Pseudouridine synthase 1 promotes hepatocellular carcinoma through mRNA pseudouridylation to enhance the translation of oncogenic mRNAs.

Autor: Hu YX; Biotherapy Center, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, PR China., Diao LT; Biotherapy Center, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, PR China., Hou YR; Biotherapy Center, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, PR China., Lv G; Guangdong Key Laboratory of Liver Disease Research, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, PR China., Tao S; Biotherapy Center, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, PR China., Xu WY; Biotherapy Center, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, PR China., Xie SJ; Institute of Vaccine, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, PR China., Ren YH; Biotherapy Center, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, PR China., Xiao ZD; Biotherapy Center, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, PR China.

Publikováno v: Hepatology (Baltimore, Md.) [Hepatology] 2024 Nov 01; Vol. 80 (5), pp. 1058-1073. Date of Electronic Publication: 2023 Nov 28.

RNA-binding protein CCDC137 activates AKT signaling and promotes hepatocellular carcinoma through a novel non-canonical role of DGCR8 in mRNA localization.

Autor: Tao S; Biotherapy Center, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510630, P.R. China.; Present address: Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, P.R. China., Xie SJ; Institute of Vaccine, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510630, P.R. China., Diao LT; Biotherapy Center, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510630, P.R. China., Lv G; Guangdong Key Laboratory of Liver Disease Research, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510630, P.R. China., Hou YR; Biotherapy Center, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510630, P.R. China., Hu YX; Biotherapy Center, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510630, P.R. China., Xu WY; Biotherapy Center, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510630, P.R. China., Du B; Department of Pathology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, 200092, P.R. China. dubin@tongji.edu.cn., Xiao ZD; Biotherapy Center, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510630, P.R. China. xiaozhd@mail2.sysu.edu.cn.

Publikováno v: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2023 Aug 05; Vol. 42 (1), pp. 194. Date of Electronic Publication: 2023 Aug 05.

Characterization of Long Non-coding RNAs Modified by m ⁶ A RNA Methylation in Skeletal Myogenesis.

Autor: Xie SJ; Vaccine Research Institute of Sun Yat-sen University, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.; Biotherapy Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China., Tao S; Biotherapy Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China., Diao LT; Biotherapy Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China., Li PL; Biotherapy Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China., Chen WC; Biotherapy Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China., Zhou ZG; Department of Orthopedics, First Affiliated Hospital, Jinan University, Guangzhou, China., Hu YX; Biotherapy Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China., Hou YR; Biotherapy Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China., Lei H; Biotherapy Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China., Xu WY; Biotherapy Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China., Chen WJ; Biotherapy Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China., Peng YW; Biotherapy Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China., Zhang Q; Vaccine Research Institute of Sun Yat-sen University, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.; Biotherapy Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China., Xiao ZD; Biotherapy Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.

Publikováno v: Frontiers in cell and developmental biology [Front Cell Dev Biol] 2021 Oct 13; Vol. 9, pp. 762669. Date of Electronic Publication: 2021 Oct 13 (Print Publication: 2021).

mascRNA and its parent lncRNA MALAT1 promote proliferation and metastasis of hepatocellular carcinoma cells by activating ERK/MAPK signaling pathway.

Autor: Xie SJ; Vaccine Research Institute of Sun Yat-sen University, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, China., Diao LT; Biotherapy Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, China., Cai N; Vaccine Research Institute of Sun Yat-sen University, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, China., Zhang LT; Vaccine Research Institute of Sun Yat-sen University, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, China., Xiang S; Department of Hepatic Surgery and Liver Transplantation Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, China., Jia CC; Biotherapy Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, China., Qiu DB; Vaccine Research Institute of Sun Yat-sen University, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, China., Liu C; Biotherapy Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, China., Sun YJ; Biotherapy Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, China., Lei H; Biotherapy Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, China., Hou YR; Biotherapy Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, China., Tao S; Biotherapy Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, China., Hu YX; Biotherapy Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, China., Xiao ZD; Biotherapy Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, China. xiaozhd@mail2.sysu.edu.cn., Zhang Q; Vaccine Research Institute of Sun Yat-sen University, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, China. zhangq27@mail.sysu.edu.cn.; Biotherapy Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, China. zhangq27@mail.sysu.edu.cn.

Publikováno v: Cell death discovery [Cell Death Discov] 2021 May 17; Vol. 7 (1), pp. 110. Date of Electronic Publication: 2021 May 17.

N ⁶ -methyladenine demethylase ALKBH1 inhibits the differentiation of skeletal muscle.

Autor: Diao LT; Biotherapy Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, China. Electronic address: diaolt@mail2.sysu.edu.cn., Xie SJ; Biotherapy Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, China; Vaccine Research Institute of Sun Yat-sen University, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, China. Electronic address: xieshj5@mail.sysu.edu.cn., Yu PJ; Key Laboratory of Gene Engineering of the Ministry of Education, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, 510275, China. Electronic address: yupj3@mail2.sysu.edu.cn., Sun YJ; Biotherapy Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, China. Electronic address: 1614968131@qq.com., Yang F; Biotherapy Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, China. Electronic address: yangfanxiyi@qq.com., Tan YY; Key Laboratory of Gene Engineering of the Ministry of Education, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, 510275, China. Electronic address: yeyatam@hotmail.com., Tao S; Biotherapy Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, China. Electronic address: ts19940821@163.com., Hou YR; Biotherapy Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, China. Electronic address: houyarui2018@163.com., Zheng LL; Key Laboratory of Gene Engineering of the Ministry of Education, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, 510275, China. Electronic address: zhengll33@mail.sysu.edu.cn., Xiao ZD; Biotherapy Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, China. Electronic address: xiaozhd@mail2.sysu.edu.cn., Zhang Q; Biotherapy Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, China; Vaccine Research Institute of Sun Yat-sen University, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, China. Electronic address: zhangq27@mail.sysu.edu.cn.

Publikováno v: Experimental cell research [Exp Cell Res] 2021 Mar 15; Vol. 400 (2), pp. 112492. Date of Electronic Publication: 2021 Jan 30.