Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Dianne K, Hammond"'
Autor:
Duane L. Pierson, Satish K. Mehta, Larry H. Rohde, Antony S. Jeevarajan, Kamal Emami, Honglu Wu, Ye Zhang, Rachael C. Casey, Dianne K. Hammond
Publikováno v:
DNA Repair. 7:1835-1845
Changes of gene expression profile are one of the most important biological responses in living cells after ionizing radiation (IR) exposure. Although some studies have shown that genes up-regulated by IR may play important roles in DNA damage repair
Autor:
Dianne K. Hammond, Mohan Shenoy, Janet A. Oka, Antonella Casola, Roberto P. Garofalo, Randall M. Goldblum, Paul H. Weigel, Carlton R. Caflisch, Tetsuro Kitamura, Atsushi Kamijo
Publikováno v:
The Journal of Immunology. 164:5029-5034
Binding and transport of polymeric Igs (pIgA and IgM) across epithelia is mediated by the polymeric Ig receptor (pIgR), which is expressed on the basolateral surface of secretory epithelial cells. Although an Fc receptor for IgA (FcαR) has been iden
Autor:
Carlton R. Caflisch, Dianne K. Hammond, Janet A. Oka, Paul H. Weigel, Steven C. Diven, Randall M. Goldblum
Publikováno v:
Kidney International. 54:837-847
IgA induced activation of human mesangial cells: Independent of Fc α R1 (CD 89). Background IgA nephropathy (IgAN) is characterized by deposition of polymers of IgA 1 in the mesangium, accumulation of mesangial matrix and mesangial cell proliferatio
Publikováno v:
Toxicology and Applied Pharmacology. 145:54-60
Estradiol induces kidney tumors in Syrian hamsters. The elevated conversion of estradiol to 4-hydroxylated metabolites in kidney compared to the predominant 2-hydroxylation in liver and other organs, where tumors are not induced by this treatment, ha
Autor:
Antony S. Jeevarajan, Stephen C. Pelsue, Qin Qin, Sandra S. Wise, Amie L. Holmes, Hong Xie, Kellie Joyce, William T. Wallace, Dianne K. Hammond, Cheng Peng, Jamie L. Young, John Pierce Wise
Publikováno v:
Toxicology and applied pharmacology. 234(3)
Hexavalent chromium Cr(VI) is a respiratory toxicant and carcinogen, with solubility playing an important role in its carcinogenic potential. Zinc chromate, a water insoluble or 'particulate' Cr(VI) compound, has been shown to be carcinogenic in epid
Autor:
Todd F, Elliott, Gokul C, Das, Dianne K, Hammond, Robert J, Schwarzkopf, Leslie B, Jones, Tacey L, Baker, John E, Love
Publikováno v:
Gravitational and space biology bulletin : publication of the American Society for Gravitational and Space Biology. 18(2)
Publikováno v:
Toxicology and applied pharmacology. 150(2)
The threshold for hepatotoxicity and cholestasis induced by methylene dianiline (DAPM) in rats is between 25 and 75 mg/kg (Bailie et al., Environ. Health Perspect., 124, 25-30, 1993). Our objectives were to determine if a minimally toxic dose of DAPM
Publikováno v:
Molecular and Cellular Biochemistry. 102
Cytochrome P450 is known to cause carcinogen activation and correspondingly increased cancer risk in animal models. In order to determine whether P450 in the colon may be involved in cancer development in the human, the human colon cell line LS174T w
Publikováno v:
Methods in Enzymology ISBN: 9780121821074
Publisher Summary This chapter discusses the identification and localization of cytochromes P450 in gut. For any tissue, an array of methods is available for the detection of cytochromes P450 and cytochrome P450-dependent activity. First, activity as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a63451861a4c806b7d0164f7899843c4
https://doi.org/10.1016/0076-6879(91)06135-p
https://doi.org/10.1016/0076-6879(91)06135-p
Autor:
Dianne K. Hammond, Henry W. Strobel
Publikováno v:
Molecular and cellular biochemistry. 93(2)
The effects of culture variables on the specific content and activity of various enzymes of the drug metabolizing system were assessed in colon tumor cell line LS174T. The NADH reduced cytochrome b5 (cyt b5)4 spectrum of these cells was similar to ra