Toxicity Induced by Cytokines, Glucose, and Lipids Increase Apoptosis and Hamper Insulin Secretion in the 1.1E7 Beta Cell-Line

Autor: Aranzazu Quiroga-de-Castro, Alfonso M. Lechuga-Sancho, Antonia Diaz-Ganete, Carmen Segundo, Rosa M. Mateos, Francisco Medina

Publikováno v: Int. J. Mol. Sci. 2021, 22(5), 2559
International Journal of Molecular Sciences
RODIN. Repositorio de Objetos de Docencia e Investigación de la Universidad de Cádiz
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International Journal of Molecular Sciences, Vol 22, Iss 2559, p 2559 (2021)
RODIN: Repositorio de Objetos de Docencia e Investigación de la Universidad de Cádiz
Universidad de Cádiz
Volume 22
Issue 5

Basic research on types 1 and 2 diabetes mellitus require early stage studies using beta cells or cell lines, ideally of human origin and with preserved insulin secretion in response to glucose. The 1.1E7 cells are a hybrid cell line resulting from t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ddfe9c51071ebc35365b1d04af8c577
http://hdl.handle.net/10498/24711

Ghrelin’s Effects on Proinflammatory Cytokine Mediated Apoptosis and Their Impact on β-Cell Functionality.

Autor: Diaz-Ganete, Antonia¹ tonydiazganete@gmail.com, Baena-Nieto, Gloria^1,2 gbncucha@hotmail.com, Lomas-Romero, Isabel M.^1,3 isabelmarialomasromero@gmail.com, Lopez-Acosta, Jose Francisco^1,4 jf_lopez_a@hotmail.com, Cozar-Castellano, Irene⁴ cozarirene@gmail.com, Medina, Francisco^1,5 fmedinaprieto@gmail.com, Segundo, Carmen^1,5 csegundoiglesias@gmail.com, Lechuga-Sancho, Alfonso M.^1,6 alfonso.lechuga@uca.es

Publikováno v: International Journal of Endocrinology. 7/16/2015, Vol. 2015, p1-11. 11p.