Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Diddahally R Govindaraju"'
Autor:
Diddahally R Govindaraju
Publikováno v:
PLoS Biology, Vol 17, Iss 4, p e3000215 (2019)
Recognition and exploitation of hybrid vigor or heterosis among individual crosses of plants and animals has a long and distinguished history. Its manifestation is influenced by a combination of genetic, epigenetic, phenotypic, and environmental fact
Externí odkaz:
https://doaj.org/article/79761fbf0ba14cfbb23b2e6e44e56401
Autor:
Diddahally R. Govindaraju
Publikováno v:
Evolution: Education and Outreach, Vol 13, Iss 1, Pp 1-6 (2020)
Abstract Ken Burns, a well-known documentarian has produced a film titled, “The Gene: An Intimate History” based on Siddhartha Mukherjee’s book by the same name. The film focuses sharply on the history of genetics, the science of inheritance an
Externí odkaz:
https://doaj.org/article/356e1a7cc57f4982928acea5236b2d45
Publikováno v:
Trends in Genetics
Trends in Genetics, Elsevier, 2020, 36, pp.395-402. ⟨10.1016/j.tig.2020.02.004⟩
Trends in Genetics, Elsevier, 2020, 36, pp.395-402. ⟨10.1016/j.tig.2020.02.004⟩
Aging entails an irreversible deceleration of physiological processes, altered metabolic activities, and a decline of the integrity of tissues, organs, and organ systems. The accumulation of alterations in the genetic and epigenetic spaces has been p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6df2d71325d6fe80d160b70b7d4f4912
https://doi.org/10.1016/j.tig.2020.02.004
https://doi.org/10.1016/j.tig.2020.02.004
Publikováno v:
Human genetics. 139(3)
Mutation accumulation has been proposed as a cause of senescence. During this process, age-related genetic and epigenetic mutations steadily accumulate. Cascading deleterious effects of mutations might initiate a steady “accumulation of deficits”
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24c211e36d162e238911e6feba4db38e
https://pubmed.ncbi.nlm.nih.gov/31713020
https://pubmed.ncbi.nlm.nih.gov/31713020
Publikováno v:
Applied and Translational Genomics, Vol 7, Iss C, Pp 40-44 (2015)
Applied & Translational Genomics
Applied & Translational Genomics
All biological variation is hierarchically organized dynamic network system of genomic components, organelles, cells, tissues, organs, individuals, families, populations and metapopulations. Individuals are axial in this hierarchy, as they represent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::403d0a4559f8f75ffa677f15c3ff2da6
Publikováno v:
Applied and Translational Genomics, Vol 4, Iss C, Pp 23-32 (2015)
Applied & Translational Genomics
Applied & Translational Genomics
Longevity as a complex life-history trait shares an ontogenetic relationship with other quantitative traits and varies among individuals, families and populations. Heritability estimates of longevity suggest that about a third of the phenotypic varia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8410a3c1ffe5b105666cc5ef075c1b34
http://www.sciencedirect.com/science/article/pii/S2212066115000022
http://www.sciencedirect.com/science/article/pii/S2212066115000022
Autor:
Lital Sharvit, Gil Atzmon, Sandy Ott, Danielle Gutman, Temuri Budagov, Pinchas Cohen, Robert C. Kaplan, Alexander P. Reiner, Bing Liu, Danny Ben-Avraham, Delphine Fradin, Peter Durda, Pierre Bougnères, Alan R. Shuldiner, Nir Barzilai, Diddahally R. Govindaraju
Publikováno v:
Science Advances
Science Advances, 2017, 3 (6), pp.e1602025. ⟨10.1126/sciadv.1602025⟩
Science Advances, American Association for the Advancement of Science (AAAS), 2017, 3 (6), pp.e1602025. ⟨10.1126/sciadv.1602025⟩
Science Advances, 2017, 3 (6), pp.e1602025. ⟨10.1126/sciadv.1602025⟩
Science Advances, American Association for the Advancement of Science (AAAS), 2017, 3 (6), pp.e1602025. ⟨10.1126/sciadv.1602025⟩
The d3-GHR genetic variant polymorphism modulates GH responsiveness throughout life span and positively affects male longevity.
Although both growth hormone (GH) and insulin-like growth factor 1 (IGF-1) signaling were shown to regulate life span
Although both growth hormone (GH) and insulin-like growth factor 1 (IGF-1) signaling were shown to regulate life span
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ad02c6e99b0657ef8efed873f21b237
https://www.hal.inserm.fr/inserm-02320509
https://www.hal.inserm.fr/inserm-02320509
Autor:
Diddahally R. Govindaraju
Publikováno v:
Evolution: Education and Outreach. 9
Mukherjee, S. The Gene: An intimate history.Scribner, NY.594 pages; ISBN: 978-1-4767-330-0; Price: $20.00.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7270e1104d8367c8c08a3ab56af45784
https://doi.org/10.1186/s12052-016-0063-x
https://doi.org/10.1186/s12052-016-0063-x
Publikováno v:
Trends in Cell Biology
Trends in Cell Biology, Elsevier, 2017, 27 (4), pp.299-310. ⟨10.1016/j.tcb.2016.11.006⟩
Trends in Cell Biology, Elsevier, 2017, 27 (4), pp.299-310. ⟨10.1016/j.tcb.2016.11.006⟩
International audience; Aging involves a progressive decline of metabolic function and an increased incidence of late-onset degenerative disorders and cancer. To a large extent, these processes are influenced by alterations affecting the integrity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edd03668138dd8b4af6f5bea2fcd6c7e
https://pubmed.ncbi.nlm.nih.gov/27939088
https://pubmed.ncbi.nlm.nih.gov/27939088