Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Dianne C Mitchell"'
Autor:
Jessica M Stiles, Clarissa Amaya, Steven Rains, Dolores Diaz, Robert Pham, James Battiste, Jaime F Modiano, Victor Kokta, Laura E Boucheron, Dianne C Mitchell, Brad A Bryan
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e60021 (2013)
Therapeutic targeting of the beta-adrenergic receptors has recently shown remarkable efficacy in the treatment of benign vascular tumors such as infantile hemangiomas. As infantile hemangiomas are reported to express high levels of beta adrenergic re
Externí odkaz:
https://doaj.org/article/4b2b549a97aa468090e7e8cace6fc211
Autor:
Guillaume Gapihan, Anne Janin, Ivan Bièche, Celia Dos Santos, Brad A. Bryan, Dianne C. Mitchell, Maria E. Riveiro, Annemilaï Tijeras-Raballand, Maria Serova, Sandrine Faivre, Guilhem Bousquet, Alfred Lopez, Matthieu Martinet, Armand de Gramont, Cindy Neuzillet, Eric Raymond
Publikováno v:
Oncotarget
// Maria Serova 1, 2, 3 , Annemilai Tijeras-Raballand 1, 2, 3 , Celia Dos Santos 1, 2, 3 , Matthieu Martinet 1 , Cindy Neuzillet 2, 3 , Alfred Lopez 4 , Dianne C. Mitchell 4 , Brad A. Bryan 4 , Guillaume Gapihan 3, 5 , Anne Janin 3, 5 , Guilhem Bousq
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-13 (2017)
BMC Cancer
BMC Cancer
Background The serine/threonine protein kinases ROCK1 and 2 are key RhoA-mediated regulators of cell shape and cytoskeletal dynamics. These proteins perform multiple functions in vascular endothelial cell physiology and are attractive targets for can
Autor:
Rajkumar Lakshmanaswamy, A Perkins, Alexander Hackathorn, Brad A. Bryan, C Doty, K Masterjohn, James K. Liao, Carrie Spencer, Arunkumar Arumugam, Pat P. Ongusaha, J Montalvo, Dianne C. Mitchell
Publikováno v:
Current Molecular Medicine
The serine/threonine protein kinase paralogs ROCK1 & 2 have been implicated as essential modulators of angiogenesis; however their paralog-specific roles in endothelial function are unknown. shRNA knockdown of ROCK1 or 2 in endothelial cells resulted
Autor:
Mary Lacaze, Laura E. Boucheron, Robert Pham, Brad A. Bryan, Victor Kokta, Clarissa N. Amaya, Rebecca K. Rowntree, Arlynn F. Mulne, Dianne C. Mitchell, Jessica M. Stiles, Joyce Bischoff
Publikováno v:
Experimental and Therapeutic Medicine
Infantile hemangiomas (IHs) are non-malignant, largely cutaneous vascular tumors affecting approximately 5-10% of children to varying degrees. During the first year of life, these tumors are strongly proliferative, reaching an average size ranging fr
Autor:
Ravindra Kumar, Roselyne Castonguay, Travis E. Monnell, Jasbir Seehra, Kathryn W. Underwood, Dianne C. Mitchell, Aaron W. Mulivor, Eileen Pobre, R. Scott Pearsall, Nicolas Solban, Jeffrey A. Ucran, Asya Grinberg
Publikováno v:
Molecular Cancer Therapeutics. 9:379-388
Activin receptor–like kinase-1 (ALK1) is a type I, endothelial cell–specific member of the transforming growth factor-β superfamily of receptors known to play an essential role in modulating angiogenesis and vessel maintenance. In the present st
Autor:
Brad A. Bryan, Angel E. Maldonado, Patricia A. D'Amore, Josh S. Havumaki, Tony E. Walshe, Magali Saint-Geniez, Arindel S.R. Maharaj, Dianne C. Mitchell
Publikováno v:
Molecular Biology of the Cell. 19:994-1006
Angiogenesis is largely controlled by hypoxia-driven transcriptional up-regulation and secretion of vascular endothelial growth factor (VEGF) and its binding to the endothelial cell tyrosine receptor kinases, VEGFR1 and VEGFR2. Recent expression anal
Autor:
Mingyao Liu, Stephen Safe, Lewis J. Stafford, Dianne C. Mitchell, Jinsheng Weng, Maen Abdelrahim, Menashe Bar-Eli
Publikováno v:
Journal of Biological Chemistry. 281:51-58
KiSS-1 has been shown to function as a tumor metastasis suppressor gene and reduce the number of metastases in different cancers. The expression of KiSS-1 or KiSS1, like other tumor suppressor, is commonly reduced or completely ablated in a variety o
Autor:
Lewis J. Stafford, Jinsheng Weng, Yi Cai, Jianghua Wang, Dianne C. Mitchell, Mingyao Liu, Michael Ittmann
Publikováno v:
International Journal of Cancer. 113:811-818
The G-protein-coupled receptors and signal transduction pathways represent important specific targets for a variety of human diseases, ranging from the control of blood pressure, allergic response, hormonal disorders and neurologic diseases to tumori
Autor:
Richard Guyon, Frode Lingaas, Amy L. Lonkar, Francis Galibert, Jennifer K. Lowe, Keith E. Murphy, Dianne C. Mitchell, Melissa L. Cox, Elaine A. Ostrander, Catherine André
Publikováno v:
Functional & Integrative Genomics. 3:112-116
We are interested in the collagen gene superfamily and its involvement in hereditary diseases of the human and domestic dog. Presented here is radiation hybrid mapping of the type I and type IV collagen gene subfamilies on the most recent version of