Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Diederik van Deursen"'
Autor:
Adrie J. M. Verhoeven, Hadie Adams, Hans Jansen, Marije van Leeuwen, Deniz Akdogan, Diederik van Deursen
Publikováno v:
Nutrients, Vol 1, Iss 2, Pp 133-147 (2009)
Polyunsaturated fatty acids affect gene expression mainly through peroxisome proliferator-activated receptors (PPARs) and sterol regulatory element binding proteins (SREBPs), but how monounsaturated fatty acids affect gene expression is poorly unders
Externí odkaz:
https://doaj.org/article/49a9d287b9e94ccf85e50ae08597a8c4
Publikováno v:
British Journal of Nutrition, 103(2), 161-167. Cambridge University Press
The plasma lipid-lowering effect of PUFA, one of their main beneficial effects, is considered to be related to the regulation of lipid biosynthesis through transcription factors including sterol regulatory element binding proteins (SREBP). In the pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a38f6b0e816620a603ad285037579e50
https://doi.org/10.1017/s000711450999167x
https://doi.org/10.1017/s000711450999167x
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1791:229-237
We studied the transcriptional regulation of the HL gene by USF1 and USF2 in HepG2 cells. The transcriptional activity of the HL(− 685/+ 13) promoter construct was increased up to 25-fold by co-transfection with USF1 and USF2. Silencing of USF1 by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1312df347838f1a8deacc45286531090
https://doi.org/10.1016/j.bbalip.2009.01.017
https://doi.org/10.1016/j.bbalip.2009.01.017
Publikováno v:
Molecular and Cellular Endocrinology, 294(1-2), 37-44. Elsevier Ireland Ltd
Molecular and Cellular Endocrinology
Molecular and Cellular Endocrinology, Elsevier, 2008, 294 (1-2), pp.37. ⟨10.1016/j.mce.2008.07.004⟩
Molecular and Cellular Endocrinology
Molecular and Cellular Endocrinology, Elsevier, 2008, 294 (1-2), pp.37. ⟨10.1016/j.mce.2008.07.004⟩
Expression of hepatic lipase (HL) in the liver is reduced during prolonged fasting. This effect is mainly mediated via catecholamines, which signal through elevation of Ca-i(2+) as well as cAMP. We have studied the effect of cAMP on HL expression in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4cbee9c174628e11ea70227d3b37b06
https://doi.org/10.1016/j.mce.2008.07.004
https://doi.org/10.1016/j.mce.2008.07.004
Autor:
Diederik van Deursen, Hans Jansen, Marije van Leeuwen, Hadie Adams, Deniz Akdogan, Adrie J.M. Verhoeven
Publikováno v:
Nutrients; Volume 1; Issue 2; Pages: 133-147
Nutrients, Vol 1, Iss 2, Pp 133-147 (2009)
Nutrients
Nutrients, Vol 1, Iss 2, Pp 133-147 (2009)
Nutrients
Polyunsaturated fatty acids affect gene expression mainly through peroxisome proliferator-activated receptors (PPARs) and sterol regulatory element binding proteins (SREBPs), but how monounsaturated fatty acids affect gene expression is poorly unders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2c6b3fdd370a7a8288845234e26cbb5
Publikováno v:
BMC Genomics, 8. BioMed Central Ltd.
BMC Genomics
BMC Genomics, Vol 8, Iss 1, p 99 (2007)
BMC Genomics
BMC Genomics, Vol 8, Iss 1, p 99 (2007)
Background Mammalian hepatic lipase (HL) genes are transcribed almost exclusively in hepatocytes. The basis for this liver-restricted expression is not completely understood. We hypothesized that the responsible cis-acting elements are conserved amon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75934d7f30cf58f6d89f2ff4e40238b6
https://pure.eur.nl/en/publications/0d7bd5cd-a5eb-4b15-86d8-0db906d03f87
https://pure.eur.nl/en/publications/0d7bd5cd-a5eb-4b15-86d8-0db906d03f87
Autor:
Diederik van Deursen, Gert-Jan Botma, Adrie J.M. Verhoeven, Delfina Vieira, Mandy van Hoek, Hans Jansen
Publikováno v:
Atherosclerosis, 179(1), 61-67. Elsevier Ireland Ltd
Hepatic lipase (HL) not only plays an important role in plasma lipoprotein transport, but may also affect intracellular lipid metabolism. We hypothesize that HL expression is regulated as an integral part of intracellular lipid homeostasis. Addition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb28fdb631773fb31a10c586bf3f9a7a
https://pure.eur.nl/en/publications/ff82e568-5ed0-4759-9341-31d8e089d626
https://pure.eur.nl/en/publications/ff82e568-5ed0-4759-9341-31d8e089d626