Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Dido Carrero"'
Autor:
Inês Sequeira, Joana F. Neves, Dido Carrero, Qi Peng, Natalia Palasz, Kifayathullah Liakath-Ali, Graham M. Lord, Peter R. Morgan, Giovanna Lombardi, Fiona M. Watt
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Keratin 76 (Krt76) is an epithelial differentiation marker that is downregulated in oral squamous cell carcinomas, correlating with poor prognosis. Here the authors show that genetic ablation of Krt76 in a mouse model results in increased susceptibil
Externí odkaz:
https://doaj.org/article/2887a9969f3b4463a91cb5977cdb295e
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 7, Pp 719-735 (2016)
Ageing is a process that inevitably affects most living organisms and involves the accumulation of macromolecular damage, genomic instability and loss of heterochromatin. Together, these alterations lead to a decline in stem cell function and to a re
Externí odkaz:
https://doaj.org/article/13e4d320814c4a7ab9803a3f905e9744
Autor:
Maria Pascual-Torner, Dido Carrero, José G. Pérez-Silva, Diana Álvarez-Puente, David Roiz-Valle, Gabriel Bretones, David Rodríguez, Daniel Maeso, Elena Mateo-González, Yaiza Español, Guillermo Mariño, José Luis Acuña, Víctor Quesada, Carlos López-Otín
Publikováno v:
Scopus
Turritopsis dohrnii is the only metazoan able to rejuvenate repeatedly after its medusae reproduce, hinting at biological immortality and challenging our understanding of aging. We present and compare whole-genome assemblies of T. dohrnii and the non
Autor:
Peter Morgan, Giovanna Lombardi, Natalia Palasz, Qi Peng, Graham M. Lord, Joana F. Neves, Kifayathullah Liakath-Ali, Fiona M. Watt, Inês Sequeira, Dido Carrero
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Sequeira, I, Neves, J F, Carrero, D, Peng, Q, Palasz, N, Liakath-Ali, K, Lord, G M, Morgan, P R, Lombardi, G & Watt, F M 2018, ' Immunomodulatory role of Keratin 76 in oral and gastric cancer ', Nature Communications, vol. 9, no. 1, 3437 . https://doi.org/10.1038/s41467-018-05872-4
Sequeira, I, Neves, J F, Carrero, D, Peng, Q, Palasz, N, Liakath-Ali, K, Lord, G M, Morgan, P R, Lombardi, G & Watt, F M 2018, ' Immunomodulatory role of Keratin 76 in oral and gastric cancer ', Nature Communications, vol. 9, no. 1, 3437 . https://doi.org/10.1038/s41467-018-05872-4
Keratin 76 (Krt76) is expressed in the differentiated epithelial layers of skin, oral cavity and squamous stomach. Krt76 downregulation in human oral squamous cell carcinomas (OSCC) correlates with poor prognosis. We show that genetic ablation of Krt
Autor:
Filippo Beleggia, Dido Carrero, Raoul C.M. Hennekam, Gonzalo Arboleda, Shehla Mohammed, Mariel Alders, Carlos López-Otín, Gabriele Gillessen-Kaesbach, Jenny Ortega, Gökhan Yigit, Adrián G Sandoval, Alessandro Bruselles, Christian Müller, Janine Altmüller, Stefano Paolacci, Lihadh Al-Gazali, Marco Tartaglia, Humberto Arboleda, Carlos E. Arboleda-Bustos, Débora Romeo Bertola, Bernd Wollnik, Andrea Ciolfi, Yun Li, Antonio Novelli, Emanuele Agolini, Gloria Velasco, Thomas Krieg, Emanuele Bellacchio
Publikováno v:
Journal of medical genetics, 55(12), 837-846. BMJ Publishing Group
BackgroundWiedemann-Rautenstrauch syndrome (WRS) is a form of segmental progeria presenting neonatally, characterised by growth retardation, sparse scalp hair, generalised lipodystrophy with characteristic local fatty tissue accumulations and unusual
Autor:
Dido Carrero, Stephen J. Gaughran, Tomas Marques-Bonet, Isaac Tamargo-Gómez, Scott Glaberman, Miguel G. Álvarez, Kevin P. White, Ylenia Chiari, Zi-Feng Jiang, Adalgisa Caccone, Danielle L. Edwards, Olaya Santiago-Fernández, Joshua M. Miller, Víctor Quesada, María Pascual-Torner, José G. Pérez-Silva, David Roiz-Valle, James P. Gibbs, Gabriel Bretones, Javier R. Arango, Claudio Ciofi, Diana Campos-Iglesias, Carlos López-Otín, Sandra Freitas-Rodríguez, Washington Tapia, Luciano B. Beheregaray, Benjamin R. Evans, Nikos Poulakakis, Miguel Araujo-Voces, Michael A. Russello, Maud C. Quinzin, Pablo Mayoral, Lukas F. K. Kuderna, Danny Rueda, Ryan C. Garrick
Publikováno v:
Nature ecology & evolution
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature ecology & evolution, vol 3, iss 1
Scopus
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
