Výsledky vyhledávání - "Didier Heumann"

The dual role of LBP and CD14 in response to Gram-negative bacteria or Gram-negative compounds

Autor: Didier Heumann, Bernard Ryffel, Roger Lauener

Publikováno v: Journal of endotoxin research.
Journal of endotoxin research., 2003, 9, pp.281-284

Innate immunity initiates protection of the host organism against invasion of micro-organisms by specific recognition mechanisms. This article reviews the dual role of LBP/CD14 in innate immunity, focusing mostly on experiments performed in mice by t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e259e5af22a93b6b50d4c27d0cc81aa
https://doi.org/10.1177/09680519030090061201

Zobrazit plný text záznamu

Hyperlipoproteinemic low-density lipoprotein receptor-deficient mice are more susceptible to sepsis than corresponding wild-type mice

Autor: Susan Lanza-Jacoby, John T. Flynn, Alexander G. Minchenko, Didier Heumann, Shushan Jacob, Sheldon Miller

Publikováno v: Journal of Endotoxin Research. 9:341-347

High circulating concentrations of lipoproteins have been shown to modify the cytokine response and reduce mortality after endotoxin or live bacterial challenge. Sepsis, however, is more complex than endotoxemia, and it is not clear whether elevated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::412a8d32adebc4670cdc12382ebab502
https://doi.org/10.1177/09680519030090060701

Zobrazit plný text záznamu

Teichoic Acids Are Not Required forStreptococcus pneumoniaeandStaphylococcus aureusCell Walls To Trigger the Release of Tumor Necrosis Factor by Peripheral Blood Monocytes

Autor: Paul Majcherczyk, Philippe Moreillon, Didier Heumann, M. P. Glauser, E. Rubli

Publikováno v: Infection and Immunity. 71:3707-3713

In gram-negative bacteria, the outer membrane lipopolysaccharide is the main component triggering cytokine release from peripheral blood mononuclear cells (PBMCs). In gram-positive bacteria, purified walls also induce cytokine release, but stimulatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44c40621ab8a5a03454de88059f54edd
https://doi.org/10.1128/iai.71.7.3707-3713.2003

Zobrazit plný text záznamu

Augmentation of the Lipopolysaccharide-Neutralizing Activities of Human Cathelicidin CAP18/LL-37-Derived Antimicrobial Peptides by Replacement with Hydrophobic and Cationic Amino Acid Residues

Autor: Michimasa Hirata, Isao Nagaoka, Shigenori Tanaka, Satoko Hirota, Didier Heumann, Yoshiyuki Adachi, Hiroshi Tamura, François Niyonsaba

Publikováno v: Clinical and Vaccine Immunology. 9:972-982

Mammalian myeloid and epithelial cells express various peptide antibiotics (such as defensins and cathelicidins) that contribute to the innate host defense against invading microorganisms. Among these peptides, human cathelicidin CAP18/LL-37 (L1to S3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a30b55a22b448e3f93ab0af9243b35de
https://doi.org/10.1128/cdli.9.5.972-982.2002

Zobrazit plný text záznamu

Initial responses to endotoxins and Gram-negative bacteria

Autor: Didier Heumann, Thierry Roger

Publikováno v: Clinica Chimica Acta. 323:59-72

The innate immune system initiates host defence against invasive microbial pathogens using specific recognition mechanisms. Here we review the current concepts and the molecular basis of innate immune responses to bacterial infections, focusing our a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::622039c4272237a829baa7fb44b0e67f
https://doi.org/10.1016/s0009-8981(02)00180-8

Zobrazit plný text záznamu

Critical Role of Lipopolysaccharide-Binding Protein and CD14 in Immune Responses against Gram-Negative Bacteria

Autor: Didier Le Roy, Yoshiyuki Adachi, Didier Heumann, Franco Di Padova, Thierry Calandra, Michel P. Glauser

Publikováno v: The Journal of Immunology. 167:2759-2765

LPS-binding protein (LBP) and CD14 potentiate cell activation by LPS, contributing to lethal endotoxemia. We analyzed the contribution of LBP/CD14 in models of bacterial infection. Mice pretreated with mAbs neutralizing CD14 or LBP showed a delay in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c80c7adbcbaff75b8067c2683c400013
https://doi.org/10.4049/jimmunol.167.5.2759

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání