Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Didier Philipot"'
Autor:
David Guérit, Didier Philipot, Paul Chuchana, Karine Toupet, Jean-Marc Brondello, Marc Mathieu, Christian Jorgensen, Danièle Noël
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62582 (2013)
The aim of this study was to identify new microRNAs (miRNAs) that are modulated during the differentiation of mesenchymal stem cells (MSCs) toward chondrocytes. Using large scale miRNA arrays, we compared the expression of miRNAs in MSCs (day 0) and
Externí odkaz:
https://doaj.org/article/631868b9e62d40149e93799603666b41
Autor:
Didier Philipot, Jean-Marc Brondello, Christian Jorgensen, Claire Bony, Karine Toupet, Paul Chuchana, David Guérit, Danièle Noël
Publikováno v:
Stem Cells and Development
Stem Cells and Development, Mary Ann Liebert, 2014, 23 (11), pp.1195-1205. ⟨10.1089/scd.2013.0463⟩
Stem Cells and Development, Mary Ann Liebert, 2014, 23 (11), pp.1195-1205. ⟨10.1089/scd.2013.0463⟩
International audience; Skeletal development and cartilage formation require stringent regulation of gene expression for mesenchymal stem cells (MSCs) to progress through stages of differentiation. Since microRNAs (miRNAs) regulate biological process
Publikováno v:
The Open Rheumatology Journal. 4:10-14
Objective This study aims at highlighting the common signature between cartilaginous tissue in osteoarthritis (OA) and preneoplasic tissues preceding neoplasia and tumour formation and, second, focusing on the molecular mechanisms at the aetiology of
Autor:
Jean-Marc, Brondello, Alexandre, Prieur, Didier, Philipot, Jean-Marc, Lemaitre, Guy, Lenaers, Jacques, Piette, Vjekoslav, Dulić
Publikováno v:
Medecine sciences : M/S. 28(3)
Cellular senescence is, essentially, a permanent proliferation arrest induced by various cellular stresses or inappropriate stimuli. This arrest, which is associated with dramatic changes in cell morphology, metabolism and gene expression, involves a
Autor:
Rosa Maria Borzì, Didier Philipot, Eleonora Olivotto, Danièle Noël, Paul Chuchana, Christian Jorgensen, Jean-Marc Brondello, Jacques Piette, Daniela Platano, David Guérit
Publikováno v:
Osteoarthritis and Cartilage. 20
Publikováno v:
The Open Rheumatology Journal
Objective: This study aims at highlighting the common signature between cartilaginous tissue in osteoarthritis (OA) and preneoplasic tissues preceding neoplasia and tumour formation and, second, focusing on the molecular mechanisms at the aetiology o
Autor:
Paul Chuchana, Jacques Piette, Christian Jorgensen, Didier Philipot, Eleonora Olivotto, Anne Dorandeu, Yves-Marie Pers, David Guérit, Danièle Noël, Francisco Espinoza, Jean-Marc Brondello, Daniela Platano, Rosa Maria Borzì
Publikováno v:
Arthritis Research & Therapy
Arthritis Research and Therapy
Arthritis Research and Therapy, BioMed Central, 2014, 16 (1), pp.R58. ⟨10.1186/ar4494⟩
Arthritis Research and Therapy, 2014, 16 (1), pp.R58. ⟨10.1186/ar4494⟩
Arthritis Research and Therapy
Arthritis Research and Therapy, BioMed Central, 2014, 16 (1), pp.R58. ⟨10.1186/ar4494⟩
Arthritis Research and Therapy, 2014, 16 (1), pp.R58. ⟨10.1186/ar4494⟩
Introduction Recent evidence suggests that tissue accumulation of senescent p16INK4a-positive cells during the life span would be deleterious for tissue functions and could be the consequence of inherent age-associated disorders. Osteoarthritis (OA)
Autor:
Christian Jorgensen, Jean-Marc Brondello, Danièle Noël, Didier Philipot, David Guérit, Paul Chuchana
Publikováno v:
Annals of the Rheumatic Diseases. 71:A65.3-A66
Backgroundand objectives Mesenchymal stem or stromal cells (MSC) are multipotent cells that can differentiate into different lineages, particularly osteoblasts and chondrocytes. The differentiation process of MSC is regulated by various molecules amo
Autor:
Christian Jorgensen, Daniela Platano, Eleonora Olivotto, Didier Philipot, David Guérit, Paul Chuchana, Jacques Piette, Danièle Noël, Jean-Marc Brondello, Rosa Maria Borzì
Publikováno v:
Annals of the Rheumatic Diseases. 71:A66.2-A67
Backgroundand objectives Osteoarthritic (OA) chondrocyte is characterised by altogether DNA damage accumulation, eroded telomeres, expression of senescence marker such as p16 Ink4a and establishment of one specific secretome including IL-1b, IL-8 and