Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Dianne M. Adams"'
Autor:
Xing Q. Pan, Werner Tjarks, Supriya Shukla, Rolf F. Barth, Robert J. Lee, Masaru Sekido, Dianne M. Adams, Huaqing Wang
Publikováno v:
Bioconjugate Chemistry. 13:435-442
Boron neutron capture therapy (BNCT) depends on the selective delivery of a sufficient number of (10)B atoms to tumor cells to sustain a lethal (10)B(n,alpha)(7)Li reaction. Expression of FR frequently is amplified among human tumors. The goal of the
Autor:
Joan H. Rotaru, Robert J. Lee, Masaru Sekido, Jennifer J. Sudimack, Dianne M. Adams, Rolf F. Barth, Junhua Yan, Supriya Shukla, Werner Tjarks
Publikováno v:
Pharmaceutical Research. 19:1502-1508
Purpose. This study was aimed at the in vitro evaluations of folate receptor (FR)-targeted liposomes as carriers for a lipophilic boron agent, K[nido-7-CH3(CH2)15-7,8-C2B9H11], in FR-overexpressing tumor cells for neutron capture therapy.
Autor:
Robert A. Fenstermaker, Jacek Capala, Rolf F. Barth, Michael J. Ciesielski, Dianne M. Adams, Weilian Yang, Renée Léveillé
Publikováno v:
Journal of Neuro-Oncology. 55:19-28
We have previously reported a method for labeling epidermal growth factor (EGF) with technetium-99m and have shown that 99mTc-EGF localized in EGF receptor (R) positive intracerebral C6EGFR rat gliomas following intratumoral (i.t.) injection of the r
Autor:
Alfred E. Staubus, Mao Zhi Zhang, Rolf F. Barth, Joseph H. Goodman, Carl P. Boesel, Chung Cheng Wang, Christopher R. Gibson, Reinhard A. Gahbauer, Weilian Yang, Brent J. Albertson, Nilendu Gupta, Melvin L. Moeschberger, Zhixian Gao, David E. Carpenter, Albert H. Soloway, Dianne M. Adams, Amy K. Ferketich, William F. Bauer
Publikováno v:
Neurosurgery. 47:608-622
OBJECTIVE The purpose of this study was to obtain tumor and normal brain tissue biodistribution data and pharmacokinetic profiles for sodium borocaptate (Na2B12H11SH) (BSH), a drug that has been used clinically in Europe and Japan for boron neutron c
Autor:
Jin-Cong Zhuo, Dianne M. Adams, Albert H. Soloway, Jianping Cai, Rolf F. Barth, Werner Tjarks, Weihua Ji
Publikováno v:
Journal of Medicinal Chemistry. 42:1282-1292
New boron-containing spermidine/spermine (SPD/SPM) analogues have been synthesized: N5-[4-(2-aminoethyl-o-carboranyl)butyl] and N5-{4-[(2,3-dihydroxypropyl)-o-carboranyl]butyl} SPD/SPM derivatives (ASPD-5, ASPM-5, DHSPD-5, and DHSPM-5) as well as N5-
Autor:
Iwona M. Wyzlic, Jianping Cai, Joya R. Hariharan, Krista Radcliffe, Dianne M. Adams, Rolf F. Barth, Albert H. Soloway
Publikováno v:
Journal of Medicinal Chemistry. 40:3887-3896
Three series of new boron-containing spermidine/spermine (SPD/SPM) analogues have been synthesized: N1- and N5-(4-carboranylbutyl) SPD/SPM derivatives (SPD-1, SPD-5, SPM-1, SPM-5); N1,N10-diethyl-N5-(4-carboranylbutyl)spermidine (DESPD-5), N1,N14-die
Autor:
Moïse Bendayan, Albert H. Soloway, Robert A. Fenstermaker, Jacek Capala, Dianne M. Adams, Michel Lauzon, Jorgen Carlsson, Rolf F. Barth
Publikováno v:
Bioconjugate Chemistry. 7:7-15
In order for boron neutron capture therapy (BNCT) to be successful, a large number (approximately 10(9)) of 10B atoms must be delivered to each cancer cell in order to sustain a lethal 10B(n, alpha)7Li reaction. The majority of high grade gliomas exp
Publikováno v:
Journal of Hematotherapy. 4:477-483
Boron neutron capture therapy (BNCT) is based on the nuclear reaction that occurs when boron-10, a stable isotope, is irradiated with low energy (< or = 0.025 eV) or thermal neutrons to yield alpha particles and recoiling lithium-7 nuclei. A major re
Autor:
Albert H. Soloway, Abul K. M. Anisuzzaman, Douglas J. Perkins, L. Liu, Dianne M. Adams, Rolf F. Barth, Werner Tjarks
Publikováno v:
ChemInform. 24
The following boron-containing nucleoside and glucose derivatives have been synthesized as potential boron delivery agents for boron neutron capture therapy (BNCT): 2'-O-(o-carboran-1-ylmethyl)uridine (4a), 3'-O-(o-carboran-1-ylmethyl)uridine (4b), s
Autor:
Douglas J. Perkins, Rolf F. Barth, Dianne M. Adams, Abul K. M. Anisuzzaman, Werner Tjarks, Albert H. Soloway, L. Liu
Publikováno v:
Journal of Medicinal Chemistry. 35:1628-1633
The following boron-containing nucleoside and glucose derivatives have been synthesized as potential boron delivery agents for boron neutron capture therapy (BNCT): 2'-O-(o-carboran-1-ylmethyl)uridine (4a), 3'-O-(o-carboran-1-ylmethyl)uridine (4b), s