Výsledky vyhledávání - "Didier Goedertier"

Use of Capillary Aerosol Generator in Continuous Production of Controlled Aerosol for Non-Clinical Studies

Autor: Julia Hoeng, Arkadiusz K. Kuczaj, Patrick Vanscheeuwijck, Subash Krishnan, Falk Radtke, Wei Teck Tan, Tom Lee, Francesco Lucci, Sandra Schorderet Weber, Didier Goedertier

Publikováno v: Journal of Visualized Experiments.

The capillary aerosol generator (CAG) is operated with the principal of thermal liquid evaporation through heating of e-liquid in the initial phase, followed by nucleation and condensation regulated through a mixture of airflow to generate aerosols,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bc026716c884fcea5c645b747f2fd78
https://doi.org/10.3791/61021-v

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State-of-the-art methods and devices for generation, exposure, and collection of aerosols from e-vapor products

Autor: Carole Mathis, Patrick Vanscheeuwijck, Wei Teck Tan, Anita R. Iskandar, Blaine Phillips, Diego Marescotti, Walter K. Schlage, Anne May, Manuel C. Peitsch, Davide Sciuscio, Stéphanie Boué, Didier Goedertier, Arkadiusz K. Kuczaj, Julia Hoeng

Publikováno v: Toxicology Research and Application, Vol 4 (2020)

E-vapor products (EVP) have become popular alternatives for cigarette smokers who would otherwise continue to smoke. EVP research is challenging and complex, mostly because of the numerous and rapidly evolving technologies and designs as well as the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffc5d140978d110e8d064460e1ff5483
https://doaj.org/article/1e4c1abc007845a3803bc03ff88b4aac

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State-of-the-art methods and devices for the generation, exposure, and collection of aerosols from heat-not-burn tobacco products

Autor: Carole Mathis, Manuel C. Peitsch, Arkadiusz K. Kuczaj, Wei Teck Tan, Shoaib Majeed, Anne May, Falk Radtke, Didier Goedertier, Julia Hoeng, Stéphanie Boué, Walter K. Schlage, Blaine Phillips, Patrick Vanscheeuwijck

Publikováno v: Toxicology Research and Application, Vol 4 (2020)

Tobacco harm reduction is increasingly recognized as a promising approach to accelerate the decline in smoking prevalence and smoking-related population harm. Potential modified risk tobacco products (MRTPs) must undergo a rigorous premarket toxicolo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8880f17f2a8a4b0a59ecc28c9a6dc3c
https://doi.org/10.1177/2397847319897869

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In vitro systems toxicology-based assessment of the potential modified risk tobacco product CHTP 1.2 for vascular inflammation- and cytotoxicity-associated mechanisms promoting adhesion of monocytic cells to human coronary arterial endothelial cells

Autor: Dariusz Peric, Claudius Pak, Stefano Acali, David Bornand, Julia Hoeng, Emmanuel Guedj, Athanasios Kondylis, Nikolai V. Ivanov, Elodie Maluenda, Didier Goedertier, Alexandra Laurent, Ignacio Gonzalez Suarez, Karine Baumer, Remi Dulize, Diego Marescotti, Marco van der Toorn, Manuel C. Peitsch, Carine Poussin, Walter K. Schlage

Publikováno v: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 120

Cigarette smoking causes cardiovascular diseases. Heating tobacco instead of burning it reduces the amount of toxic compounds in the aerosol and may exert a reduced impact on health compared with cigarette smoke. Aqueous extract from the aerosol of a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e99f1474dd47de099361a9f0e58a7ea
https://pubmed.ncbi.nlm.nih.gov/30026091

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A prototypic modified risk tobacco product exhibits reduced effects on chemotaxis and transendothelial migration of monocytes compared with a reference cigarette

Autor: Julia Hoeng, Manuel C. Peitsch, Marco van der Toorn, Didier Goedertier, Stefan Frentzel, Hector De Leon

Publikováno v: Food and Chemical Toxicology. 80:277-286

Monocyte adhesion and migration to the subendothelial space represent critical steps in atherogenesis. Here, we investigated whether extracts from the aerosol of a prototypic modified risk tobacco product (pMRTP), based on heating rather than combust

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::992685d6b39f7caced486867020f7df7
https://doi.org/10.1016/j.fct.2015.03.026

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In Vitro Systems Toxicology Assessment of a Candidate Modified Risk Tobacco Product Shows Reduced Toxicity Compared to That of a Conventional Cigarette

Autor: Stefano Acali, Didier Goedertier, Stefan Frentzel, Stephanie Johne, Ignacio Gonzalez-Suarez, Nikolai V. Ivanov, Florian Martin, Manuel C. Peitsch, Remi Dulize, Emmanuel Guedj, Julia Hoeng, Karine Baumer, Carole Mathis, Dariusz Peric, Diego Marescotti

Publikováno v: Chemical research in toxicology. 29(1)

Cigarette smoke increases the risk for respiratory and other diseases. Although smoking prevalence has declined over the years, millions of adults choose to continue to smoke. Modified risk tobacco products (MRTPs) are potentially valuable tools for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cb83499263b199e8a75b8d010210ce7
https://pubmed.ncbi.nlm.nih.gov/26651182

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Biological impact of cigarette smoke compared to an aerosol produced from a prototypic modified risk tobacco product on normal human bronchial epithelial cells

Autor: Eric Dossin, Yang Xiang, Carole Mathis, I. Gonzalez Suarez, Manuel C. Peitsch, Florian Martin, Diego Marescotti, U. Kogel, Didier Goedertier, Julia Hoeng, Philippe A. Guy

Publikováno v: Toxicology in vitro : an international journal published in association with BIBRA. 29(8)

Cigarette smoking causes serious and fatal diseases. The best way for smokers to avoid health risks is to quit smoking. Using modified risk tobacco products (MRTPs) may be an alternative to reduce the harm caused for those who are unwilling to quit s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df7ed2879b59b267d1b35fb036ec9c61
https://pubmed.ncbi.nlm.nih.gov/26277032

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