Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Dianne J. Beveridge"'
Autor:
Dianne J. Beveridge, Kirsty L. Richardson, Michael R. Epis, Rikki A. M. Brown, Lisa M. Stuart, Andrew J. Woo, Peter J. Leedman
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract RNA-based therapeutics are emerging as innovative options for cancer treatment, with microRNAs being attractive targets for therapy development. We previously implicated microRNA-642a-5p (miR-642a-5p) as a tumor suppressor in prostate cancer
Externí odkaz:
https://doaj.org/article/cb9118786c3647f78f95a546270cae69
Autor:
Andrew J. Woo, Peter J. Leedman, Michael R. Epis, Lisa M. Stuart, Kirsty L. Richardson, Dianne J. Beveridge, Rikki A. M. Brown
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports
RNA-based therapeutics are emerging as innovative options for cancer treatment, with microRNAs being attractive targets for therapy development. We previously implicated microRNA-642a-5p (miR-642a-5p) as a tumor suppressor in prostate cancer (PCa), a
Autor:
Peter J. Leedman, Andrew J. Woo, Kirsty L. Richardson, Dianne J. Beveridge, Tasnuva D. Kabir, Lisa M. Stuart
Publikováno v:
Cancer Research. 81:2379-2379
Hepatocellular carcinoma (HCC) is increasing in incidence, has a very poor prognosis and presents massive global unmet clinical need. Current treatment of advanced HCC with sorafenib and other targeted therapies offers short-term relief with little s
Autor:
Kirsty L. Richardson, Jacqueline M. Bentel, Keith M. Giles, Michael R. Epis, Peter J. Leedman, Lisa M. Stuart, Patrick A. Candy, Ronald J. Cohen, Dianne J. Beveridge
Publikováno v:
Oncotarget
// Michael R. Epis 1, * , Keith M. Giles 1, 4, * , Dianne J. Beveridge 1, * , Kirsty L. Richardson 1 , Patrick A. Candy 1 , Lisa M. Stuart 1 , Jacqueline Bentel 2 , Ronald J. Cohen 5 and Peter J. Leedman 1, 3 1 Laboratory for Cancer Medicine, Harry P
Autor:
Larissa C. Wintle, Lisa M. Stuart, Kirsty L. Richardson, Tasnuva D. Kabir, Rikki A. M. Brown, Michael R. Epis, Peter J. Leedman, Marisa H. De Pinho, Felicity C. Kalinowski, Jessica L. Horsham, Dianne J. Beveridge
Publikováno v:
MicroRNA and Cancer ISBN: 9781493974337
MicroRNAs (miRNAs) are a family of short noncoding RNA molecules that fine-tune expression of mRNAs. Often their altered expression is associated with a number of diseases, including cancer. Given that miRNAs target multiple genes and "difficult to d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22a198651cd141a5966a0449f469945c
https://doi.org/10.1007/978-1-4939-7435-1_12
https://doi.org/10.1007/978-1-4939-7435-1_12
Autor:
Jacob George, Larissa C. Wintle, Michael R. Epis, Felicity C. Kalinowski, Vishal Chaturvedi, Rikki A. M. Brown, Kirsty L. Richardson, Patrick A. Candy, Peter J. Leedman, Dianne J. Beveridge, Clarissa Ganda, Christina Kopp, Tasnuva D. Kabir, George C.T. Yeoh, Lisa M. Stuart
Publikováno v:
Hepatology (Baltimore, Md.). 67(1)
Sorafenib remains the only approved drug for treating patients with advanced hepatocellular carcinoma (HCC). However, the therapeutic effect of sorafenib is transient, and patients invariably develop sorafenib resistance (SR). Recently, TYRO3, a memb
Publikováno v:
Experimental and Clinical Endocrinology & Diabetes. 103:58-62
Both hepatic and renal regeneration are associated with rapid increases in hepatocyte growth factor (HGF)mRNA levels, not only in the regenerating tissue, but also in the lung. In this study, changes in the levels of HGF mRNA in the terminal ileum an
Autor:
Peter J. Leedman, Melissa A. Brown, Stacey L. Edwards, Jodi M. Saunus, Andrew D. Davidson, Glenn Francis, Dianne J. Beveridge, Juliet D. French, Sarah A. Wagner, Esme C. Hatchell, Sandra Stein, Kaylene J. Simpson
Publikováno v:
Cancer Research. 68:9469-9478
BRCA1 is a breast cancer susceptibility gene that is down-regulated in a significant proportion of sporadic breast cancers. BRCA1 is posttranscriptionally regulated by RNA-binding proteins, the identities of which are unknown. HuR is an RNA binding p
Autor:
Henry Furneaux, Keith M. Giles, Andrew M. Thomson, Dominic C. Voon, John M. Daly, Dianne J. Beveridge, Peter J. Leedman, Jalal A. Jazayeri
Publikováno v:
Journal of Biological Chemistry. 278:2937-2946
Despite promoting growth in many cell types, epidermal growth factor (EGF) induces growth inhibition in a variety of cancer cells that overexpress its receptor. The cyclin-dependent kinase inhibitor p21(WAF1) is a central component of this pathway. W
Autor:
Jalal A. Jazayeri, Caroline E Walker, Andrew M. Thomson, Dianne J. Beveridge, Peter J. Leedman, Lois Balmer
Publikováno v:
Molecular and Cellular Biology. 21:2070-2084
The epidermal growth factor (EGF) receptor (EGF-R) is a protein tyrosine kinase receptor that is the target for high-affinity ligands, such as EGF and transforming growth factor alpha. EGF-R shares extensive homology with the erbB oncogene product of