Zobrazeno 1 - 10
of 781
pro vyhledávání: '"Dickkopf"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Therapeutic antibodies (Abs) have been anticipated as promising alternatives to conventional treatments such as topical minoxidil and oral finasteride for androgenetic alopecia (AGA). Due to the high molecular weight of typical Abs, the half-life of
Externí odkaz:
https://doaj.org/article/bba5365674bc4ec99d89fa1a6ba7d62f
Autor:
Jingyi Wang, Qianying Li, Faya Liang, Xin Du, Pan Song, Taowei Wu, Renhui Chen, Xiaorong Lin, Qinglian Liu, Hai Hu, Ping Han, Xiaoming Huang
Publikováno v:
MedComm, Vol 5, Iss 4, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/87317a69074d411084db43820579371e
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionWnt-signaling is a key regulator of stem cell homeostasis, extensively studied in the intestinal crypt and other metazoan tissues. Yet, there is hardly any data available on the presence of Wnt-signaling components in the adult enteric ne
Externí odkaz:
https://doaj.org/article/75cf058f1d70402098f862fafc01edde
Autor:
Jung-Won Choi, Seung Eun Jung, Jung Hwa Kang, Sung Hwan Hwang, Sang Woo Kim, Ki-Chul Hwang, Seahyoung Lee
Publikováno v:
Journal of King Saud University: Science, Vol 35, Iss 5, Pp 102717- (2023)
Recently, we have established a method for culturing NK cell-enriched lymphocytes (NKELs) with high anti-cancer activity. These NKELs are found to be highly cytotoxic against various types of cancer cells, and even the extracellular vesicles derived
Externí odkaz:
https://doaj.org/article/acc6ccc898c944889dc9b4d23e762e80
Publikováno v:
Clinical, Cosmetic and Investigational Dentistry, Vol Volume 14, Pp 191-198 (2022)
Ehab Azab,1 Alaa Attia,1,2 Wael Yaghmoor,1 Salwa Aldahlawi,1 Abdel-Rahman Youssef1,3 1Department of Basic and Clinical Oral Sciences, Faculty of Dentistry, Umm Al-Qura University, Makkah, Saudi Arabia; 2Department of Oral Medicine and Periodontology,
Externí odkaz:
https://doaj.org/article/3636ab3e260e4ea59d88ddd796013150
Publikováno v:
BMC Research Notes, Vol 15, Iss 1, Pp 1-8 (2022)
Abstract Objective The detection and monitoring of DNA methylation status in circulating tumor cell DNA (ctDNA) provides critical insights into cancer diagnosis and progression. The methylation status of the Dickkopf-related protein 3 (DKK3) promoter
Externí odkaz:
https://doaj.org/article/cb696a0d271440079a650fda97afdd26
Publikováno v:
Cells, Vol 13, Iss 1, p 75 (2023)
The human Dickkopf (DKK) family includes four main secreted proteins, DKK-1, DKK-2, DKK-3, and DKK-4, as well as the DKK-3 related protein soggy (Sgy-1 or DKKL1). These glycoproteins play crucial roles in various biological processes, and especially
Externí odkaz:
https://doaj.org/article/cd0871806e2444fcae8791151bfd05aa
Autor:
Wenjun Ren, Yongwu Li, Xi Chen, Sheng Hu, Wanli Cheng, Yu Cao, Jingcheng Gao, Xia Chen, Da Xiong, Hongrong Li, Ping Wang
Publikováno v:
IET Systems Biology, Vol 16, Iss 2, Pp 43-58 (2022)
Abstract RYR2 mutation is clinically frequent in non‐small cell lung cancer (NSCLC) with its function being elusive. We downloaded lung squamous cell carcinoma and lung adenocarcinoma samples from the TCGA database, split the samples into RYR2 muta
Externí odkaz:
https://doaj.org/article/6ffd0360cb784158bbe0d9da35ff56a0
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundThe canonical Wnt inhibitor Dickkopf-1 (Dkk-1) has the capacity to modulate homeostasis between canonical and non-canonical Wnt pathways and also signal independently of Wnt. The specific effects of Dkk-1 activity on tumor physiology are th
Externí odkaz:
https://doaj.org/article/1d521291e12940efb1e800185d427a7b
Autor:
Dunja Mudri, Tomislav Kizivat, Martina Smolić, Ivica Mihaljević, Robert Smolić, Nikola Raguž Lučić, Ines Bilić-Ćurčić
Publikováno v:
Acta Clinica Croatica, Vol 61., Iss 3, Pp 496-504 (2022)
Graves’ disease is an autoimmune disease characterized by excessive thyroid hormone production. One of the consequences of that state can be a decrease in bone mineral density (BMD). Graves’ disease is often treated with antithyroid drugs (ATD)
Externí odkaz:
https://doaj.org/article/461073e6c03e40cc9df5783e3ca1850f