Výsledky vyhledávání - "Dicloxacillin/pharmacology"

Molecular mechanisms of thioridazine resistance in Staphylococcus aureus

Autor: Mette Thorsing, Sabrina Prehn Lauritzen, Lars Christian Lund, Claes Søndergaard Wassmann, Janne Kudsk Klitgaard, Birgitte H. Kallipolitis, Hans Jørn Kolmos

Publikováno v: PLoS ONE
PLoS ONE, Vol 13, Iss 8, p e0201767 (2018)
Wassmann, C S, Lund, L C, Thorsing, M, Prehn Lauritzen, S, Kolmos, H J, Kallipolitis, B H & Klitgaard, J K 2018, ' Molecular mechanisms of thioridazine resistance in Staphylococcus aureus ', P L o S One, vol. 13, no. 8, e0201767, pp. 1-17 . https://doi.org/10.1371/journal.pone.0201767

Staphylococcus aureus has developed resistance towards the most commonly used anti-staphylococcal antibiotics. Therefore, there is an urgent need to find new treatment opportunities. A new approach relies on the use of helper compounds, which are abl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::475ac340bc45a26e8fbc952d88204ae9
http://europepmc.org/articles/PMC6082566

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Assessments of Thioridazine as a Helper Compound to Dicloxacillin against Methicillin-Resistant Staphylococcus aureus: In Vivo Trials in a Mouse Peritonitis Model

Autor: Peter B. Licht, Michael Stenger, Peter Bollen, Kristoffer Hendel, Hans Jørn Kolmos, Janne Kudsk Klitgaard

Publikováno v: PLoS ONE
Stenger, M, Hendel, K, Bollen, P, Licht, P B, Kolmos, H J & Klitgaard, J K 2015, ' Assessments of Thioridazine as a Helper Compound to Dicloxacillin against Methicillin-Resistant Staphylococcus aureus : In Vivo Trials in a Mouse Peritonitis Model ', P L o S One, vol. 10, no. 8, e0135571 . https://doi.org/10.1371/journal.pone.0135571
PLoS ONE, Vol 10, Iss 8, p e0135571 (2015)

Introduction The rise in antimicrobial resistance is a major global concern and requires new treatment strategies. The use of helper compounds, such as thioridazine (TDZ), an antipsychotic drug, in combination with traditional antibiotics must be inv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0e469a89bbee157d4440c8261533e84
https://pubmed.ncbi.nlm.nih.gov/26267376

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Intra- and extracellular activities of dicloxacillin and linezolid against a clinical Staphylococcus aureus strain with a small-colony-variant phenotype in an in vitro model of THP-1 macrophages and an in vivo mouse peritonitis model

Autor: Sandberg, Anne, Lemaire, Sandrine, Van Bambeke, Françoise, Tulkens, Paul M., Hughes, Diarmaid, von Eiff, Christof, Frimodt-Møller, Niels

Publikováno v: Antimicrobial Agents and Chemotherapy, Vol. 55, no. 4, p. 1443-1452 (2011)
Antimicrobial Agents and Chemotherapy

The small-colony-variant (SCV) phenotype of Staphylococcus aureus has been associated with difficult-to-treat infections, reduced antimicrobial susceptibility, and intracellular persistence. This study represents a detailed intra- and extracellular i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f006ae1abdfa74fb4e9696e38cac930c
https://hdl.handle.net/2078.1/105994

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Change in International Normalized Ratio Among Patients Treated With Dicloxacillin and Vitamin K Antagonists

Autor: Per Damkier, Kenneth Grønkjær Madsen, Maja Hellfritzsch, Anton Pottegård, Daniel Pilsgaard Henriksen, Tore Bjerregaard Stage

Publikováno v: Pottegård, A, Henriksen, D P, Madsen, K G, Simonsen, M H, Damkier, P & Stage, T B 2015, ' Change in International Normalized Ratio Among Patients Treated With Dicloxacillin and Vitamin K Antagonists ', JAMA-Journal of the American Medical Association, vol. 314, no. 3, pp. 296-297 . https://doi.org/10.1001/jama.2015.6669

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a1fe7bef1d28a3977e6fdea0b5e55cc
https://doi.org/10.1001/jama.2015.6669

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