Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Dianqing Sun"'
Autor:
Mingming Zhang, Allan M. Prior, Marcus M. Maddox, Wan-Jou Shen, Kirk E. Hevener, David F. Bruhn, Robin B. Lee, Aman P. Singh, Justin Reinicke, Charles J. Simmons, Julian G. Hurdle, Richard E. Lee, Dianqing Sun
Publikováno v:
ACS Omega, Vol 3, Iss 12, Pp 18343-18360 (2018)
Externí odkaz:
https://doaj.org/article/27abe659138b4f32a2e630d0506d1f8f
Autor:
Abdrrahman Shemsu Surur, Dianqing Sun
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
The tale of abate in antibiotics continued defense mechanisms that chaperone the rise of drug-defying superbugs—on the other hand, the astray in antibacterial drug discovery and development. Our salvation lies in circumventing the genesis of resist
Externí odkaz:
https://doaj.org/article/60b8db11006542249639e853f6d642ce
Autor:
Dianqing Sun
Publikováno v:
Molecules, Vol 27, Iss 3, p 1012 (2022)
Macrocycles represent attractive candidates in organic synthesis and drug discovery. Since 2014, nineteen macrocyclic drugs, including three radiopharmaceuticals, have been approved by FDA for the treatment of bacterial and viral infections, cancer,
Externí odkaz:
https://doaj.org/article/c9e23fd9614345c48c378e244a05c19d
Autor:
Pamela K Garcia, Thirunavukkarasu Annamalai, Wenjie Wang, Raven S Bell, Duc Le, Paula Martin Pancorbo, Sabah Sikandar, Ahmed Seddek, Xufen Yu, Dianqing Sun, Anne-Catrin Uhlemann, Purushottam B Tiwari, Fenfei Leng, Yuk-Ching Tse-Dinh
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0207733 (2019)
We have previously reported the inhibition of bacterial topoisomerase I activity by a fluoroquinophenoxazine compound (FP-11g) with a 6-bipiperidinyl lipophilic side chain that exhibited promising antituberculosis activity (MIC = 2.5 μM against Myco
Externí odkaz:
https://doaj.org/article/d9bfda57d9f048fe980faa0d20768f76
Autor:
Xufen Yu, Dianqing Sun
Publikováno v:
Molecules, Vol 18, Iss 6, Pp 6230-6268 (2013)
Macrocyclic scaffolds are commonly found in bioactive natural products and pharmaceutical molecules. So far, a large number of macrocyclic natural products have been isolated and synthesized. The construction of macrocycles is generally considered as
Externí odkaz:
https://doaj.org/article/e6a4702d8ae94f33823d8c0dd85dd143
Publikováno v:
Molecules, Vol 23, Iss 6, p 1475 (2018)
Macrocyclic peptides are privileged scaffolds for drug development and constitute a significant portion of macrocyclic drugs on the market today in fields spanning from infectious disease to oncology. Developing orally bioavailable peptide-based drug
Externí odkaz:
https://doaj.org/article/308435390b77449f89fb0e1c50e0c21f
Autor:
Krissada Norseeda, Fahad Bin Aziz Pavel, Jacob T. Rutherford, Humna N. Meer, Chetna Dureja, Julian G. Hurdle, Kirk E. Hevener, Dianqing Sun
Publikováno v:
Bioorganic & Medicinal Chemistry. :117330
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec3c33e9836947bb1bafe7cf5cf96ee2
https://doi.org/10.1016/j.bmc.2023.117330
https://doi.org/10.1016/j.bmc.2023.117330
Publikováno v:
American Journal of Pharmaceutical Education. :100056
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebd5ea53b8b426cab1979430d4362b3d
https://doi.org/10.1016/j.ajpe.2023.100056
https://doi.org/10.1016/j.ajpe.2023.100056
Publikováno v:
Encyclopedia of Infection and Immunity ISBN: 9780323903035
Reference Module in Biomedical Sciences
Reference Module in Biomedical Sciences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b03d1e2480c61a20a404e9572a7accd
https://doi.org/10.1016/b978-0-12-818731-9.00144-0
https://doi.org/10.1016/b978-0-12-818731-9.00144-0
Autor:
Dianqing Sun, Julian G Hurdle, Ravi K. R. Marreddy, Kirk E. Hevener, Rebecca D Wahrmund, Jesse A. Jones, Allan M. Prior
Publikováno v:
ACS Chem Biol
Clostridioides difficile infection (CDI) is a leading cause of significant morbidity, mortality, and healthcare-related costs in the United States. After standard therapy, recurrence rates remain high, and multiple recurrences are not uncommon. Cause
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb17007256f17bacf15a7a58d4e436a3
https://doi.org/10.1021/acschembio.9b00293
https://doi.org/10.1021/acschembio.9b00293