Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Didier Fradelizi"'
Autor:
Gilles Renault, Didier Fradelizi, Gaëlle Clavel, Natacha Bessis, Carmen Marchiol-Fournigault, MC Boissier
Publikováno v:
Annals of the Rheumatic Diseases. 67:1765-1772
Objectives: The evaluation of joints in arthritis using conventional ultrasonography is not really feasible in mice because of the small size of the animal. However, compared with classical analysis (clinical and histological examination) it is a non
Autor:
Didier Fradelizi, M. Luisa Gil, José-Enrique O'Connor, Daniel Gozalbo, M.Luisa Ferrándiz, Patricia Roig, Eva Villamón
Publikováno v:
Microbes and Infection. 6:542-548
Previous work by our group showed that Toll-like receptor 2 (TLR2) is essential for activation of innate immunity, playing a major role in the response of macrophages to Candida albicans, triggering cytokine and chemokine expression, and therefore TL
Autor:
Didier Fradelizi, Eva Villamón, Daniel Gozalbo, M. Luisa Gil, Patricia Roig, José-Enrique O'Connor
Publikováno v:
ResearcherID
In this work, we studied the role of toll-like receptor-2 (TLR2) in murine defenses against Candida albicans. TLR2-deficient mice experimentally infected intraperitoneally (i.p.) or intravenously (i.v.) in vivo had very significant impaired survival
Publikováno v:
Journal of Virology. 76:633-643
It is becoming apparent that over the years cell infection by virus seems to have evolved into a multistep process in which many viruses employ distinct cell surface molecules for their attachment and cell entry. In this study the attachment and entr
Publikováno v:
Human Immunology. 62:764-770
Glucose regulated protein 78 (GRP78) is a member of the heat shock protein (hsp) 70 family. It is an endoplasmic reticulum (ER) chaperone, whose function is generally thought to be limited to the structural maturation of nascent glycoproteins. Howeve
Autor:
Annunciata Vecchi, Alberto Mantovani, Natacha Bessis, Marie-Christophe Boissier, Laurence Guéry, John E. Sims, Didier Fradelizi
Publikováno v:
European Journal of Immunology. 30:867-875
IL-1 is a key cytokine involved in the inflammatory response. The type II receptor of IL-1 (IL-1RII) acts as a decoy receptor, binding and inhibiting the effect of IL-1. This study was undertaken to establish whether IL-1RII can ameliorate collagen-i
Autor:
Natacha Bessis, J. Honiger, A. Minty, Diane Damotte, Didier Fradelizi, Catherine Fournier, Marie-Christophe Boissier
Publikováno v:
Clinical and Experimental Immunology. 117:376-382
SUMMARYA strategy of gene therapy using IL-4 or IL-13 xenogeneic transfected cells encapsulated into permeable hollow fibres (HF) was used to treat CIA. Hydrogel-based hollow fibres were obtained from AN-69 copolymer, already known for its biocompati
Publikováno v:
Clinical and Experimental Immunology. 114:284-292
SUMMARYWe have examined the capacity of peripheral blood T cells from RA patients to be polarized in vitro towards a type 1 (T1) or a type 2 (T2) phenotype. Peripheral blood T cells from RA patients and from healthy donors were primed by 1 week of cu
Autor:
Francesca Fioretti, Didier Fradelizi, Antonella Stoppacciaro, Simona Ramponi, Luigi Ruco, Adrian Minty, Silvano Sozzani, Cecilia Garlanda, Annunciata Vecchi, Alberto Mantovani
Publikováno v:
The Journal of Immunology. 161:342-346
Monocyte chemotactic protein-3 (MCP-3) is a C-C chemokine that interacts with the CCR1, CCR2, and CCR3 receptors and has a spectrum of action encompassing T cells, NK cells, eosinophils, and dendritic cells (DC), in addition to mononuclear phagocytes
Autor:
Didier Fradelizi, Jacques Thèze
Publikováno v:
Annales de l'Institut Pasteur / Actualités. 9:95-106
Les cytokines sont de petites molecules qui assurent la communication intercellulaire dans differents systemes biologiques. Les cytokines du systeme immunitaire parfois appelees interleukines, lymphokines, monokines, interferons immunitaires jouent u