Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Diedre M Kavanagh"'
Autor:
Phillip L.R. Nicolson, Sophie H. Nock, Joshua Hinds, Lourdes Garcia-Quintanilla, Christopher W. Smith, Joana Campos, Alexander Brill, Jeremy A. Pike, Abdullah O. Khan, Natalie S. Poulter, Diedre M. Kavanagh, Stephanie Watson, Callum N. Watson, Hayley Clifford, Aarnoud P. Huissoon, Alice Y. Pollitt, Johannes A. Eble, Guy Pratt, Steve P. Watson, Craig E. Hughes
Publikováno v:
Haematologica, Vol 106, Iss 1 (2020)
Inhibitors of the tyrosine kinase Btk have been proposed as novel antiplatelet agents. In this study we show that low concentrations of the Btk inhibitor ibrutinib block CLEC-2-mediated activation and tyrosine phosphorylation including Syk and PLCγ2
Externí odkaz:
https://doaj.org/article/488fe4d4fc05448a940504d50e98e98e
Autor:
Natalie S. Poulter, Joshua Hinds, Alexander Brill, Abdullah O. Khan, Sophie H. Nock, Phillip L R Nicolson, Craig E. Hughes, Joana Campos, Alice Y. Pollitt, Johannes A. Eble, Diedre M Kavanagh, Steve P. Watson, Callum N. Watson, Aarnoud Huissoon, Guy Pratt, Lourdes Garcia-Quintanilla, Christopher W Smith, Hayley Clifford, Stephanie Watson, Jeremy A. Pike
Publikováno v:
Haematologica. 106:208-219
Inhibitors of the tyrosine kinase Btk have been proposed as novel antiplatelet agents. In this study we show that low concentrations of the Btk inhibitor ibrutinib block CLEC-2-mediated activation and tyrosine phosphorylation including Syk and PLCγ2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf28059a9af3a75cc3028f371937372c
https://doi.org/10.3324/haematol.2019.218545
https://doi.org/10.3324/haematol.2019.218545