M-Cadherin Is a PAX3 Target During Myotome Patterning

Autor: Joana Esteves de Lima, Reem Bou Akar, Myriam Mansour, Didier Rocancourt, Margaret Buckingham, Frédéric Relaix

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

PAX3 belongs to the paired-homeobox family of transcription factors and plays a key role as an upstream regulator of muscle progenitor cells during embryonic development. Pax3-mutant embryos display impaired somite development, yet the consequences f

Externí odkaz: https://doaj.org/article/446d015ed7814469b3627db72ea3cc12

Itm2a is a Pax3 target gene, expressed at sites of skeletal muscle formation in vivo.

Autor: Mounia Lagha, Alicia Mayeuf-Louchart, Ted Chang, Didier Montarras, Didier Rocancourt, Antoine Zalc, Jay Kormish, Kenneth S Zaret, Margaret E Buckingham, Frederic Relaix

Publikováno v: PLoS ONE, Vol 8, Iss 5, p e63143 (2013)

The paired-box homeodomain transcription factor Pax3 is a key regulator of the nervous system, neural crest and skeletal muscle development. Despite the important role of this transcription factor, very few direct target genes have been characterized

Externí odkaz: https://doaj.org/article/6f367ee861654522a5bfbfbd3c2986b4

Timed collinear activation of Hox genes during gastrulation controls the avian forelimb position

Autor: Jerome Gros, Chloe Moreau, Didier Rocancourt, Nicolas Denans, Olivier Pourquié, Julian Roussel, Paolo Caldarelli

Publikováno v: Current Biology-CB
Current Biology-CB, Elsevier, 2019, 29 (1), pp.35-50.e4. ⟨10.1101/351106⟩
Current Biology-CB, 2019, 29 (1), pp.35-50.e4. ⟨10.1101/351106⟩

Now published in Current Biology doi: 10.1016/j.cub.2018.11.009; International audience; Limb position along the body is highly consistent within one species but very variable among vertebrates. Despite major advances in our understanding of limb pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a00196a7102cf1c987c9de73e464ecc
https://hal-pasteur.archives-ouvertes.fr/pasteur-01976195

Cell Division Drives Epithelial Cell Rearrangements during Gastrulation in Chick

Autor: Joao Firmino, Didier Rocancourt, Jerome Gros, Mehdi Saadaoui, Chloe Moreau

Publikováno v: Developmental Cell
Developmental Cell, 2016, 36 (3), pp.249-261. ⟨10.1016/j.devcel.2016.01.007⟩
Developmental Cell, Elsevier, 2016, 36 (3), pp.249-261. ⟨10.1016/j.devcel.2016.01.007⟩

International audience; During early embryonic development, cells are organized as cohesive epithelial sheets that are continuously growing and remodeled without losing their integrity, giving rise to a wide array of tissue shapes. Here, using live i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b22895807812e1d0e2c1dd50f9e351f5
https://hal-pasteur.archives-ouvertes.fr/pasteur-01976142

Pax3 regulation of FGF signaling affects the progression of embryonic progenitor cells into the myogenic program

Autor: Jay D. Kormish, Didier Rocancourt, Marie Manceau, Mounia Lagha, Frédéric Relaix, Jonathan A. Epstein, Margaret Buckingham, Kenneth S. Zaret

Publikováno v: Genes & Development; Vol 22
Genes & Development
Genes and Development
Genes and Development, 2008, 22 (13), pp.1828-1837. ⟨10.1101/gad.477908⟩

The balance between stem cell self-renewal and progression into a differentiation program is of critical importance for tissue growth and regeneration. During skeletal muscle development, each muscle contains a pool of resident muscle stem cells that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f3914bbe3ca399408d927a170bf2c0c
https://doi.org/10.1101/gad.477908