Výsledky vyhledávání - "Didier Thomas"

Akademický článek

The Chávez vote and the national economy in Venezuela

Autor: Nadeau, Richard, Bélanger, Éric, Didier, Thomas

Publikováno v: In Electoral Studies September 2013 32(3):482-488

Structure Activity Relationships of New Inhibitors of Mammalian 2,3-Oxidosqualene Cyclase Designed from Isoquinoline Derivatives

Autor: Jean Binet, Daniel De Fornel, Patrice Renaut, Didier Thomas, Abdellah Benmbarek

Publikováno v: Chemical and Pharmaceutical Bulletin. 50:316-329

We have designed more potent inhibitors from the previously reported LF 05-0038, a 6-isoquinolinol based inhibitor of 2,3-oxidosqualene cyclase (IC50: 1.1 microM). Replacement of the 3-OH group by various 3-substituted amino groups, and modification

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc4780d151d55b9d062ccb6130641614
https://doi.org/10.1248/cpb.50.316

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Differential Utilization of ShcA Tyrosine Residues and Functional Domains in the Transduction of Epidermal Growth Factor-induced Mitogen-activated Protein Kinase Activation in 293T Cells and Nerve Growth Factor-induced Neurite Outgrowth in PC12 Cells

Autor: Didier Thomas, Ralph A. Bradshaw

Publikováno v: Journal of Biological Chemistry. 272:22293-22299

By transient expression of both truncated forms of p52(SHCA) and those with point mutations in 293T cells, it has been shown that, in addition to Tyr-317, Tyr-239/240 is a major site of phosphorylation that serves as a docking site for Grb2.Sos1 comp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9276ee067ae4003988da7b20041b8687
https://doi.org/10.1074/jbc.272.35.22293

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Intracellular acidification mediates the proliferative response of PC12 cells induced by potassium ferricyanide and involves MAP kinase activation

Autor: Stéphane Gaillard, Marie-Françoise Ritz, Didier Thomas, Anant N. Malviya

Publikováno v: International Journal of Cancer. 68:547-552

Potassium ferricyanide is known to elicit cell growth and mitogenesis in various cells by stimulating a transplasma membrane electron-transport system. When serum-starved PC12 cells were treated with potassium ferricyanide, stimulation of mitogenesis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d6c71697674eb7ade20863335f83e188
https://doi.org/10.1002/(sici)1097-0215(19961115)68:4<547::aid-ijc22>3.0.co

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Structural and Stereoelectronic Requirements for the Inhibition of Mammalian 2,3-Oxidosqualene Cyclase by Substituted Isoquinoline Derivatives

Autor: Martine Barth, Patrice Renaut, S. Samreth, Francis Schuber, Jean Binet, Daniel De Fornel, Didier Thomas

Publikováno v: Journal of Medicinal Chemistry. 39:2302-2312

2,3-Oxidosqualene lanosterol-cyclase (OSC; EC 5.4.99.7) is an attractive target for the design of compounds that block hepatic cholesterol biosynthesis. (4a alpha, 5 alpha, 6 beta, 8a beta)-Decahydro-5,8a-dimethyl-2-(1,5,9-trimethyldecyl)-6- isoquino

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbe886c509b1f15ac31d1d33edd8642f
https://doi.org/10.1021/jm9504621

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Truncated presequences of mitochondrial F1-ATPase β subunit from Nicotiana plumbaginifolia transport CAT and GUS proteins into mitochondria of transgenic tobacco

Autor: François Chaumont, S. Leterme, Marc Boutry, Didier Thomas, M de Castro Silva Filho

Publikováno v: Plant Molecular Biology. 24:631-641

The mitochondrial F1-ATPase beta subunit (ATPase-beta) of Nicotiana plumbaginifolia is nucleus-encoded as a precursor containing an NH2-terminal extension. By sequencing the mature N. tabacum ATPase-beta, we determined the length of the presequence,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de98326c07fa78e02ce13340f87644bb
https://doi.org/10.1007/bf00023559

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Differential expression of an endogenous mannose-binding protein R1 during muscle development and regeneration delineating its role in myoblast fusion

Autor: Sylvain Lehmann, Philippe Marschal, Didier Thomas, Jean-Pierre Zanetta, Sabine Kuchler

Publikováno v: Glycobiology. 4:23-38

The role of the endogenous brain carbohydrate-binding protein R1 in muscle cell development and regeneration was analysed both in vivo and in vitro. In vivo, R1 was developmentally regulated, with an embryonic 65,00 subunit and a neonatal 67,000 subu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a34cd33c9f3baa4fd17cd06db08437a6
https://doi.org/10.1093/glycob/4.1.23

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Cerebellar soluble lectin and its glycoprotein ligands in the developing brain of control and dysmyelinating mutant mice

Autor: Jean-Pierre Zanetta, Ali Badache, Guy Vincendon, Sabine Kuchler, Wei-Xia Li, Marlyse Zaepfel, Nicole Baumann, Didier Thomas

Publikováno v: Neurochemistry International. 22:125-133

The levels of an endogenous lectin, the cerebellar soluble lectin (CSL) and of its endogenous glycoprotein ligands were studied using immunoblotting and affinoblotting techniques in the forebrain of quaking, shiverer and jimpy dysmyelinating mutant m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1c08f6904f80eeaa5dd4b1034dfa96b
https://doi.org/10.1016/0197-0186(93)90005-p

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