Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Dianze Song"'
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract Background Activation of the NLRP3 inflammasome is critical in the inflammatory response to gout. Potassium ion (K+) efflux mediated by the TWIK2 channel is an important upstream mechanism for NLRP3 inflammasome activation. Therefore, the TW
Externí odkaz:
https://doaj.org/article/81865ab612744afb8397769e76bd6588
Publikováno v:
Molecular Medicine, Vol 29, Iss 1, Pp 1-19 (2023)
Abstract Background Maresin1 (MaR1) is a potent lipid mediator that exhibits significant anti-inflammatory activity in the context of several inflammatory diseases. A previous study reported that MaR1 could suppress MSU crystal-induced peritonitis in
Externí odkaz:
https://doaj.org/article/9b28b92c57a94cb7abac0d126c87b4ee
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-23 (2023)
Abstract Background Previous studies have revealed that Sirt3 deficiency is associated with several inflammatory responses. The purpose of this study is to investigate the role and potential molecular mechanisms of Sirt3 in the inflammation induced b
Externí odkaz:
https://doaj.org/article/75a5d0d9ed5e4edeb4ed0c38d413f7bf
Publikováno v:
Oxidative Medicine and Cellular Longevity. 2022:1-22
Excessive generation of reactive oxygen species (ROS) has great impacts on MSU crystal-induced inflammation. Drp1-dependent mitochondrial fission is closely associated with mitochondrial ROS levels. However, whether Drp1 signaling contributes to MSU