Výsledky vyhledávání - "Didier Vandier"

Transactivation of the Metallothionein Promoter in Cisplatin-Resistant Cancer Cells: a Specific Gene Therapy Strategy

Autor: Vincent Calvez, Tito Fojo, Didier Vandier, Olivier Rixe, Lyn A. Mickley, Alain Gouyette, Liliane Massade

Publikováno v: JNCI Journal of the National Cancer Institute. 92:642-647

Background Cisplatin (cis-diamminedichloroplatinum) is one of the most active agents against a broad range of malignancies, including ovarian cancer. Cisplatin resistance appears to be associated with several molecular alterations, including overexpr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c2519543e6d0a5ec449cca602e2b790
https://doi.org/10.1093/jnci/92.8.642

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Inhibition of glioma cells in vitro and in vivo using a recombinant adenoviral vector containing an astrocyte-specific promoter

Autor: Didier Vandier, Michael Brenner, Francois Besnard, Kenneth H. Cowan, Merrill E. Goldsmith, Min Kim, Olivier Rixe, Toshiki Rikiyama, Alain Gouyette

Publikováno v: Cancer gene therapy. 7(8)

Gene therapy using the herpes simplex virus thymidine kinase (HSV-TK) gene in combination with the drug ganciclovir (GCV) is a promising approach for the treatment of cancer-inducing gliomas, a tumor with a poor prognosis. In an attempt to limit the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa32b234100b573e7e9b290e2943cffb
https://pubmed.ncbi.nlm.nih.gov/10975672

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