Výsledky vyhledávání - "Didier Filopon"

A Legionella pneumophila effector impedes host gene silencing to promote virulence

Autor: Justine Toinon, Monica Rolando, Magali Charvin, Didier Filopon, Lionel Schiavolin, Khadeeja Adam Sy, Hai-Chi Vu, Sarah Gallois-Montbrun, Antoine Alam, Christophe Rusniok, Bérangère Lombard, Damarys Loew, Carmen Buchrieser, Lionel Navarro

RNA silencing is a gene silencing mechanism directed by siRNAs and miRNAs. Human miRNAs act as central regulators of host-bacteria interactions. However, it is unknown whether human pathogenic bacteria could impede RNA silencing to promote virulence.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95071a907ff9ad9d953181fe0ac03ecc
https://hal.science/hal-03874249/file/2022.11.16.516792v1.full.pdf

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Identification of a Brucella spp. secreted effector specifically interacting with human small GTPase Rab2

Autor: Alexandre Muller, Jean-Jacques Letesson, Didier Filopon, Suzana P. Salcedo, Jean-Claude Twizere, Cécile Nicolas, Alexandre Jamet, Jean Vandenhaute, Xavier De Bolle, Marie de Barsy, Jean-Pierre Gorvel, Jean François Rual, Géraldine Laloux, David E. Hill, Bernard Nkengfac

Publikováno v: Cellular Microbiology. 13:1044-1058

Bacteria of the Brucella genus are facultative intracellular class III pathogens. These bacteria are able to control the intracellular trafficking of their vacuole, presumably by the use of yet unknown translocated effectors. To identify such effecto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::084f4c28ce4f669a7720d9179e26e23e
https://doi.org/10.1111/j.1462-5822.2011.01601.x

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Optimization of a Type III Secretion System-Based Pseudomonas aeruginosa Live Vector for Antigen Delivery

Autor: Carole Margerit, Madiha Derouazi, Olivier Epaulard, Didier Filopon, Raphaël Marlu, Benoît Polack, Bertrand Toussaint

Publikováno v: Clinical and Vaccine Immunology
Clinical and Vaccine Immunology, American Society for Microbiology, 2008, 15 (2), pp.308-13. ⟨10.1128/CVI.00278-07⟩

During the last few years, the use of type III secretion system-based bacterial vectors for immunotherapy purposes has been assessed in various applications. We showed that a type III secretion-based Pseudomonas aeruginosa vector delivering the ovalb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b49b135ed8315a557971d59ed8462e8c
https://doi.org/10.1128/cvi.00278-07

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High-cell-density regulation of the Pseudomonas aeruginosa type III secretion system: implications for tryptophan catabolites

Autor: Madiha Derouazi, Hichem Chaker, Didier Filopon, Stephanie Boullanger, Benoît Polack, Da-Kang Shen, Bertrand Toussaint

Publikováno v: Microbiology
Microbiology, Microbiology Society, 2008, 154 (8), pp.2195-208. ⟨10.1099/mic.0.2007/013680-0⟩
Microbiology-Sgm
Microbiology-Sgm, 2008, pp.2195-2208

International audience; The Pseudomonas aeruginosa type III secretion system (T3SS) is known to be a very important virulence factor in acute human infections, but it is less important in maintaining chronic infections in which T3SS genes are downreg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e20a0e21ad1472d3d791050bda52f3a
https://hal.archives-ouvertes.fr/hal-00381578

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Epigenetic acquisition of inducibility of type III cytotoxicity in P. aeruginosa

Autor: Rozenne LeBerre, Gilles Bernot, Benoit Guery, Didier Filopon, Benoît Polack, Jean-Paul Comet, Janine Guespin-Michel, Annabelle Merieau

Publikováno v: BMC Bioinformatics
BMC Bioinformatics, 2006, 7, pp.272. ⟨10.1186/1471-2105-7-272⟩
BMC Bioinformatics, BioMed Central, 2006, 7, pp.272--282. ⟨10.1186/1471-2105-7-272⟩
BMC Bioinformatics, Vol 7, Iss 1, p 272 (2006)
BMC Bioinformatics, BioMed Central, 2006, 7, pp.272. ⟨10.1186/1471-2105-7-272⟩

Background Pseudomonas aeruginosa, an opportunistic pathogen, is often encountered in chronic lung diseases such as cystic fibrosis or chronic obstructive pneumonia, as well as acute settings like mechanical ventilation acquired pneumonia or neutrope

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::761c45848c37f2a029118871c687a251
https://hal.science/hal-00381910/document

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MECANISMES DE REGULATION IMPLIQUES DANS LA PATHOGENICITE DE PSEUDOMONAS AERUGINOSA : SYSTEME DE SECRETION DE TYPE III, EPIGENESE ET QUORUM SENSING

Autor: Didier Filopon

Publikováno v: Autre [q-bio.OT]. Université Joseph-Fourier-Grenoble I, 2005. Français
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Pseudomonas aeruginosa is an opportunistic bacterium responsible for severe infections. Its pathogenicity comes from many virulence factors including the type III secretion system (TTSS). This system is activated by contact between the cell and the b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::57eef479606756cf12c36051f2f6353f
https://tel.archives-ouvertes.fr/tel-00011459

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Approche logique, bio-informatique et expérimentale de la dynamique d'un réseau de régulation chez Pseudomonas aeruginosa

Autor: Janine Guespin, Didier Filopon, Annabelle Mérieau, Gilles Bernot, Jean-Paul Comet, Benoît Polack

Publikováno v: Réunion satellite des Journée Ouvertes Biologie Informatique Mathématiques (JOBIM) : <>
Réunion satellite des Journée Ouvertes Biologie Informatique Mathématiques (JOBIM) :, 2005, France
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Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ef44c673e5e146a6c1bb91988831f02e
https://hal.science/hal-00342084

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