Apolipoprotein C-I binds free fatty acids and reduces their intracellular esterification

Autor: Marit Westerterp, Jimmy F.P. Berbée, Dianne J.M. Delsing, Miek C. Jong, Marion J.J. Gijbels, Vivian E.H. Dahlmans, Erik H. Offerman, Johannes A. Romijn, Louis M. Havekes, Patrick C.N. Rensen

Publikováno v: Journal of Lipid Research, Vol 48, Iss 6, Pp 1353-1361 (2007)

Mice that overexpress human apolipoprotein C-I (apoC-I) homozygously (APOC1+/+ mice) are protected against obesity and show cutaneous abnormalities. Although these effects can result from our previous observation that apoC-I inhibits FFA generation b

Externí odkaz: https://doaj.org/article/cf02ed55ce8448b3afd5f2f12f921c74

Cannabinoid Receptor 2 Deficiency in Haematopoietic cells Aggravates Early Atherosclerosis in LDL Receptor Deficient Mice

Autor: Frank P Leijten, Anja Garritsen, Marion J.J. Gijbels, Karin Arts, Hans van Eenennaam, Dianne J.M. Delsing, Andrea van Elsas, Menno P.J. de Winther

Publikováno v: open cardiovascular medicine journal, 5, 15-21. Bentham Science Publishers B.V.
The Open Cardiovascular Medicine Journal

Objective: The cannabinoid receptor 2 (CB2) has been implicated to play a role in various inflammatory proc- esses. Since atherosclerosis is currently considered a chronic inflammatory disease, we studied the effect of haema- topoietic CB2 deficiency

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85c4395b6b09126697c89fdc67554e6e
https://doi.org/10.2174/1874192401105010015

Effects of amlodipine, atorvastatin and the combination of both on advanced atherosclerotic plaque in APOE*3-Leiden transgenic mice

Autor: Gerwin J. Puppels, J. Wouter Jukema, Sweder W.E van de Poll, Louis M. Havekes, Hans M.G. Princen, Arnoud van der Laarse, Dianne J.M. Delsing

Publikováno v: Journal of Molecular and Cellular Cardiology, 35(1), 109-118. Academic Press

Combined treatment of statins and calcium channel blockers has been suggested to be superior to statin therapy alone. We quantified the anti-atherosclerotic potential of amlodipine, atorvastatin and their combination on existing atherosclerotic plaqu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::306ec2a3a19c88b19e89ce6d947e4932
https://doi.org/10.1016/s0022-2828(02)00284-5

Apolipoprotein C-I binds free fatty acids and reduces their intracellular esterification

Autor: Johannes A. Romijn, V.E.H. Dahlmans, Jimmy F.P. Berbée, Patrick C.N. Rensen, Marit Westerterp, Marion J.J. Gijbels, Dianne J.M. Delsing, Miek C. Jong, E.H. Offerman, Louis M. Havekes

Publikováno v: Journal of Lipid Research, 48(6), 1353-1361. AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
Journal of Lipid Research, Vol 48, Iss 6, Pp 1353-1361 (2007)
Journal of lipid research, 48(6), 1353-1361. American Society for Biochemistry and Molecular Biology Inc.

Mice that overexpress human apolipoprotein C-I (apoC-I) homozygously (APOC1+/+ mice) are protected against obesity and show cutaneous abnormalities. Although these effects can result from our previous observation that apoC-I inhibits FFA generation b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::424f2a2e13258c112cf23ab3c4be72f4
https://research.rug.nl/en/publications/e7f445ce-c102-400b-8dc6-a8c65fd4f01a

VLDL receptor deficiency enhances intimal thickening after vascular injury but does not affect atherosclerotic lesion area

Autor: P.J. Tacken, Ko Willems van Dijk, Marion J.J. Gijbels, Marten H. Hofker, Dianne J.M. Delsing, Louis M. Havekes, Paul H.A. Quax

Publikováno v: Atherosclerosis, 162(1), 103-110. Elsevier Ireland Ltd

Department of Human and Clinical Genetics, Leiden University Medical Center, PO Box 9503, 2300 RA Leiden, The Netherlands.The very low density lipoprotein receptor (VLDLR) has been shown to modulate cell migration and foam cell formation in vitro. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04c2eadfa236ef56884e4868b3809c32
https://pubmed.ncbi.nlm.nih.gov/11947903