Zobrazeno 1 - 10
of 192
pro vyhledávání: '"Didier Boturyn"'
Autor:
Justyna Ciolek, Claude Zoukimian, Justine Dhot, Mélanie Burban, Mathilde Triquigneaux, Benjamin Lauzier, Christelle Guimbert, Didier Boturyn, Marine Ferron, Lidia Ciccone, Livia Tepshi, Enrico Stura, Pierre Legrand, Philippe Robin, Gilles Mourier, Béatrice Schaack, Imen Fellah, Guillaume Blanchet, Chantal Gauthier-Erfanian, Rémy Beroud, Denis Servent, Michel De Waard, Nicolas Gilles
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 150, Iss , Pp 113094- (2022)
All five muscarinic receptors have important physiological roles. The endothelial M2 and M3 subtypes regulate arterial tone through direct coupling to Gq or Gi/o proteins. Yet, we lack selective pharmacological drugs to assess the respective contribu
Externí odkaz:
https://doaj.org/article/81fb19f4b1464cb2be0363e9765a0645
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 525 (2023)
RGD peptides have received a lot of attention over the two last decades, in particular to improve tumor therapy through the targeting of the αVβ3 integrin receptor. This review focuses on the molecular design of multimeric RGD compounds, as well as
Externí odkaz:
https://doaj.org/article/59c12df03fb24d1e814e73ea9fd35e2b
Autor:
Zhao-Hui Jin, Atsushi B. Tsuji, Mélissa Degardin, Pascal Dumy, Didier Boturyn, Tatsuya Higashi
Publikováno v:
Cells, Vol 11, Iss 21, p 3499 (2022)
pH (low) insertion peptides (pHLIPs) have been developed for cancer imaging and therapy targeting the acidic extracellular microenvironment. However, the characteristics of intratumoral distribution (ITD) of pHLIPs are not yet fully understood. This
Externí odkaz:
https://doaj.org/article/5d0af2a4a582471eb1cfafa9f71406c9
Autor:
Oliver Brun, Claude Zoukimian, Barbara Oliveira-Mendes, Jérôme Montnach, Benjamin Lauzier, Michel Ronjat, Rémy Béroud, Frédéric Lesage, Didier Boturyn, Michel De Waard
Publikováno v:
Toxins, Vol 14, Iss 2, p 79 (2022)
α-bungarotoxin is a large, 74 amino acid toxin containing five disulphide bridges, initially identified in the venom of Bungarus multicinctus snake. Like most large toxins, chemical synthesis of α-bungarotoxin is challenging, explaining why all pre
Externí odkaz:
https://doaj.org/article/d2b5f17dd06b4fd9980cd477e3fd9b7b
Autor:
Sofia Kajouj, Lionel Marcelis, Alice Mattiuzzi, Adrien Grassin, Damien Dufour, Pierre Van Antwerpen, Didier Boturyn, Eric Defrancq, Mathieu Surin, Julien De Winter, Pascal Gerbaux, Ivan Jabin, Cécile Moucheron
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 1758-1768 (2018)
Photoactive ruthenium-based complexes are actively studied for their biological applications as potential theragnostic agents against cancer. One major issue of these inorganic complexes is to penetrate inside cells in order to fulfil their function,
Externí odkaz:
https://doaj.org/article/ed82aefa2b9b4543a7d84e8115ecbfaa
Autor:
Zhao-Hui Jin, Atsushi B. Tsuji, Mélissa Degardin, Aya Sugyo, Yukie Yoshii, Kotaro Nagatsu, Ming-Rong Zhang, Yasuhisa Fujibayashi, Pascal Dumy, Didier Boturyn, Tatsuya Higashi
Publikováno v:
EJNMMI Research, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Background The present study proposed a new concept for targeted radionuclide therapy (TRT) to improve the intratumoral distribution of radioactivity using two different radiopharmaceuticals. We examined the efficacy of a combination of a te
Externí odkaz:
https://doaj.org/article/8b0bf5d5939249e6adaaf9de3eb3dad2
Publikováno v:
Molecules, Vol 25, Iss 8, p 1998 (2020)
Bacterial resistance is becoming a global issue due to its rapid growth. Potential new drugs as antimicrobial peptides (AMPs) are considered for several decades as promising candidates to circumvent this threat. Nonetheless, AMPs have also been used
Externí odkaz:
https://doaj.org/article/eb130a053acb4d4eb7a232d905720773
Autor:
Sébastien Nicolas, Claude Zoukimian, Frank Bosmans, Jérôme Montnach, Sylvie Diochot, Eva Cuypers, Stephan De Waard, Rémy Béroud, Dietrich Mebs, David Craik, Didier Boturyn, Michel Lazdunski, Jan Tytgat, Michel De Waard
Publikováno v:
Toxins, Vol 11, Iss 6, p 367 (2019)
Phlotoxin-1 (PhlTx1) is a peptide previously identified in tarantula venom (Phlogius species) that belongs to the inhibitory cysteine-knot (ICK) toxin family. Like many ICK-based spider toxins, the synthesis of PhlTx1 appears particularly challenging
Externí odkaz:
https://doaj.org/article/e86d22f9474449df85156f8c0d4cf8f5
Autor:
Winn Aung, Zhao-Hui Jin, Takako Furukawa, Michael Claron, Didier Boturyn, Chizuru Sogawa, Atsushi B. Tsuji, Hidekatsu Wakizaka, Toshimitsu Fukumura, Yasuhisa Fujibayashi, Pascal Dumy, Tsuneo Saga
Publikováno v:
Molecular Imaging, Vol 12 (2013)
The purpose of this study was to develop a clinically relevant orthotopic xenotransplantation model of pancreatic cancer and to perform a preclinical evaluation of a new positron emission tomography (PET) imaging probe, 64 Cu-labeled cyclam-RAFT-c(-R
Externí odkaz:
https://doaj.org/article/67845eb1784e410a860d6316707620c0
Autor:
Zhao-Hui Jin, Jesus Razkin, Veronique Josserand, Didier Boturyn, Alexeï Grichine, Isabelle Texier, Marie-Christine Favrot, Pascal Dumy, Jean-Luc Coll
Publikováno v:
Molecular Imaging, Vol 6 (2007)
We reported that regioselectively addressable functionalized template (RAFT)-c(-RGDfK-) 4 presenting four cyclic (Arg-Gly-Asp) (cRGD) peptides targets integrin a V b 3 with an improved specificity compared with monomeric cRGD. In this study, we impro
Externí odkaz:
https://doaj.org/article/8fa4743c8b9541aa96bfca0dd0c2783d