasarte, Diana Llopiz, Pablo Sarobe
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Vaccination using optimized strategies may increase response rates to immune checkpoint inhibitors (ICI) in some tumors. To enhance vaccine potency and improve thus responses to ICI, we analyzed the gene expression profile of an immunosuppressive den
Externí odkaz:
https://doaj.org/article/53cc78736e214f2f9fa14856330d5191
Autor:
Jin Ye, Isabel A. Calvo, Itziar Cenzano, Amaia Vilas, Xabier Martinez-de-Morentin, Miren Lasaga, Diego Alignani, Bruno Paiva, Ana C. Viñado, Patxi San Martin-Uriz, Juan P. Romero, Delia Quilez Agreda, Marta Miñana Barrios, Ignacio Sancho-González, Gabriele Todisco, Luca Malcovati, Nuria Planell, Borja Saez, Jesper N. Tegner, Felipe Prosper, David Gomez-Cabrero
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104225- (2022)
Summary: Understanding the regulation of normal and malignant human hematopoiesis requires comprehensive cell atlas of the hematopoietic stem cell (HSC) regulatory microenvironment. Here, we develop a tailored bioinformatic pipeline to integrate publ
Externí odkaz:
https://doaj.org/article/ccde1bb022e24ec1a1f2e788e69807b2
Autor:
Esperanza Martín-Sánchez, Juan José Garcés, Catarina Maia, Susana Inogés, Ascensión López-Díaz de Cerio, Francisco Carmona-Torre, Marta Marin-Oto, Félix Alegre, Elvira Molano, Mirian Fernandez-Alonso, Cristina Perez, Cirino Botta, Aintzane Zabaleta, Ana Belen Alcaide, Manuel F. Landecho, Marta Rua, Teresa Pérez-Warnisher, Laura Blanco, Sarai Sarvide, Amaia Vilas-Zornoza, Diego Alignani, Cristina Moreno, Iñigo Pineda, Miguel Sogbe, Josepmaria Argemi, Bruno Paiva, José Ramón Yuste
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Information on the immunopathobiology of coronavirus disease 2019 (COVID-19) is rapidly increasing; however, there remains a need to identify immune features predictive of fatal outcome. This large-scale study characterized immune responses to severe
Externí odkaz:
https://doaj.org/article/c15b9c99870b4f74b9865fe9dd3e5c42
Autor:
Catarina Maia, Esperanza Martín-Sánchez, Juan José Garcés, Ascensión López-Díaz de Cerio, Susana Inogés, Manuel F. Landecho, Belén Gil-Alzugaray, Cristina Perez, Cirino Botta, Aintzane Zabaleta, Félix Alegre, César Rincón, Laura Blanco, Sarai Sarvide, Amaia Vilas-Zornoza, Diego Alignani, Cristina Moreno, Artur Paiva, António Martinho, Rui Alves, Enrique Colado, Covadonga Quirós, Mónica Olid, Andrés Blanco, Josepmaria Argemi, Bruno Paiva, José Ramón Yuste
Publikováno v:
Haematologica, Vol 106, Iss 5 (2020)
Externí odkaz:
https://doaj.org/article/f714b0cec83e4f249a9d1d18b94f8192
Autor:
Daniel Alameda, Borja Saez, David Lara-Astiaso, Sarai Sarvide, Marta Lasa, Diego Alignani, Idoia Rodriguez, Sonia Garate, Amaia Vilas, Bruno Paiva, Matias Alfonso-Olmos, Jose Maria Lamo de Espinosa, Felipe Prosper, Jesus F. San Miguel, Patricia Maiso
Publikováno v:
Haematologica, Vol 105, Iss 9 (2020)
Externí odkaz:
https://doaj.org/article/229b3097755843fb95fdd43460522b44