Sonic Hedgehog Signaling Promotes Peri-Lesion Cell Proliferation and Functional Improvement after Cortical Contusion Injury

Autor: Ashley K. Pringle, Elshadaie Solomon, Benjamin J. Coles, Brandon R. Desousa, Anan Shtaya, Shyam Gajavelli, Nedal Dabab, Malik J. Zaben, Diederik O. Bulters, M. Ross Bullock, Aminul I. Ahmed

Publikováno v: Neurotrauma Reports, Vol 2, Iss 1, Pp 27-38 (2021)

Traumatic brain injury (TBI) is a leading cause of death and disability globally. No drug treatments are available, so interest has turned to endogenous neural stem cells (NSCs) as alternative strategies for treatment. We hypothesized that regulation

Externí odkaz: https://doaj.org/article/718aa45de3774383adfb2b45270a201e

Risk of Early Versus Later Rebleeding From Dural Arteriovenous Fistulas With Cortical Venous Drainage

Autor: Andrew J. Durnford, Danyal Akarca, David Culliford, John Millar, Ridhima Guniganti, Enrico Giordan, Waleed Brinjikji, Ching-Jen Chen, Isaac Josh Abecassis, Michael Levitt, Adam J. Polifka, Colin P. Derdeyn, Edgar A. Samaniego, Amanda Kwasnicki, Ali Alaraj, Adriaan R.E. Potgieser, Stephanie Chen, Yoshiteru Tada, Ryan Phelps, Adib Abla, Junichiro Satomi, Robert M. Starke, J. Marc C. van Dijk, Sepideh Amin-Hanjani, Minako Hayakawa, Bradley Gross, W. Christopher Fox, Louis Kim, Jason Sheehan, Giuseppe Lanzino, Akash P. Kansagra, Rose Du, Rosalind Lai, Gregory J. Zipfel, Diederik O. Bulters, Jay F. Piccirillo, Hari Raman, Kim Lipsey, Roanna Vine, Harry J. Cloft, David F. Kallmes, Bruce E. Pollock, Michael J. Link, Mohana Rao Patibandla, Dale Ding, Thomas Buell, Gabriella Paisan, R. Michael Meyer, Cory Kelly, Jonathan Duffill, Adam Ditchfield, Jason Macdonald, Dimitri Laurent, Brian Hoh, Jessica Smith, Ashley Lockerman, L. Dade Lunsford, Brian T. Jankowitz, Santiago Ortega Gutierrez, David Hasan, Jorge A. Roa, James Rossen, Waldo Guerrero, Allen McGruder, Fady T. Charbel, Victor A. Aletich, Linda Rose-Finnell, Eric C. Peterson, Dileep R. Yavagal, Samir Sur, Yasuhisa Kanematsu, Nobuaki Yamamoto, Tomoya Kinouchi, Masaaki Korai, Izumi Yamaguchi, Yuki Yamamoto, Ethan Winkler, Michael Lawton, Martin Rutkowski, M. Ali Aziz Sultan, Nirav Patel, Kai U. Frerichs

Publikováno v: Stroke, 53(7), 2340-2345. LIPPINCOTT WILLIAMS & WILKINS
Stroke, vol 53, iss 7

Background: Cranial dural arteriovenous fistulas with cortical venous drainage are rare lesions that can present with hemorrhage. A high rate of rebleeding in the early period following hemorrhage has been reported, but published long-term rates are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f73b31ef28afceb59100e5cdc1306df2
https://research.rug.nl/en/publications/7c2ece23-9cc6-4486-9d83-1393262e471b

Natural history, angiographic presentation and outcomes of anterior cranial fossa dural arteriovenous fistulas

Autor: Sebastian Sanchez, Ashrita Raghuram, Linder Wendt, Minako Hayakawa, Ching-Jen Chen, Jason P Sheehan, Louis J Kim, Isaac Josh Abecassis, Michael R Levitt, R Michael Meyer, Ridhima Guniganti, Akash P Kansagra, Giuseppe Lanzino, Enrico Giordan, Waleed Brinjikji, Diederik O Bulters, Andrew Durnford, W Christopher Fox, Jessica Smith, Adam J Polifka, Bradley Gross, Sepideh Amin-Hanjani, Ali Alaraj, Amanda Kwasnicki, Robert M Starke, Stephanie H Chen, J Marc C van Dijk, Adriaan R E Potgieser, Junichiro Satomi, Yoshiteru Tada, Ryan Phelps, Adib Abla, Ethan Winkler, Rose Du, Pui Man Rosalind Lai, Gregory J Zipfel, Colin Derdeyn, Edgar A Samaniego

Publikováno v: Journal of NeuroInterventional Surgery. :neurintsurg-2022

BackgroundAnterior cranial fossa dural arteriovenous fistulas (ACF-dAVFs) are aggressive vascular lesions. The pattern of venous drainage is the most important determinant of symptoms. Due to the absence of a venous sinus in the anterior cranial foss

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a812d6ba9c6706983e21455ca19f5a4
https://doi.org/10.1136/jnis-2022-019160

Haptoglobin genotype and outcome after spontaneous intracerebral haemorrhage

Autor: Isabel Charlotte, Hostettler, Matthew J, Morton, Gareth, Ambler, Nabila, Kazmi, Tom, Gaunt, Duncan, Wilson, Clare, Shakeshaft, H R, Jäger, Hannah, Cohen, Tarek A, Yousry, Rustam, Al-Shahi Salman, Gregory, Lip, Martin M, Brown, Keith, Muir, Henry, Houlden, Diederik O, Bulters, Ian, Galea, David J, Werring, Emma, Young

Publikováno v: 2020, ' Haptoglobin genotype and outcome after spontaneous intracerebral haemorrhage ', Journal of Neurology, Neurosurgery & Psychiatry . https://doi.org/10.1136/jnnp-2019-321774
J Neurol Neurosurg Psychiatry
Hostettler, I C, Morton, M J, Ambler, G, Kazmi, N, Gaunt, T R, Wilson, D, Shakeshaft, C, Jäger, H R, Cohen, H, Yousry, T, Salman, R A-S, Lip, G Y H, Brown, M, Muir, K W, Houlden, H, Bulters, D O, Galea, I & Werring, D J 2020, ' Haptoglobin genotype and outcome after spontaneous intracerebral haemorrhage ', Journal of Neurology, Neurosurgery, and Psychiatry . https://doi.org/10.1136/jnnp-2019-321774

ObjectiveHaptoglobin is a haemoglobin-scavenging protein that binds and neutralises free haemoglobin and modulates inflammation and endothelial progenitor cell function. A HP gene copy number variation (CNV) generates HP1 and HP2 alleles, while the s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4199c569882babe964a00e923c3c9ec
https://www.pure.ed.ac.uk/ws/files/136449131/REVISED_MANUSCRIPT_Hp_ICH_FINAL_CLEAN.docx

The Wessex modified Richmond Sedation Scale as a novel tool for monitoring patients at risk of malignant MCA syndrome

Autor: Tayyib T A, Hayat, Matthew A, Myers, John, Hell, Matthew, Cordingly, Diederik O, Bulters, Nicolas, Weir, George, Pengas

Publikováno v: Acta neurochirurgica. 160(6)

The Wessex Modified Richmond Sedation Scale (WMRSS) has been developed with the aim of improving the early identification of patients requiring decompressive hemicraniectomy for malignant middle cerebral artery syndrome (MMS). The objective of this s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7b44c08233e61a0a148aff8a263caba8
https://pubmed.ncbi.nlm.nih.gov/29644406