RUO. Repositorio Institucional de la Universidad de Oviedo
Nature Ecology & Evolution
Recercat. Dipósit de la Recerca de Catalunya
Quesada, V; Freitas-Rodríguez, S; Miller, J; Pérez-Silva, JG; Jiang, ZF; Tapia, W; et al.(2019). Giant tortoise genomes provide insights into longevity and age-related disease. Nature Ecology and Evolution, 3(1), 87-95. doi: 10.1038/s41559-018-0733-x. UC Merced: Retrieved from: http://www.escholarship.org/uc/item/8tb9j1g8
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature ecology & evolution, vol 3, iss 1
Scopus
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
RUO. Repositorio Institucional de la Universidad de Oviedo
Nature Ecology & Evolution
Recercat. Dipósit de la Recerca de Catalunya
Quesada, V; Freitas-Rodríguez, S; Miller, J; Pérez-Silva, JG; Jiang, ZF; Tapia, W; et al.(2019). Giant tortoise genomes provide insights into longevity and age-related disease. Nature Ecology and Evolution, 3(1), 87-95. doi: 10.1038/s41559-018-0733-x. UC Merced: Retrieved from: http://www.escholarship.org/uc/item/8tb9j1g8
Giant tortoises are among the longest-lived vertebrate animals and, as such, provide an excellent model to study traits like longevity and age-related diseases. However, genomic and molecular evolutionary information on giant tortoises is scarce. Her
Autor:
Stefano, Paolacci, Yun, Li, Emanuele, Agolini, Emanuele, Bellacchio, Carlos E, Arboleda-Bustos, Dido, Carrero, Debora, Bertola, Lihadh, Al-Gazali, Mariel, Alders, Janine, Altmüller, Gonzalo, Arboleda, Filippo, Beleggia, Alessandro, Bruselles, Andrea, Ciolfi, Gabriele, Gillessen-Kaesbach, Thomas, Krieg, Shehla, Mohammed, Christian, Müller, Antonio, Novelli, Jenny, Ortega, Adrian, Sandoval, Gloria, Velasco, Gökhan, Yigit, Humberto, Arboleda, Carlos, Lopez-Otin, Bernd, Wollnik, Marco, Tartaglia, Raoul C, Hennekam
Publikováno v:
Journal of medical genetics. 55(12)
Wiedemann-Rautenstrauch syndrome (WRS) is a form of segmental progeria presenting neonatally, characterised by growth retardation, sparse scalp hair, generalised lipodystrophy with characteristic local fatty tissue accumulations and unusual face. We
Autor:
Dido Carrero, Joana F. Neves, Kifayathullah Liakath-Ali, Fiona M. Watt, Peter Morgan, Inês Sequeira, Giovanna Lombardi
Publikováno v:
Journal of Investigative Dermatology. 139:S282
Autor:
Carlos López-Otín, Dido Carrero
Publikováno v:
Stem Cell Genetics for Biomedical Research ISBN: 9783319906942
Aging is a process characterized by several alterations, such as accumulation of macromolecular damage, genomic instability, and loss of heterochromatin, which leads to a decline in stem cell function and reduced regenerative capacity. Recently, repr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::136c947821082a98c9634dfae710e15e
https://doi.org/10.1007/978-3-319-90695-9_13
https://doi.org/10.1007/978-3-319-90695-9_13
Autor:
Gloria Velasco, Carlos López-Otín, Nicolas Lévy, Víctor Quesada, Silvia Möhrcken, Annachiara De Sandre-Giovannoli, Dido Carrero, Martina Owens, Raoul C.M. Hennekam, Ana Pérez, Elisabeth Gabau, Diana A. Puente, Óscar Asensio, Wim Wuyts, Valérie Benoit, Clara Soria-Valles, Clea Bárcena, Bart Loeys, Karen Fieggen, Marleen Moens
Publikováno v:
Journal of Medical Genetics
Journal of Medical Genetics, BMJ Publishing Group, 2016, 53 (11), pp.776-785. ⟨10.1136/jmedgenet-2015-103695⟩
Journal of Medical Genetics, 2016, 53 (11), pp.776-785. ⟨10.1136/jmedgenet-2015-103695⟩
Journal of medical genetics, 53(11), 776-785. BMJ Publishing Group
Journal of medical genetics
Journal of Medical Genetics, BMJ Publishing Group, 2016, 53 (11), pp.776-785. ⟨10.1136/jmedgenet-2015-103695⟩
Journal of Medical Genetics, 2016, 53 (11), pp.776-785. ⟨10.1136/jmedgenet-2015-103695⟩
Journal of medical genetics, 53(11), 776-785. BMJ Publishing Group
Journal of medical genetics
International audience; Background Progeroid syndromes are genetic disorders that recapitulate some phenotypes of physiological ageing. Classical progerias, such as Hutchinson-Gilford progeria syndrome (HGPS), are generally caused by mutations in LMN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2a1e0bafa9b56cf00aaace36639d3d4
https://hal.archives-ouvertes.fr/hal-01469060
https://hal.archives-ouvertes.fr/hal-01469060