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Multi-omics after O-GlcNAc alteration identified cellular processes promoting aneuploidy after loss of O-GlcNAc transferase.

Autor: Boyd SS; Department of Biostatistics and Data Science, University of Kansas Medical Center, Kansas City, KS, USA., Robarts DR; Department of Pharmacology, Toxicology and Therapeutics, Kansas City, KS, USA., Nguyen K; Department of Biochemistry, University of Kansas Medical Center, Kansas City, KS, USA., Villar M; Department of Biochemistry, University of Kansas Medical Center, Kansas City, KS, USA., Alghusen IM; Department of Biochemistry, University of Kansas Medical Center, Kansas City, KS, USA., Kotulkar M; Department of Pharmacology, Toxicology and Therapeutics, Kansas City, KS, USA., Denson A; Department of Biochemistry, University of Kansas Medical Center, Kansas City, KS, USA., Fedosyuk H; Department of Biochemistry, University of Kansas Medical Center, Kansas City, KS, USA., Whelan SA; Department of Chemistry, Boston University, Boston, MA, USA; Precision Biomarker Laboratories, Cedars-Sinai Medical Center, Beverly Hills, CA, USA., Lee NCY; Department of Chemistry, Boston University, Boston, MA, USA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Hanover J; Laboratory of Cell Biochemistry and Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA., Dias WB; Federal University of Rio De Janeiro, Rio De Janeiro, Brazil., Tan EP; Department of Biochemistry, University of Kansas Medical Center, Kansas City, KS, USA; Department of Chemistry, Neurodegeneration New Medicines Center, and the Skaggs Institute of Chemical Biology, The Scripps Research Institute, La Jolla, CA, USA., McGreal SR; Department of Pharmacology, Toxicology and Therapeutics, Kansas City, KS, USA; XenoTech, A BioIVT Company, Kansas City, KS, USA., Artigues A; Department of Biochemistry, University of Kansas Medical Center, Kansas City, KS, USA., Swerdlow RH; Department of Biochemistry, University of Kansas Medical Center, Kansas City, KS, USA; Department of Neurology, University of Kansas Medical Center, Kansas City, KS, USA; University of Kansas Alzheimer's Disease Research Center, KS, USA., Thompson JA; Department of Biostatistics and Data Science, University of Kansas Medical Center, Kansas City, KS, USA; University of Kansas Cancer Center, Kansas City, KS, USA., Apte U; Department of Pharmacology, Toxicology and Therapeutics, Kansas City, KS, USA., Slawson C; Department of Biochemistry, University of Kansas Medical Center, Kansas City, KS, USA; University of Kansas Alzheimer's Disease Research Center, KS, USA; University of Kansas Cancer Center, Kansas City, KS, USA. Electronic address: cslawson@kumc.edu.

Publikováno v: Molecular metabolism [Mol Metab] 2024 Oct 29; Vol. 90, pp. 102060. Date of Electronic Publication: 2024 Oct 29.

Multi-Omics after O-GlcNAc Alteration Identifies Cellular Processes Working Synergistically to Promote Aneuploidy.

Autor: Boyd SS, Robarts DR, Nguyen K, Villar M, Alghusen I, Kotulkar M, Denson A, Fedosyuk H, Whelan SA, Lee NCY, Hanover J, Dias WB, Tan EP, McGreal SR, Artigues A, Swerdlow RH, Thompson JA, Apte U, Slawson C

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Apr 16. Date of Electronic Publication: 2024 Apr 16.

O-Linked GlcNAcylation mediates the inhibition of proximal tubule (Na ⁺ +K ⁺ )ATPase activity in the early stage of diabetes mellitus.

Autor: Silva-Aguiar RP; Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil., Teixeira DE; Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil., Peres RAS; Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil., Alves SAS; Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil., Novaes-Fernandes C; Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil., Dias WB; Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil., Pinheiro AAS; Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil; Rio de Janeiro Innovation Network in Nanosystems for Health - NanoSAUDE/FAPERJ, Rio de Janeiro, Brazil., Peruchetti DB; Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil; Departamento de Fisiologia e Biofísica, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil., Caruso-Neves C; Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil; Rio de Janeiro Innovation Network in Nanosystems for Health - NanoSAUDE/FAPERJ, Rio de Janeiro, Brazil; Instituto Nacional de Ciência e Tecnologia em Medicina Regenerativa, INCT-Regenera, Conselho Nacional de Desenvolvimento Científico e Tecnológico/MCTIC, Rio de Janeiro, Brazil. Electronic address: caruso@biof.ufrj.br.

Publikováno v: Biochimica et biophysica acta. General subjects [Biochim Biophys Acta Gen Subj] 2023 Nov; Vol. 1867 (11), pp. 130466. Date of Electronic Publication: 2023 Sep 22.