Výsledky vyhledávání - "Dianxiong Zou"

Akademický článek

Behavioral Effects of a Chemorepellent Receptor Knockout Mutation in Tetrahymena thermophila

Publikováno v: mSphere, Vol 2, Iss 4 (2017)

ABSTRACT A conditioned supernatant from Tetrahymena thermophila contains a powerful chemorepellent for wild-type cells, and a gene called G37 is required for this response. This is the first genomic identification of a chemorepellent receptor in any

Externí odkaz: https://doaj.org/article/d2012bd2814d4048834a9806a62b5789

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Nanocurcumin combined with insulin alleviates diabetic kidney disease through P38/P53 signaling axis

Autor: Raghu, Ganugula, Nikhil K, Nuthalapati, Subhash, Dwivedi, Dianxiong, Zou, Meenakshi, Arora, Richard, Friend, David, Sheikh-Hamad, Rita, Basu, M N V Ravi, Kumar

Publikováno v: Journal of Controlled Release. 353:621-633

Treatments for diabetic kidney disease (DKD) mainly focus on managing hyperglycemia and hypertension, but emerging evidence suggests that inflammation also plays a role in the pathogenesis of DKD. This 10-week study evaluated the efficacy of daily or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c4ee91196817b0a697449066a6bc951
https://doi.org/10.1016/j.jconrel.2022.12.012

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Nanoparticles that do not compete with endogenous ligands – Molecular characterization in vitro, acute safety in canine, and interspecies pharmacokinetics modeling to humans

Autor: Mokshada Kumar, Dhaval K. Shah, Raghu Ganugula, Meenakshi Arora, Erin M. Scott, Dianxiong Zou, M. N. V. Ravi Kumar

Publikováno v: J Control Release

A vast majority, if not all of the receptor-mediated drug delivery systems utilize nanoparticles that are conjugated to physiological mimic ligands, with testing restricted to in vitro and rodent models. In this report, we present for the first time,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6edac25a2d5f89254566aed86a6d45f8
https://doi.org/10.1016/j.jconrel.2021.02.009

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A highly potent lymphatic system–targeting nanoparticle cyclosporine prevents glomerulonephritis in mouse model of lupus

Autor: Sandeep K. Agarwal, Meenakshi Arora, Dianxiong Zou, Chandra Mohan, M. N. V. Ravi Kumar, Raghu Ganugula

Publikováno v: Science Advances

Orally delivered lymphatic system–specific nanoparticle cyclosporine is an effective way to treat lupus.
Cyclosporine A (CsA) is a powerful immunosuppressant, but it is an ineffective stand-alone treatment for systemic lupus erythematosus (SLE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::084ac8ac1d50a26cb793a434fa366010
http://europepmc.org/articles/PMC7292630

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Oral delivery of nanoparticle urolithin A normalizes cellular stress and improves survival in mouse model of cisplatin-induced AKI

Autor: Raghu Ganugula, M. N. V. Ravi Kumar, Mary B. Nabity, Dianxiong Zou, Meenakshi Arora, David Sheikh-Hamad

Publikováno v: American journal of physiology. Renal physiology. 317(5)

The popular anticancer drug cisplatin causes many adverse side effects, the most serious of which is acute kidney injury (AKI). Emerging evidence from laboratory and clinical studies suggests that the AKI pathogenesis involves oxidative stress pathwa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7e554868e3c556bf2af936a30aec1db
https://pubmed.ncbi.nlm.nih.gov/31532243

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Akademický článek

Oral delivery of nanoparticle urolithin A normalizes cellular stress and improves survival in mouse model of cisplatin-induced AKI.

Autor: Dianxiong Zou, Ganugula, Raghu, Arora, Meenakshi, Nabity, Mary B., Sheikh-Hamad, David, Kumar, M. N. V.Ravi

Publikováno v: American Journal of Physiology: Renal Physiology; Nov2019, Vol. 317 Issue 5, pF1255-F1264, 10p, 1 Chart, 5 Graphs

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