Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Dicky G. Abraham"'
Autor:
Tapas K. Makar, Vinayak S. Gokhale, Arthur J.L. Cooper, Dicky G. Abraham, Karin Rimpel-Lamhaouar
Publikováno v:
Journal of Neurochemistry. 65:287-291
The specific activities of superoxide dismutase, catalase, and glutathione S-transferase (μ subtype) were significantly lower in the brains of mice with type II diabetes than in the brains of control mice. On the other hand, the specific activity of
Autor:
Qinjian Zhao, Clinton S. Potter, Robert D. Sitrin, Jaime Sworen, Victoria Towne, Bridget Carragher, Dicky G. Abraham, Michael W. Washabaugh, Paul Duncan, Gabriel C. Lander
Publikováno v:
Human vaccinesimmunotherapeutics. 10(3)
Cryo-transmission electron microscopy (cryoTEM) is a powerful characterization method for assessing the structural properties of biopharmaceutical nanoparticles, including Virus Like Particle-based vaccines. We demonstrate the method using the Human
Publikováno v:
Journal of Biological Chemistry. 272:29380-29389
This study examines the interactions of alphavbeta3 and alpha5beta1 in the regulation of cell migration. Human embryonic kidney (HEK) 293 cells that express alpha5beta1 endogenously were transfected with alphavbeta3 and beta3 mutants, and their attac
Autor:
Elka M. Nutt, Dicky G. Abraham, Le T. Duong, Rodney A. Bednar, Robert J. Gould, Bohumil Bednar
Publikováno v:
Molecular Pharmacology. 52:227-236
The platelet-specific integrin alphaIIb beta3 achieves a high affinity binding state in response to extracellular agonists such as thrombin, ADP, or collagen. During this activation, the receptor undergoes a number of conformational changes. To chara
Autor:
Arthur J.L. Cooper, Dicky G. Abraham
Publikováno v:
Archives of Biochemistry and Biophysics. 335:311-320
An α-keto acid-dependent cysteine S -conjugate β-lyase of rat kidney was identified as cytosolic glutamine transaminase K by Stevens et al. ( J. Biol. Chem. 261, 15529–15537, 1986). Subsequently, a rat kidney protein with both glutamine transamin
Autor:
Qinjian Zhao, Victoria Towne, Dicky G. Abraham, Robert D. Sitrin, Ronald C. Kennedy, Yang Wang
Publikováno v:
Biochemical and biophysical research communications. 408(3)
The Hepatitis B virus major surface antigen (HBsAg) is a cysteine-rich, membrane-bound protein which self-assembles into 22-nm spherical virus-like particles (VLPs). While this VLP based human vaccine has been demonstrated to be safe and efficacious
Autor:
Arthur J.L. Cooper, Dicky G. Abraham
Publikováno v:
Analytical Biochemistry. 197:421-427
An activity stain to detect glutamine transaminase K subjected to nondenaturing polyacrylamide gel electrophoresis (ND-PAGE) was developed. The gel is incubated with a reaction mixture containing L-phenyl-alanine, alpha-keto-gamma-methiolbutyrate (al
Publikováno v:
The Journal of biological chemistry. 270(1)
A cytosolic high M(r) cysteine-S-conjugate beta-lyase (apparent M(r) of approximately 330,000) has been partially purified from rat kidneys. The high M(r) lyase is also present in the mitochondria. The purified enzyme contains at least two proteins w
Publikováno v:
Journal of neurochemistry. 61(5)
Certain halogenated hydrocarbons, e.g., dichloroacetylene, are nephrotoxic to experimental animals and neurotoxic to humans; cysteine-S-conjugate beta-lyases may play a role in the nephrotoxicity. We now show that with dichlorovinylcysteine as substr