Zobrazeno 1 - 10
of 192
pro vyhledávání: '"Didier, Boturyn"'
Autor:
Justyna Ciolek, Claude Zoukimian, Justine Dhot, Mélanie Burban, Mathilde Triquigneaux, Benjamin Lauzier, Christelle Guimbert, Didier Boturyn, Marine Ferron, Lidia Ciccone, Livia Tepshi, Enrico Stura, Pierre Legrand, Philippe Robin, Gilles Mourier, Béatrice Schaack, Imen Fellah, Guillaume Blanchet, Chantal Gauthier-Erfanian, Rémy Beroud, Denis Servent, Michel De Waard, Nicolas Gilles
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 150, Iss , Pp 113094- (2022)
All five muscarinic receptors have important physiological roles. The endothelial M2 and M3 subtypes regulate arterial tone through direct coupling to Gq or Gi/o proteins. Yet, we lack selective pharmacological drugs to assess the respective contribu
Externí odkaz:
https://doaj.org/article/81fb19f4b1464cb2be0363e9765a0645
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 525 (2023)
RGD peptides have received a lot of attention over the two last decades, in particular to improve tumor therapy through the targeting of the αVβ3 integrin receptor. This review focuses on the molecular design of multimeric RGD compounds, as well as
Externí odkaz:
https://doaj.org/article/59c12df03fb24d1e814e73ea9fd35e2b
Autor:
Zhao-Hui Jin, Atsushi B. Tsuji, Mélissa Degardin, Pascal Dumy, Didier Boturyn, Tatsuya Higashi
Publikováno v:
Cells, Vol 11, Iss 21, p 3499 (2022)
pH (low) insertion peptides (pHLIPs) have been developed for cancer imaging and therapy targeting the acidic extracellular microenvironment. However, the characteristics of intratumoral distribution (ITD) of pHLIPs are not yet fully understood. This
Externí odkaz:
https://doaj.org/article/5d0af2a4a582471eb1cfafa9f71406c9
Autor:
Oliver Brun, Claude Zoukimian, Barbara Oliveira-Mendes, Jérôme Montnach, Benjamin Lauzier, Michel Ronjat, Rémy Béroud, Frédéric Lesage, Didier Boturyn, Michel De Waard
Publikováno v:
Toxins, Vol 14, Iss 2, p 79 (2022)
α-bungarotoxin is a large, 74 amino acid toxin containing five disulphide bridges, initially identified in the venom of Bungarus multicinctus snake. Like most large toxins, chemical synthesis of α-bungarotoxin is challenging, explaining why all pre
Externí odkaz:
https://doaj.org/article/d2b5f17dd06b4fd9980cd477e3fd9b7b
Autor:
Sofia Kajouj, Lionel Marcelis, Alice Mattiuzzi, Adrien Grassin, Damien Dufour, Pierre Van Antwerpen, Didier Boturyn, Eric Defrancq, Mathieu Surin, Julien De Winter, Pascal Gerbaux, Ivan Jabin, Cécile Moucheron
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 1758-1768 (2018)
Photoactive ruthenium-based complexes are actively studied for their biological applications as potential theragnostic agents against cancer. One major issue of these inorganic complexes is to penetrate inside cells in order to fulfil their function,
Externí odkaz:
https://doaj.org/article/ed82aefa2b9b4543a7d84e8115ecbfaa
Autor:
Zhao-Hui Jin, Atsushi B. Tsuji, Mélissa Degardin, Aya Sugyo, Yukie Yoshii, Kotaro Nagatsu, Ming-Rong Zhang, Yasuhisa Fujibayashi, Pascal Dumy, Didier Boturyn, Tatsuya Higashi
Publikováno v:
EJNMMI Research, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Background The present study proposed a new concept for targeted radionuclide therapy (TRT) to improve the intratumoral distribution of radioactivity using two different radiopharmaceuticals. We examined the efficacy of a combination of a te
Externí odkaz:
https://doaj.org/article/8b0bf5d5939249e6adaaf9de3eb3dad2
Publikováno v:
Organic Letters. 24:3407-3410
The chemical synthesis of disulfide-rich peptides such as toxins can be accomplished by using numerous orthogonal cysteine-protecting groups. Herein we report the use of the Hmb
Autor:
Tsuneo Saga, Pascal Dumy, Didier Boturyn, Ming-Rong Zhang, Yasuhisa Fujibayashi, Kazunori Kawamura, Tomoteru Yamasaki, Atsushi B. Tsuji, Aya Sugyo, Mélissa Degardin, Takako Furukawa, Zhao-Hui Jin
Supplementary Files contain (1) Supplementary Materials and Methods for �V�3 expression analysis, autoradiography and histological analysis, and hematology and hepatorenal function; (2) Supplementary Tables S1-S5; and (3) Supplementary Fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5617ca4c1cfbe974946733501a6115ac
https://doi.org/10.1158/1535-7163.22504255
https://doi.org/10.1158/1535-7163.22504255
Autor:
Tsuneo Saga, Pascal Dumy, Didier Boturyn, Ming-Rong Zhang, Yasuhisa Fujibayashi, Kazunori Kawamura, Tomoteru Yamasaki, Atsushi B. Tsuji, Aya Sugyo, Mélissa Degardin, Takako Furukawa, Zhao-Hui Jin
Figure S1ï€The treatment outcomes of radiotherapy with 37 MBq (1 nmol) of 64Cu-cyclam-RAFT-c(-RGDfK-)4; Figure S2ï€Toxicity studies in normal mice that were injected with 74 MBq of 64Cu-cyclam-RAFT-c(-RGDfK-)4; Figure S3ï€Preliminary s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2de10b558181714d86589896202c196c
https://doi.org/10.1158/1535-7163.22504261
https://doi.org/10.1158/1535-7163.22504261
Autor:
Tsuneo Saga, Pascal Dumy, Didier Boturyn, Ming-Rong Zhang, Yasuhisa Fujibayashi, Kazunori Kawamura, Tomoteru Yamasaki, Atsushi B. Tsuji, Aya Sugyo, Mélissa Degardin, Takako Furukawa, Zhao-Hui Jin
The files contain (1) Supplementary Materials and Methods for αVβ3 expression analysis, autoradiography and histological analysis, and hematology and hepatorenal function; (2) Supplementary Tables S1-S5; and (3) Supplementary Figures S1-S5. Tab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bb93823b13f95969e7238b35635bc46
https://doi.org/10.1158/1535-7163.22504252
https://doi.org/10.1158/1535-7163.22504252