Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Dickson W L Wong"'
Autor:
Wai Han Yiu, Dickson W L Wong, Loretta Y Y Chan, Joseph C K Leung, Kwok Wah Chan, Hui Yao Lan, Kar Neng Lai, Sydney C W Tang
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88894 (2014)
Tissue kallikrein (KLK1) expression is up-regulated in human diabetic kidney tissue and induced by high glucose (HG) in human proximal tubular epithelial cells (PTEC). Since the kallikrein-kinin system (KKS) has been linked to cellular inflammatory p
Externí odkaz:
https://doaj.org/article/461f80e8003f413c9fc02858f4d40d16
Autor:
Hao Jia Wu, Wai Han Yiu, Rui Xi Li, Dickson W L Wong, Joseph C K Leung, Loretta Y Y Chan, Yuelin Zhang, Qizhou Lian, Miao Lin, Hung Fat Tse, Kar Neng Lai, Sydney C W Tang
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90883 (2014)
Bone marrow-derived mesenchymal stem cells (BM-MSCs) have recently shown promise as a therapeutic tool in various types of chronic kidney disease (CKD) models. However, the mechanism of action is incompletely understood. As renal prognosis in CKD is
Externí odkaz:
https://doaj.org/article/57419aea3cdf445aa9cabd84538a4876
Autor:
Patrick Droste, Dickson W. L. Wong, Mathias Hohl, Saskia von Stillfried, Barbara M. Klinkhammer, Peter Boor
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Background Heart diseases are among the leading causes of death worldwide, many of which lead to pathological cardiomyocyte hypertrophy and capillary rarefaction in both patients and animal models, the quantification of which is both technic
Externí odkaz:
https://doaj.org/article/12557f4a72d640e197d70545c78d9a78
Autor:
Christian Hemmers, Corinna Schulte, Julia Wollenhaupt, Dickson W. L. Wong, Eva Harlacher, Setareh Orth-Alampour, Barbara Mara Klinkhammer, Stephan H. Schirmer, Michael Böhm, Nikolaus Marx, Thimoteus Speer, Peter Boor, Joachim Jankowski, Heidi Noels
Publikováno v:
Biomedicines; Volume 10; Issue 2; Pages: 420
Biomedicines 10(2), 420 (2022). doi:10.3390/biomedicines10020420 special issue: "Special Issue "Acute Kidney Injury to Chronic Kidney Disease: Pathophysiology and Therapy Targets" / Special Issue Editors: Dr. Yu-Wei Fang, Guest Editor; Dr. Vin-Cent Wu, Guest Editor; Dr. Javier A. Neyra, Guest Editor"
Biomedicines, 10(2):420. MDPI AG
Biomedicines 10(2), 420 (2022). doi:10.3390/biomedicines10020420 special issue: "Special Issue "Acute Kidney Injury to Chronic Kidney Disease: Pathophysiology and Therapy Targets" / Special Issue Editors: Dr. Yu-Wei Fang, Guest Editor; Dr. Vin-Cent Wu, Guest Editor; Dr. Javier A. Neyra, Guest Editor"
Biomedicines, 10(2):420. MDPI AG
Biomedicines 10(2), 420 (2022). doi:10.3390/biomedicines10020420 special issue: "Special Issue "Acute Kidney Injury to Chronic Kidney Disease: Pathophysiology and Therapy Targets" / Special Issue Editors: Dr. Yu-Wei Fang, Guest Editor; Dr. Vin-Cent W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6bb512f5858bcba89962735cac74b7d
Autor:
Gary C. W. Chan, Wai Han Yiu, Hao Jia Wu, Dickson W. L. Wong, Miao Lin, Xiao Ru Huang, Hui Yao Lan, Sydney C. W. Tang
Publikováno v:
Mediators of Inflammation, Vol 2015 (2015)
To expand the armamentarium of treatment for chronic kidney disease (CKD), we explored the utility of boosting endogenously synthesized N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP), which is augmented by inhibition of the angiotensin converting en
Externí odkaz:
https://doaj.org/article/beaf275db73d4efba7ef1f4d6cdb73de
Autor:
Christine Joseph, Eva Maria Berghausen, Arnica Behringer, Bernhard Rauch, Henrik ten Freyhaus, Leoni Luisa Gnatzy-Feik, Max Krause, Dickson W L Wong, Peter Boor, Stephan Baldus, Marius Vantler, Stephan Rosenkranz
Publikováno v:
Cardiovascular research. 118(16)
Aims Pulmonary arterial hypertension (PAH) is a devastating disease with limited therapeutic options. Vascular remodelling of pulmonary arteries, characterized by increased proliferation and migration of pulmonary arterial smooth muscle cells (PASMCs
Autor:
Makoto Mark Taketo, Kar Neng Lai, Wai Han Yiu, Sarah W.Y. Lok, Sydney C.W. Tang, Peter Igarashi, Loretta Y.Y. Chan, Dickson W. L. Wong, Bin Li, Joseph Leung, Ye Li, Kam Wa Chan
Publikováno v:
Kidney International. 93:1367-1383
Imbalance of Wnt/β-catenin signaling in renal cells is associated with renal dysfunction, yet the precise mechanism is poorly understood. Previously we observed activated Wnt/β-catenin signaling in renal tubules during proteinuric nephropathy with
Autor:
Wuding Zhou, Kam Wa Chan, Sydney C.W. Tang, Kar Neng Lai, Wai Han Yiu, Rui Xi Li, Joseph Leung, Dickson W. L. Wong, Loretta Y.Y. Chan, Haojia Wu, Steven H. Sacks
Publikováno v:
Nephrology Dialysis Transplantation. 33:1323-1332
Background Complement C5 mediates pro-inflammatory responses in many immune-related renal diseases. Given that the C5a level is elevated in diabetes, we investigated whether activation of C5a/C5aR signalling plays a pathogenic role in diabetic nephro
Autor:
Yuelin Zhang, Loretta Y.Y. Chan, Sydney C.W. Tang, Hung-Fat Tse, Wai Han Yiu, Kar Neng Lai, Haojia Wu, Rui Xi Li, Qizhou Lian, Joseph Leung, Dickson W. L. Wong
Publikováno v:
Oncotarget
Human induced pluripotent stem cell-derived mesenchymal stem cells (iPS-MSCs) are emerging as attractive options for use in cell replacement therapy, but their effect in kidney diseases remains unknown. Here, we showed that intravenous injection of i
Autor:
Dickson W. L. Wong, Wai Han Yiu, Kar Neng Lai, Loretta Y.Y. Chan, Hui Y. Lan, Irene Yam, Rui Xi Li, Joseph Leung, Sydney C.W. Tang, Haojia Wu
Publikováno v:
Kidney International. 89:386-398
Kallistatin is a serine protease inhibitor with anti-inflammatory, anti-angiogenic, and anti-oxidative properties. Since oxidative stress plays a critical role in the pathogenesis of diabetic nephropathy, we studied the effect and mechanisms of actio